AI-based opportunistic CT screening of incidental cardiovascular disease, osteoporosis, and sarcopenia: cost-effectiveness analysis

Abdominal Radiology, Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 20, 2023

Language: Английский

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Association of triglyceride glucose-related obesity indices with sarcopenia among U.S. adults: a cross-sectional study from the National Health and Nutrition Examination Survey

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 2, 2025

The triglyceride glucose (TyG) index-related obesity indices have been proposed as reliable indicators of insulin resistance. This study aims to investigate the association between TyG and sarcopenia well their potential a tool for screening sarcopenic patients. A cross-sectional was conducted involving 7,161 participants aged 18 above from National Health Nutrition Examination Survey. index indices, including glucose-body mass (TyG-BMI), glucose-waist circumference (TyG-WC), glucose-waist-to-height ratio (TyG-WHtR) were determined using standard formulas. appendicular skeletal muscle BMI used assess sarcopenia. relationship investigated restricted cubic spline analysis multivariate logistic regression analysis. diagnostic value -related compared receiver operating characteristic (ROC) curve. In fully adjusted model, positive correlation observed TyG-WHtR (for each one-unit increase in index: OR = 3.57, 95% CI: 2.71–4.71, P < 0.001). Additionally, analyses demonstrated significant predictor with highest odds ratio, reaching 12.50 (95% 6.13–25.70, 0.001) upper fourth quartile (Q4) first quartile, followed by TyG-BMI (Q4: 3.34; 1.92–5.80, TyG-WC 1.95; 1.04–3.68, RCS curve fitting indicated U-shaped diagnosis sarcopenia, an inflection point at 4.02. Furthermore, ROC analysis, AUC largest (0.79, ndex-related especially TyG-WHtR, shown be more effective identifying patients than alone.

Language: Английский

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Risk factors of stroke-related sarcopenia: a systematic review and meta-analysis

Frontiers in Aging, Journal Year: 2025, Volume and Issue: 6

Published: Jan. 31, 2025

Background The presence of sarcopenia at the time stroke may deteriorate rehabilitation and functional outcomes. There is no consensus on factors associated with stroke-related because previous studies produced inconsistent disputed results. Therefore, we screened possible risk by meta-analysis. Methods Studies published before March 2024 were searched through PubMed, Embase, Web Science, CINAHL, Cochrane Library, CNKI, Wan Fang, CBM, VIP library databases. Two researchers independently articles to extract information evaluate their quality. Meta-analysis was then performed using Revman 5.4 software determine significant for patients sarcopenia. Results A total 14 (n = 3,113) selected following that statistically in sarcopenia: Age (OR 1.04; 95% CI: 1.02, 1.06; P &lt; 0.0001), tube feeding 3.98; 2.12, 7.47; pre-stroke 1.84; 1.39, 2.43; atrial fibrillation 1.53; 1.15, 2.02; 0.003), NIHSS score 1.48; 1.21, 1.81; osteoporosis 1.801; 58, 2.04; 0.00001). BMI ( 0.71), FOIS 0.80), since 0.34), calf circumference reduction 0.48) not identified as or protective after 0.05). Conclusion Our results various which should be considered studied healthcare organizations professionals improve health patients. Systematic Review Registration PROSPERO, Identifier CRD42024545757.

Language: Английский

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Sex disparity in the association between alcohol consumption and sarcopenia: a population-based study

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Feb. 7, 2025

Background Previous studies have shown inconsistent findings regarding the association of alcohol consumption with sarcopenia. Therefore, this study comprehensively investigated sarcopenia in a nationally representative sample US adults. Methods This population-based included adults aged 18 years and older from National Health Nutrition Examination Survey (NHANES) III. Alcohol exposure was defined as daily intake, drinking history, number days per week, frequency binge month. Weighted logistic regressions were used to determine associations. Results Four cohorts selected NHANES III: cohort 1 ( n = 7,592), 2 12,060), 3 7,608), 4 7,649), corresponding categories In full model, risk significantly associated mild (odds ratio [OR]: 1.65; 95% confidence interval [CI]: 1.08–2.51), moderate (OR: 2.04; CI: 1.12–3.71), heavy drinkers 2.42; 1.17–4.97) compared nondrinkers. There an between development current 1.69; 1.12–2.56) but not former 1.21; 0.88–1.66). Compared nondrinkers, increased developing observed participants who consumed 2.36; 1.40–3.99) or &gt; 1.84; 1.10–3.07) those engaged for ≤1 day month 1.68; 1.09–2.60) 2.10; 1.10–4.01). Sensitivity analyses based on different definitions yielded similar results. Stratified revealed that these associations present females males. Conclusion intake all individuals, being primarily rather than

