Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking DOI Open Access
Zahra Z. Farahbakhsh, Katherine M. Holleran, Jonathon Sens

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: March 17, 2024

Alcohol use disorder is marked by disrupted behavioral and emotional states which persist into abstinence. The enduring synaptic alterations that remain despite the absence of alcohol are interest for interventions to prevent relapse. Here, 28 male rhesus macaques underwent over 20 months drinking interspersed with three 30-day forced abstinence periods. After last period, we paired direct sub-second dopamine monitoring via

Language: Английский

Genetics and epigenetics approaches as a path to the future of addiction science DOI Open Access
Anne E. West, Jeremy J. Day

Molecular and Cellular Neuroscience, Journal Year: 2023, Volume and Issue: 127, P. 103898 - 103898

Published: Aug. 31, 2023

Language: Английский

Citations

1
Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking DOI Open Access
Zahra Z. Farahbakhsh, Katherine M. Holleran, Jonathon Sens

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: March 17, 2024

Alcohol use disorder is marked by disrupted behavioral and emotional states which persist into abstinence. The enduring synaptic alterations that remain despite the absence of alcohol are interest for interventions to prevent relapse. Here, 28 male rhesus macaques underwent over 20 months drinking interspersed with three 30-day forced abstinence periods. After last period, we paired direct sub-second dopamine monitoring via

Language: Английский

Citations

0