The impact of COVID vaccination on incidence of long COVID and healthcare resource utilisation in a primary care cohort in England, 2021-2022 DOI Creative Commons
Jingyan Yang, Kiran Rai,

Tamuno Alfred

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: April 25, 2024

ABSTRACT Background Long COVID, a diverse set of symptoms that persist after minimum 4 weeks from the initial SARS-CoV-2 infection, has posed substantial burden to healthcare systems. There is some evidence COVID-19 vaccination may be associated with lower risk long COVID. However, little known about association between status and COVID-associated resource utilisation (HCRU) costs. Methods We conducted cohort study using primary care electronic health record data in England Clinical Practice Research Datalink (CPRD) Aurum dataset linked Hospital Episode Statistics where applicable. Adult (≥18 years) patients were indexed on diagnosis 1 st March 2021 December 2021. Vaccination was assessed at index: unvaccinated or completed series (two doses for immunocompetent three immunocompromised patients). Covariate balance entropy balancing. Weighted multivariable Poisson regression used estimate incidence rate ratio (IRR) incident separately COVID use, by status. Patients followed up maximum 9-months post index. Results A total 35,713 who had vaccination, 75,522 included. The weighted adjusted IRR among vaccinated compared being 0.81 (95% CI: 0.77-0.86) overall cohort, 0.83 0.78-0.88) 0.28 0.13-0.58) cohort. Among those there no consultations cohorts. Cost greater group than series. Conclusion against reduce both patients. found frequency visits diagnosed Future studies larger sample size, higher vaccine uptake, longer periods during pandemic are needed further quantify impact

Language: Английский

E-cigarettes are not associated with post-acute COVID-19 syndrome among US adults DOI Creative Commons
Shahryar Rajai Firouzabadi, Ida Mohammadi,

Mohammadreza Alinejadfard

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 22, 2025

Language: Английский

Citations

0
The impact of COVID vaccination on incidence of long COVID and healthcare resource utilisation in a primary care cohort in England, 2021–2022 DOI Creative Commons
Jingyan Yang, Kiran Rai,

Tamuno Alfred

et al.

BMC Infectious Diseases, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 13, 2025

Long COVID, a diverse set of symptoms that persist after minimum 4 weeks from the initial SARS-CoV-2 infection, has posed substantial burden to healthcare systems. There is some evidence COVID-19 vaccination may be associated with lower risk long COVID. However, little known about association between status and COVID-associated resource utilisation (HCRU) costs. We conducted cohort study using primary care electronic health record data in England Clinical Practice Research Datalink (CPRD) Aurum dataset linked Hospital Episode Statistics where available. Adult (≥ 18 years) patients were indexed on diagnosis 1st March 2021 December 2021. Vaccination was assessed at index: unvaccinated or completed series (two doses for immunocompetent three immunocompromised patients). Covariate balance entropy balancing. Weighted multivariable Poisson regression used estimate incidence rate ratio (IRR) incident separately COVID use, by status. Patients followed up maximum 9-months post index. A total 35,713 who had vaccination, 75,522 included. The weighted adjusted IRR among vaccinated compared being 0.81 (95% CI: 0.77–0.86) overall cohort, 0.83 0.78–0.88) 0.28 0.13–0.58) cohort. Among those there no consultations cohorts. Cost greater group than series. against reduce both patients. found frequency visits diagnosed Future studies larger sample size, higher vaccine uptake, longer periods during pandemic are needed further quantify impact

Language: Английский

Citations

0
Long COVID Syndrome: A Narrative Review on Burden of Age and Vaccination DOI Open Access
Panaiotis Finamore, Elena Arena,

Domenica Marika Lupoi

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(16), P. 4756 - 4756

Published: Aug. 13, 2024

Background/Objective: The COVID-19 pandemic has led to the emergence of post-acute syndrome, also known as long COVID, which presents a significant challenge due its varied symptoms and unpredictable course, particularly in older adults. Similar infections, factors such age, pre-existing health conditions, vaccination status may influence occurrence severity COVID. objective is analyze role aging context COVID investigate prevalence rates efficacy improve prevention strategies treatment this age group. Methods: Four researchers independently conducted literature search PubMed database trace studies published between July 2020 2024. Results: Aging influences both likelihood developing recovery process, age-related physiological changes, immune system alterations, presence comorbidities. Vaccination plays key reducing risk by attenuating inflammatory responses associated with symptoms. Conclusions: Despite protection vaccines offer against severe infection, hospitalization, post-infection sequelae, vaccine hesitancy remains major obstacle, worsening impact Promising treatments for condition include antivirals although further research needed.

Language: Английский

Citations

2
Occupational COVID-19: can we claim that compensation is causation? DOI Open Access
Sara De Matteis

Occupational and Environmental Medicine, Journal Year: 2024, Volume and Issue: 81(4), P. 169 - 170

Published: April 1, 2024

Language: Английский

Citations

1
Prevalence and symptoms of Long Covid-19 in the workplace DOI Creative Commons
Hanizah Mohd Yusoff, Sheng Qian Yew, Azmawati Mohammed Nawi

et al.

Occupational Medicine, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Abstract Background The symptoms of Long coronavirus disease 2019 (Covid-19) are heterogeneous, creating uncertainty for employers regarding the diagnosis. prevalence Covid-19 in workforce is also unknown. Furthermore, workers affected by encounter considerable difficulties ensuring work safety and returning to their jobs due this condition. Aims This review aimed identify workplace determine various experienced workers. Methods A meta-analysis was conducted calculate pooled estimates Covid-19. Heterogeneity among evaluated using I² statistic. Results across 11 studies 38% (95% CI 23–56). total 43 associated with were identified workplace, top five being dyspnoea at moderate activity (51%, 95% 39–62), mental (38%, 6–87), mild (35%, 25–47), fatigue (26%, 3–78) effort intolerance (24%, 15–35). Conclusions indicates a significant burden long-lasting within workforce. reported during activities, symptoms, intolerance.

Language: Английский

Citations

0
The impact of COVID vaccination on incidence of long COVID and healthcare resource utilisation in a primary care cohort in England, 2021-2022 DOI Creative Commons
Jingyan Yang, Kiran Rai,

Tamuno Alfred

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: April 25, 2024

ABSTRACT Background Long COVID, a diverse set of symptoms that persist after minimum 4 weeks from the initial SARS-CoV-2 infection, has posed substantial burden to healthcare systems. There is some evidence COVID-19 vaccination may be associated with lower risk long COVID. However, little known about association between status and COVID-associated resource utilisation (HCRU) costs. Methods We conducted cohort study using primary care electronic health record data in England Clinical Practice Research Datalink (CPRD) Aurum dataset linked Hospital Episode Statistics where applicable. Adult (≥18 years) patients were indexed on diagnosis 1 st March 2021 December 2021. Vaccination was assessed at index: unvaccinated or completed series (two doses for immunocompetent three immunocompromised patients). Covariate balance entropy balancing. Weighted multivariable Poisson regression used estimate incidence rate ratio (IRR) incident separately COVID use, by status. Patients followed up maximum 9-months post index. Results A total 35,713 who had vaccination, 75,522 included. The weighted adjusted IRR among vaccinated compared being 0.81 (95% CI: 0.77-0.86) overall cohort, 0.83 0.78-0.88) 0.28 0.13-0.58) cohort. Among those there no consultations cohorts. Cost greater group than series. Conclusion against reduce both patients. found frequency visits diagnosed Future studies larger sample size, higher vaccine uptake, longer periods during pandemic are needed further quantify impact

Language: Английский

Citations

0