Language: Английский

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Effective Use of Plant Proteins for the Development of “New” Foods

Foods, Journal Year: 2022, Volume and Issue: 11(9), P. 1185 - 1185

Published: April 19, 2022

Diversity in our diet mirrors modern society. Affluent lifestyles and extended longevity have caused the prevalence of diabetes sarcopenia, which has led to increased demand low-carb, high-protein foods. Expansion global population Westernization Asian diets surged number meat eaters, eventually disrupted supply–demand balance meat. In contrast, some people do not eat for religious reasons or due veganism. With these multiple circumstances, society begun resort obtaining protein from plant sources rather than animal origins. This “protein shift” urges food researchers develop high-quality foods based on proteins. Meanwhile, patients with allergies, especially gluten-related ones, are reported be increasing. Additionally, growing popularity gluten-free demands development without using ingredients wheat origin. Besides, consumers prefer “clean-label” products expected contain fewer artificial compounds. These diversified spurred “new” view food-processing technologies as well selection primary ingredients. this short review, examples foodstuffs that achieved tremendous recent progress introduced: effective use realized high protein, bread/pasta. Basic manufacturing principles plant-based vegan cheese also been established. We will discuss strategy new better communication efficient

Language: Английский

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Exercise Programs Combined with Diet Supplementation Improve Body Composition and Physical Function in Older Adults with Sarcopenia: A Systematic Review

Nutrients, Journal Year: 2023, Volume and Issue: 15(8), P. 1998 - 1998

Published: April 21, 2023

Sarcopenia is a progressive and frequent syndrome among older adults highly related to physical inactivity malnutrition. Nowadays, it considered pathology that triggers multiple health complications associated with the loss of muscle mass, strength, autonomy, quality life. The objective present systematic review was evaluate effect exercise programs combined dietary supplementation on body composition as primary outcome. This carried out in accordance elements for planning by Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA), search performed Scopus, EBSCO, PubMed databases last 10 years. A total 16 studies met inclusion criteria were included this review. Regular resistance together daily essential amino acids or whey protein vitamin D improve maintenance gains appendiceal/skeletal mass lean sarcopenic adults. data suggest synergistic not only outcome, but also other variables such speed, stability, indicators registered PROSPERO, ID: CRD42022344284.

Language: Английский

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Vascular Impairment, Muscle Atrophy, and Cognitive Decline: Critical Age-Related Conditions

Biomedicines, Journal Year: 2024, Volume and Issue: 12(9), P. 2096 - 2096

Published: Sept. 13, 2024

The triad of vascular impairment, muscle atrophy, and cognitive decline represents critical age-related conditions that significantly impact health. Vascular impairment disrupts blood flow, precipitating the mass reduction seen in sarcopenia neuronal function characteristic neurodegeneration. Our limited understanding intricate relationships within this hinders accurate diagnosis effective treatment strategies. This review analyzes interrelated mechanisms contribute to these conditions, with a specific focus on oxidative stress, chronic inflammation, impaired nutrient delivery. aim is understand common pathways involved suggest comprehensive therapeutic approaches. dysfunctions hinder circulation transportation nutrients, resulting characterized by atrophy weakness. dysfunction have negative physical quality life. Neurodegenerative diseases exhibit comparable pathophysiological affect motor functions. Preventive approaches encompass lifestyle adjustments, addressing integrated therapies improving muscular well-being. Better links can refine strategies yield better patient outcomes. study emphasizes complex interplay between dysfunction, degeneration, decline, highlighting necessity for multidisciplinary Advances domain promise improved diagnostic accuracy, more options, enhanced preventive measures, all contributing higher life elderly population.

