Ultrasonic-assisted membrane processes for the systematic purification of glycyrrhiza wastewater
Cunyu Li,
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Yun Ma,
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Shuwan Tang
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et al.
Ultrasonics Sonochemistry,
Journal Year:
2024,
Volume and Issue:
111, P. 107098 - 107098
Published: Oct. 8, 2024
Language: Английский
Regulation of apoptosis and interaction with cartilage degeneration in osteoarthritis
Frontiers in Cell and Developmental Biology,
Journal Year:
2025,
Volume and Issue:
13
Published: March 27, 2025
Osteoarthritis
(OA)
is
a
chronic
degenerative
joint
disease,
primarily
characterized
by
the
degradation
of
ECM
and
cartilage
degeneration.
Articular
maintained
chondrocytes,
which
secrete
ECM,
making
stability
these
cells
crucial
for
function.
Research
has
shown
that
in
later
stages
OA,
cavities
form,
indicating
decline
chondrocyte
Chondrocyte
death
considered
central
feature
Apoptosis,
form
programmed
cell
death,
plays
key
role
this
process.
While
controlled
apoptosis
helps
remove
damaged
chondrocytes
protects
from
injury,
excessive
disrupts
balance
microenvironment
accelerates
OA
progression.
Therefore,
regulating
may
offer
novel
approach
preventing
treating
This
review
examines
pathways,
interaction
between
regulatory
factors
apoptosis,
analyzes
current
drug
interventions
targeting
both
preclinical
clinical
studies.
It
also
discusses
challenges
outlines
future
research
directions
to
guide
upcoming
Language: Английский
Therapeutic Effect of Liquiritin Carbomer Gel on Topical Glucocorticoid-Induced Skin Inflammation in Mice
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(8), P. 1001 - 1001
Published: July 28, 2024
Glucocorticoids
are
often
used
and
highly
effective
anti-inflammatory
medications,
but
prolonged
topical
application
may
alter
the
epidermis’
normal
structure
function,
potentially
resulting
in
a
number
of
adverse
effects.
Topical
glucocorticoid-induced
skin
inflammation
is
dangerous
condition
that
develops
after
glucocorticoid
use.
The
patients
become
dependent
on
medication
and,
even
stopped,
dermatitis
symptoms
recur,
severely
impairing
their
quality
life.
Thus,
need
to
aggressively
confront
critical.
Prior
research
has
demonstrated
administration
licorice’s
flavonoid
component
liquiritin
stimulates
epidermal
proliferation,
which
turn
enhances
creation
collagen
healing
wounds.
Therefore,
purpose
this
work
was
determine
if
use
carbomer
gel
can
treat
changes
mice
mechanisms
involved.
findings
that,
model
inflammation,
aided
restoration
barrier
function.
These
outcomes
have
been
caused
by
enhanced
expression
proteins
Aquaporin
3,
Keratin
10,
Claudin-1,
as
well
hyaluronan
content.
In
meantime,
dramatically
decreased
TNF-α,
IL-1β,
IL-6,
IFN-γ,
IgE
mice,
according
ELISA
tests.
Furthermore,
treatment
boosted
superoxide
dismutase,
catalase,
malondialdehyde
expression,
counteracting
detrimental
effects
glucocorticoids
epidermis.
summary,
these
imply
damage
through
various
action.
Language: Английский