Jurnal Jamu Indonesia,
Journal Year:
2022,
Volume and Issue:
7(3), P. 102 - 110
Published: Dec. 30, 2022
This
research
aimed
to
determine
the
active
fraction
and
profile
of
compounds
in
Manonjaya
sSnakefruit
skin
extract
that
can
be
used
as
antidiabetic
activity
using
zebra
fish.
was
extracted
by
maceration
70%
ethanol
then
fractionated
n-hexane,
ethyl
acetate
methanol.
The
showed
highest
yield
total
phenolic
content
well
strongest
α-glucosidase
inhibition
with
an
percentage
64.43%.
provided
most
spot
inhibitor.
act
compound
is
flavonoid
from
glycosylflavone
flavone
groups.
Antidiabetic
fish
indicates
Snakefruit
decrease
blood
sugar
level
after
induced
alloxan.
crude
group
had
54.51%
lower
than
induction
41.70%
negative
control.
Meanwhile,
65.10%
55.27%
Depression and Anxiety,
Journal Year:
2024,
Volume and Issue:
2024(1)
Published: Jan. 1, 2024
The
escalating
global
prevalence
of
type
2
diabetes
mellitus
(T2DM)
and
mental
disorder
(MD)
including
schizophrenia,
bipolar
disorder,
major
depressive
anxiety
highlights
the
urgency
for
comprehensive
therapeutic
strategies.
Aerobic
exercise
(AE)
is
a
viable
adjunct
therapy,
providing
significant
benefits
individuals
dealing
with
both
T2DM
MD.
This
review
consolidates
evidence
on
AE's
role
in
alleviating
physiological
psychological
effects
these
comorbid
conditions.
It
delves
into
pathophysiological
connections
between
various
MD,
depression,
anxiety,
disorder-emphasizing
their
reciprocal
exacerbation.
Key
neurophysiological
mechanisms
through
which
AE
confers
are
explored,
neuroinflammation
modulation,
brain
structure
neuroplasticity
enhancement,
growth
factor
expression
regulation,
hypothalamic-pituitary-adrenal
(HPA)/microbiota-gut-brain
(MGB)
axis
normalization.
Clinical
results
indicate
that
significantly
improves
metabolic
parameters
patients
substantial
argument
integrating
treatment
plans.
Future
research
should
aim
to
establish
detailed,
personalized
prescriptions
explore
long-term
this
population.
underscores
potential
complement
existing
modalities
enhance
management
Neurogastroenterology & Motility,
Journal Year:
2023,
Volume and Issue:
35(12)
Published: Sept. 24, 2023
Zebrafish
larvae
are
translucent,
allowing
in
vivo
analysis
of
gut
development
and
physiology,
including
motility.
While
recent
progress
has
been
made
measuring
motility
larvae,
challenges
remain
which
can
influence
results,
such
as
how
data
interpreted,
opportunities
for
technical
user
error,
inconsistencies
methods.
Jurnal Jamu Indonesia,
Journal Year:
2022,
Volume and Issue:
7(3), P. 102 - 110
Published: Dec. 30, 2022
This
research
aimed
to
determine
the
active
fraction
and
profile
of
compounds
in
Manonjaya
sSnakefruit
skin
extract
that
can
be
used
as
antidiabetic
activity
using
zebra
fish.
was
extracted
by
maceration
70%
ethanol
then
fractionated
n-hexane,
ethyl
acetate
methanol.
The
showed
highest
yield
total
phenolic
content
well
strongest
α-glucosidase
inhibition
with
an
percentage
64.43%.
provided
most
spot
inhibitor.
act
compound
is
flavonoid
from
glycosylflavone
flavone
groups.
Antidiabetic
fish
indicates
Snakefruit
decrease
blood
sugar
level
after
induced
alloxan.
crude
group
had
54.51%
lower
than
induction
41.70%
negative
control.
Meanwhile,
65.10%
55.27%
