Left Atrial Appendage Occlusion in Patients Without Atrial Fibrillation Undergoing Cardiac Surgery: The Evidence Is Mounting DOI
Mark T Mills, Bilal H. Kirmani, Gregory Y.H. Lip

et al.

Circulation Cardiovascular Interventions, Journal Year: 2024, Volume and Issue: 17(10)

Published: Sept. 11, 2024

Language: Английский

2024 Chinese Expert Consensus Guidelines on the Diagnosis and Treatment of Atrial Fibrillation in the Elderly, Endorsed by Geriatric Society of Chinese Medical Association (Cardiovascular Group) and Chinese Society of Geriatric Health Medicine (Cardiovascular branch): Executive Summary DOI Creative Commons

Yutang Wang,

Yutao Guo,

M. Qin

et al.

Thrombosis and Haemostasis, Journal Year: 2024, Volume and Issue: 124(10), P. 897 - 911

Published: May 14, 2024

The consensus guidelines of the Geriatric Society Chinese Medical Association on management atrial fibrillation (AF) in elderly was first published 2011 and updated 2016, with endorsement by Health Medicine. Since then, many important studies regarding screening treatment population have been reported, necessitating this expert guideline. writing committee members comprehensively reviewed evidence pertaining to patients AF, formulated 2024 update. highlighted issues focused following: for geriatric comprehensive assessment, use Atrial Better Care (ABC) pathway patients, special clinical settings related AF. New recommendations addressing smart technology facilitated AF screening, ABC based management, optimal anticoagulation were developed, a focus elderly.

Language: Английский

Citations

40

Comorbidity patterns and mortality in atrial fibrillation: a latent class analysis of the EURopean study of Older Subjects with Atrial Fibrillation (EUROSAF) DOI Creative Commons
Huah Shin Ng, Richard Woodman, Nicola Veronese

et al.

Annals of Medicine, Journal Year: 2025, Volume and Issue: 57(1)

Published: Jan. 18, 2025

Background Most older patients with atrial fibrillation (AF) have comorbidities. However, it is unclear whether specific comorbidity patterns are associated adverse outcomes. We identified and their association mortality in multimorbid AF different multidimensional frailty.

Language: Английский

Citations

1

The Role of Early Risk Factor Modification and Ablation in Atrial Fibrillation Substrate Remodeling Prevention DOI Creative Commons
Ioanna Koniari,

Maria Bozika,

Kassiani-Maria Nastouli

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(2), P. 405 - 405

Published: Feb. 7, 2025

Atrial fibrillation (AF) is the most common sustained arrhythmia, contributing to significant morbidity and healthcare burden worldwide. This review evaluates role of early risk factor modification timely catheter ablation in preventing AF progression improving patient outcomes. A comprehensive literature search was conducted using PubMed, MEDLINE, Google Scholar, focusing on studies published after ESC 2020 guidelines for diagnosis management up release updated 2024 AF. Keywords included "atrial fibrillation", "catheter ablation", "risk management", "psychological stress". Relevant clinical trials, randomized controlled systematic reviews, meta-analyses were included, with particular emphasis novel recommendations. Traditional factors such as obesity, hypertension, diabetes, sleep apnea, alcohol consumption, physical exertion are well established progression. Early evidence also suggests a psychological stress mood disorders, including depression post-traumatic disorder (PTSD), increasing susceptibility. Psychological disorders linked primarily through behavioral changes poor medication adherence, unhealthy lifestyle choices, increased substance use. Recent recommend selected patients reduce burden, prevent atrial remodeling, improve quality life, particularly those resistant antiarrhythmic drugs or individuals AF-induced cardiomyopathy. Furthermore, we highlight importance patient-centered, multidisciplinary approach, integrating electrophysiologists, cardiologists, primary care providers structured interventions shared decision-making. Despite these advances, gaps remain defining optimal timing, selection, long-term benefits persistent AF, necessitating need further research. By intervention, personalized treatment strategies, collaborative models, may usher paradigm shift management, cardiovascular outcomes life.

Language: Английский

Citations

1

Prognostic implications of iron deficiency in patients with atrial fibrillation, with and without chronic heart failure DOI
Abdullahi Ahmed Mohamed, Daniel Christensen, Milan Mohammad

et al.

Heart, Journal Year: 2025, Volume and Issue: unknown, P. heartjnl - 325244

Published: Feb. 8, 2025

Background Iron deficiency (ID) is common in patients with atrial fibrillation/flutter (AF), but its prognostic implications and optimal diagnostic criteria, particularly those without heart failure (HF), remain unclear. This study assessed the associations between different ID definitions clinical outcomes AF. Methods Danish nationwide cohort included 10 834 AF who underwent iron studies 2008 2019, stratified by HF status. was defined using four criteria: European Society of Cardiology (ESC) guidelines, ferritin <100 ng/mL, transferrin saturation (TSAT) <20% serum ≤13 µmol/L. Associations all-cause mortality, cardiovascular mortality hospitalisation were evaluated Cox regression models, adjusted for confounders. Results Prevalence varied substantially across definitions, ranging from 36.2% to 62.7%. Over a median follow-up 31 months, TSAT associated increased both (HR 1.25, 95% CI 1.14 1.37 HR 1.31, 1.49, respectively) 1.39, 1.18 1.64 1.54, 2.00, respectively). Similarly, µmol/L higher 1.44, 1.31 1.58 1.42, 1.24 1.63, 1.67, 1.41 1.97 1.46, 1.13 1.89, ESC guidelines or ng/mL not either group linked 1.15, 1.08 1.23 1.16, 1.09 1.23, Conclusions AF, irrespective status, highlighting these criteria as clinically relevant risk stratification.

