Low HDL cholesterol levels in women and hypertriglyceridemia in men: predictors of MASLD onset in individuals without steatosis

Journal of Gastroenterology, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Language: Английский

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Effect of Simvastatin Combined with Photobiomodulation Therapy on Orthodontic Tooth Movement and the Expression of Metalloproteinases and Inhibitors - An Experimental Study

Lasers in Medical Science, Journal Year: 2025, Volume and Issue: 40(1)

Published: April 14, 2025

Language: Английский

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A Phase I Study to Evaluate the Relative Bioavailability, Pharmacodynamics, and Safety of a Single Subcutaneous Injection of Recaticimab at Three Different Sites in Healthy Chinese Subjects

European Journal of Drug Metabolism and Pharmacokinetics, Journal Year: 2025, Volume and Issue: unknown

Published: April 19, 2025

Language: Английский

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Assessing Omega-3 Therapy and Its Cardiovascular Benefits: What About Icosapent Ethyl? A Systematic Review and Meta-Analysis

Pharmaceuticals, Journal Year: 2025, Volume and Issue: 18(4), P. 601 - 601

Published: April 20, 2025

Background: Lipid-lowering therapies are an option for stabilizing lipid levels. Icosapent ethyl (IPE) is a highly purified formulation of eicosapentaenoic acid, which can reduce action, improve plaque stabilization, platelet aggregation, lower TG, and prevent cardiovascular events. IPE frequently used with statins to manage elevated TG However, the evidence on as lipid-lowering agent limited, no updated systematic review meta-analysis have been published considering recent advancements in field newly studies. Therefore, we aim fill this gap. Methods: We PRISMA guidelines PICO (Population, Intervention, Comparison, Outcome) framework conduct review, aiming answer question, “Can benefit patients at risk?” GRADE was evaluate levels adhere highest criteria. Results: Predominantly, evaluated population presented between ≥135 mg/dL 500 LDL-C >40 ≤100 mg/dL. The included studies showed reduction decrease It means that, according our analysis, has effective lowering blood levels, including reducing death events, such non-fatal stroke or hospitalization unstable angina. it worth noting that these results were primarily from undergoing statin therapy. According meta-analysis, may not be considered drug, limited action associated its use evident quantitative results. caution necessary, only two suitable inclusion due differing outcomes analyzed samples. Conclusions: Despite synthesis, possesses anti-inflammatory, anti-thrombotic, anti-atherogenic properties, related protection. Based studies, promising therapy atherosclerotic disease conjunction other therapies, particularly statins, extremely high limitations reviewed include small sample sizes, varying outcomes, duration interventions. Future clinical trials similar intervention durations must designed, meta-analyses following years fully assess effects protector drug.

Language: Английский

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Extraction, purification, structural characterization, and bioactivities of Radix Aconiti Lateralis Preparata (Fuzi) polysaccharides: A review

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 292, P. 139285 - 139285

Published: Dec. 28, 2024

Language: Английский

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The Distribution Pattern of Traditional Chinese Medicine Syndromes in Patients with Hyperlipidemia

Journal of Biosciences and Medicines, Journal Year: 2024, Volume and Issue: 12(09), P. 173 - 182

Published: Jan. 1, 2024

Language: Английский

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