Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 25 - 57
Published: Nov. 29, 2024
Language: Английский
Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2750 - 2750
Published: Nov. 30, 2024
The field of personalized medicine is undergoing a transformative shift through the integration multi-omics data, which mainly encompasses genomics, transcriptomics, proteomics, and metabolomics. This synergy allows for comprehensive understanding individual health by analyzing genetic, molecular, biochemical profiles. generation data enable more precise tailored therapeutic strategies, improving efficacy treatments reducing adverse effects. However, several challenges hinder full realization medicine. Key hurdles include complexity across different omics layers, need advanced computational tools, high cost generation. Additionally, issues related to privacy, standardization, robust validation in diverse populations remain significant obstacles. Looking ahead, future promises advancements technology methodologies that will address these challenges. Emerging innovations analytics, machine learning, high-throughput sequencing are expected enhance making accessible effective. Collaborative efforts among researchers, clinicians, industry stakeholders crucial overcoming fully harnessing potential individualized healthcare.
Language: Английский
Citations
18
Organogenesis, Journal Year: 2024, Volume and Issue: 20(1)
Published: Aug. 10, 2024
With the rapid development of field life sciences, traditional 2D cell culture and animal models have long been unable to meet urgent needs modern biomedical research new drug development. Establishing a generation experimental is great significance for deeply understanding human health disease processes, developing effective treatment measures. As well known, cycles, high risks, costs are "three mountains" facing drugs today. Organoids organ-on-chips technology can highly simulate reproduce physiological environment complex reactions in
Language: Английский
Citations
3
Postgraduate Medical Journal, Journal Year: 2024, Volume and Issue: 100(1189), P. 785 - 795
Published: May 25, 2024
Cardiovascular diseases (CVDs) present a significant global public health threat, contributing to substantial number of cases involving morbidity and mortality. Therefore, the early accurate detection CVDs plays an indispensable role in enhancing patient outcomes. Decades extensive research on electrocardiography at high frequencies have yielded wealth knowledge regarding alterations QRS complex during myocardial ischemia, as well methodologies assess quantify these changes. In recent years, analysis high-frequency (HF-QRS) components has emerged promising non-invasive approach for diagnosing various cardiovascular conditions. Alterations HF-QRS amplitude morphology demonstrated remarkable sensitivity diagnostic indicators often surpassing measures ST-T segment This comprehensive review aims provide intricate overview current advancements, challenges, prospects associated with field CVDs.
Language: Английский
Citations
1
Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 25 - 57
Published: Nov. 29, 2024
Language: Английский
Citations
0