Biotechnology and Applied Biochemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 4, 2025
ABSTRACT
Lipases
are
indispensable
enzymes
with
a
wide
array
of
industrial
applications.
They
excel
at
breaking
down
triglycerides
and
essential
in
food
processing,
cleaning
agents,
biofuel
production,
environmental
remediation,
pharmaceuticals.
Microbial
sources,
particularly
bacteria
fungi,
dominate
lipase
production
due
to
their
high
efficiency,
cost‐effectiveness,
ability
target
specific
molecular
structures.
The
advent
genetic
engineering
has
further
revolutionized
by
enabling
the
development
tailored
that
meet
precise
needs.
As
eco‐friendly
biological
catalysts,
lipases
pivotal
advancing
sustainable
resource‐efficient
practices,
offering
significant
advantages
over
traditional
chemical
methods.
Their
role
innovation
spans
increased
reduced
impact,
enhanced
specificity
across
multiple
sectors.
These
qualities
establish
as
vital
tools
modern
biotechnology,
reinforcing
ongoing
significance
fostering
progress
stewardship.
Journal of Agricultural and Food Chemistry,
Journal Year:
2023,
Volume and Issue:
71(41), P. 14911 - 14930
Published: Oct. 6, 2023
With
the
development
of
artificial
intelligence
(AI),
tailoring
methods
for
enzyme
engineering
have
been
widely
expanded.
Additional
protocols
based
on
optimized
network
models
used
to
predict
and
optimize
lipase
production
as
well
properties,
namely,
catalytic
activity,
stability,
substrate
specificity.
Here,
different
algorithms
prediction
reforming
lipase,
focusing
its
modification
cases
AI,
are
reviewed
in
terms
both
their
advantages
disadvantages.
Different
neural
networks
coupled
with
various
usually
applied
maximum
yield
by
optimizing
external
cultivations
production,
while
one
part
is
molecule
variations
affecting
properties
lipase.
However,
few
studies
directly
utilized
AI
engineer
structure
enzyme,
a
set
research
gaps
needs
be
explored.
Additionally,
future
perspectives
application
enzymes,
including
engineering,
deduced
help
redesign
enzymes
reform
new
functional
biocatalysts.
This
review
provides
horizon
developing
effective
innovative
tools
facilitating
applications
food
industry
biomass
conversion.
