Influence of lifestyle and the circadian clock on reproduction

Reproductive Medicine and Biology, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 1, 2025

Abstract Background The biological reproductive process requires the precise coordination of annual and daily signals to adapt environmental shifts. Humans animals have developed shared neuroendocrine systems that adapted seasonal light within hypothalamic–pituitary —gonadal axis. However, stability circadian processes is at risk due industrialization contemporary round‐the‐clock lifestyles. These threats include skipping breakfast, excessive artificial illumination during inappropriate hours because irregular work schedules, nighttime urban lighting, widespread pollution from endocrine‐disrupting chemicals. This review aimed explore interplay between lifestyle factors, rhythms, functions. Methods examined reciprocal influences clocks on hormones, exploring underlying mechanisms their implications for fertility health. We emphasized key findings regarding molecular clock components, endocrine pathways, critical importance synchronizing rhythms with hormonal cycles. Main Findings intersection endocrinology biology reveals complex interactions regulation rhythms. Circadian rhythm misalignments including late‐night negatively impact Conclusions More strategies are needed mitigate effects disruption

Language: Английский

Swimming exercise alleviates pathological bone features in curdlan-injected SKG mice by inducing irisin expression

Life Sciences, Journal Year: 2024, Volume and Issue: 352, P. 122894 - 122894

Published: July 4, 2024

Language: Английский

The role of interleukin-10 in mitigating endoplasmic reticulum stress in aged mice through exercise

AJP Endocrinology and Metabolism, Journal Year: 2024, Volume and Issue: 327(3), P. E384 - E395

Published: July 31, 2024

Aging elevates endoplasmic reticulum (ER) stress in skeletal muscle, potentially heightening inflammation by opposing interleukin-10 (IL-10) effects. This study found that short-term combined exercise boosted strength and IL-10 protein levels while reducing CHOP older mice. In addition, IL-10-deficient mice exhibited increased ER markers, highlighting IL-10’s role regulating muscle. Consequently, emerges as a therapeutic intervention to elevate adjust markers aging.

Language: Английский