Language: Английский

Citations

1

The Elderly Patient with Atrial Fibrillation: Optimal Treatment Strategies DOI Open Access
Fabiana Lucà, Iris Parrini

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(5), P. 1753 - 1753

Published: March 5, 2025

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, with its prevalence expected to rise significantly due global population aging [...]

Language: Английский

Citations

1

Fibrinaloid Microclots and Atrial Fibrillation DOI Creative Commons
Douglas B. Kell, Gregory Y.H. Lip, Etheresia Pretorius

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(4), P. 891 - 891

Published: April 17, 2024

Atrial fibrillation (AF) is a comorbidity of variety other chronic, inflammatory diseases for which fibrinaloid microclots are known accompaniment (and in some cases, cause, with mechanistic basis). Clots are, course, well-known consequence atrial fibrillation. We here ask the question whether seen plasma or serum may fact also be cause (or contributor to) development AF. consider ‘risk factors’ AF, and particular, exogenous stimuli such as infection air pollution by particulates, both to The external accompaniments bacterial (lipopolysaccharide lipoteichoic acids) viral (SARS-CoV-2 spike protein) infections stimulate when added vitro, microclots, amyloid proteins, can cytotoxic, inducing hypoxia/reperfusion means. Strokes thromboembolisms common consequences Consequently, taking systems approach, we review considerable evidence detail, leads us suggest that it likely well have an aetiological role This has significant therapeutic implications.

Language: Английский

Citations

5

Integrating AI-driven wearable devices and biometric data into stroke risk assessment: A review of opportunities and challenges DOI Creative Commons
David B. Olawade, Nicholas Aderinto, Aanuoluwapo Clement David-Olawade

et al.

Clinical Neurology and Neurosurgery, Journal Year: 2024, Volume and Issue: 249, P. 108689 - 108689

Published: Dec. 10, 2024

Stroke is a leading cause of morbidity and mortality worldwide, early detection risk factors critical for prevention improved outcomes. Traditional stroke assessments, relying on sporadic clinical visits, fail to capture dynamic changes in such as hypertension atrial fibrillation (AF). Wearable technology (devices), combined with biometric data analysis, offers transformative approach by enabling continuous monitoring physiological parameters. This narrative review was conducted using systematic identify analyze peer-reviewed articles, reports, case studies from reputable scientific databases. The search strategy focused articles published between 2010 till date pre-determined keywords. Relevant were selected based their focus wearable devices AI-driven technologies prevention, diagnosis, rehabilitation. literature categorized thematically explore applications, opportunities, challenges, future directions. explores the current landscape assessment, focusing role detection, personalized care, integration into practice. highlights opportunities presented predictive analytics, where algorithms can provide tailored interventions. Personalized powered machine learning, enable individualized care plans. Furthermore, telemedicine facilitates remote patient rehabilitation, particularly underserved areas. Despite these advances, challenges remain. Issues accuracy, privacy concerns, wearables healthcare systems must be addressed fully realize potential. As evolves, its application could revolutionize improving outcomes reducing global burden stroke.

Language: Английский

Citations

5

Multidisciplinary Approach in Atrial Fibrillation: As Good as Gold DOI Open Access
Fabiana Lucà, Maurizio Giuseppe Abrignani,

Fabrizio Oliva

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(16), P. 4621 - 4621

Published: Aug. 7, 2024

Atrial fibrillation (AF) represents the most common sustained arrhythmia necessitating dual focus: acute complication management and longitudinal oversight to modulate disease progression ensure comprehensive patient care over time. AF is a multifaceted disorder; due such great number of potential exacerbating conditions, multidisciplinary team (MDT) should manage patients by cooperating with cardiologist. Effective necessitates implementation well-coordinated tailored pathway aimed at delivering optimized treatment through collaboration among various healthcare professionals. Management be carefully evaluated mutually agreed upon in consultation providers. It crucial recognize that may evolve emergence new risk factors, symptoms, progression, advancements modalities. In context teams, coordinated approach involves assembling diverse meet individual patients’ unique needs based on local services’ availability.

Language: Английский

Citations

4

Sex Differences in Atrial Remodeling and Atrial Fibrillation Recurrence After Catheter Ablation DOI
Fabiana Duarte, R. Silva-Teixeira, Inês Aguiar‐Neves

et al.

Heart Rhythm, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0

Diagnosis and management of comorbid disease in COPD DOI Open Access

Eleanor Cronin,

Breda Cushen

Breathe, Journal Year: 2025, Volume and Issue: 21(1), P. 240099 - 240099

Published: Jan. 1, 2025

COPD is one of the most common chronic respiratory conditions and associated with high healthcare use, morbidity mortality. Multimorbidity in confers a worse prognosis. Despite this, there delayed often under-diagnosis comorbid diseases COPD. Knowledge non-respiratory pathologies that can coexist essential to ensure early detection appropriate management. This review provides an overview comorbidities have been described We discuss their pathogenesis, pitfalls diagnosis, strategies for prevention treatment.

Language: Английский

Citations

0