Language: Английский

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Nutrition in the prevention and treatment of skeletal muscle ageing and sarcopenia: a single nutrient, a whole food, and a whole diet approach

Proceedings of The Nutrition Society, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 16

Published: Oct. 17, 2024

Loss of skeletal muscle strength and mass (sarcopenia) is common in older adults associated with an increased risk disability, frailty premature death. Finding cost-effective prevention treatment strategies for sarcopenia the growing ageing population therefore great public health interest. Although nutrition considered important factor aetiology sarcopenia, its potential and/or still being evaluated. Nutrition research utilises three main approaches to understand muscle-nutrition relationships, evaluating: single nutrients, whole foods diet effects - both alone or combined exercise. Applying these approaches, we summarise recent evidence from qualitative quantitative syntheses findings observational intervention studies healthy adults, those sarcopenia. We consider protein supplements, (fruits vegetables) Mediterranean as exemplars. There some beneficial supplementation ≥ 0·8 g/kg body weight/d on when exercise training sarcopenic adults. In contrast, function (strength physical performance) inconclusive. reasonably consistent epidemiological suggesting benefits higher fruits vegetables consumption better performance. Similarly, adherence studies. However, are lacking. This review discusses how current may inform development preventive optimal nutritional policy aimed at combatting

Language: Английский

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Physical Activity, Sedentary Behavior, Fruit and Vegetable Consumption, and Sarcopenia in Older Chinese Adults: A Cross-Sectional Study

Nutrients, Journal Year: 2023, Volume and Issue: 15(15), P. 3417 - 3417

Published: Aug. 1, 2023

The purpose of this study was to investigate the association between moderate vigorous physical activity (MVPA), sedentary behavior, fruit and vegetable intake, risk sarcopenia among older Chinese adults. This cross-sectional enrolled 5418 adults who participated in Study on Global Aging Adult Health (SAGE). Participants reported information about their activity, dietary habits (fruit intake). Sarcopenia defined as presence low skeletal muscle mass either a slow gait speed or weak handgrip strength. A multiple logistic regression model employed determine relationship MVPA, sarcopenia. Only 32.63% participants met all three recommendations (for Compared with meeting none recommendations, associated lower (OR = 0.63, 95% CI 0.41-0.98). Moreover, recommendation for sufficient intake 0.69, 0.58-0.83), MVPA fruit/vegetable 0.67, 0.52-0.86), behavior 0.48-0.98) Our findings indicate that large representative sample adults, lifestyle protected against

Language: Английский

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Sarcopenia in Adults with Intellectual Disability: A Scoping Review Protocol to map and describe the existing research.

HRB Open Research, Journal Year: 2025, Volume and Issue: 8, P. 61 - 61

Published: May 16, 2025

Background There is a growing population of older persons with intellectual disability globally. Ageing in the general associated poorer health, and sarcopenia, age-related loss muscle mass function, debilitating consequences declining disability, adverse health outcomes hospitalisations. The sarcopenia adults likely to be even more complex given their pre-existing life-long disabilities. Identifying extent people will contribute development early screening prevention strategies, as well interventions address this treatable condition reduce long term complications. Consequently, aim scoping review map describe existing research on disability. Methods A methodology following Arksey O’Malley framework drawing guidelines from Joanna Briggs Institute conducted. question formulated based ‘’Population, Context, Concept’’ (PCC) relevant literature retrieved through comprehensive search strategy using CINAHL Ultimate (EBSCO), Medline EMBASE (Elsevier), PsycINFO Web Science (Clarivate) databases. All study designs included without time period restrictions an extensive grey also conducted, order capture broadly possible. Information extracted data extraction tool thematic analysis carried out categorize findings. results presented descriptive narrative form answer question. Conclusions This first conducted identify prevalence, diagnosis, factors implications These findings assist informing further guiding clinical practice.

Language: Английский

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