BMC Geriatrics, Journal Year: 2024, Volume and Issue: 24(1)
Published: Oct. 30, 2024
Sarcopenia has been shown to be an important condition with the ability predict negative health outcomes, especially in hospitalized older adults; hence, its accurate identification role prognosis of patients.
Language: Английский
Metabolism, Journal Year: 2024, Volume and Issue: 160, P. 155994 - 155994
Published: Aug. 6, 2024
Language: Английский
Citations
4
Nutrients, Journal Year: 2025, Volume and Issue: 17(1), P. 171 - 171
Published: Jan. 2, 2025
Background: Nutritional risks in older adults, such as malnutrition and sarcopenia, are often underdiagnosed. Screening practices frequently rely on Unplanned Weight Loss (UPWL), potentially overlooking at-risk individuals. This study aims to assess the prevalence of nutritional risk, identified by UPWL across different body mass index categories a nursing home (NH) population. Methods: Cross-sectional data were collected from an NH Danish municipality, including those all self-reliant participants who consented excluding terminally ill adults. Data age, sex, height, weight, chronic diseases extracted medical records. risk was assessed using two markers: ≥1 kg during last six months muscle strength via modified 30 s chair stand test marker sarcopenia. An ANOVA Fisher’s Exact Test used differences, followed post hoc Tukey test. Results: In our adults (n = 93, mean age 83.2 ± 9.12 years, 63% female), 17 individuals (19%) had UPWL, 27 (29%) Among with obesity, twelve (48%) but only (8%) UPWL. contrast, seven (21%) normal weight while eleven (33%) experienced Conclusions: Older NHs at varies significantly depending whether or sarcopenia markers applied for categorization. Sarcopenia highest obesity group, suggesting need integrating quantity assessments into community care identify better.
Language: Английский
Citations
0
Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)
Published: Feb. 8, 2025
In previous studies, several inflammatory biomarkers derived from complete blood cell counts (CBC), such as systemic immune inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and non‑high‑density lipoprotein cholesterol to high‑density (NHHR) have been identified predictors of sarcopenia. However, whether Monocyte High-Density Lipoprotein Cholesterol Ratio (MHR) can predict the development sarcopenia has not yet established. The research first attempts investigate association between MHR low muscle mass compare predictive abilities MHR, SII, NLR, NHHR for risk. study comprised 10,321 participants aged 20 years above United States. Multiple logistic regression was performed explore ln-transformed mass. Additionally, AUC values ROC curves were used assess effectiveness ln other markers (ln NHHR, + NLR). bootstrap estimated 95% Cl shown with AUC. fully adjusted model, NLR positively associated SII: OR = 1.59 [1.37-1.84]; NLR: 1.35 [1.13-1.60]; NHHR: 1.49[1.27-1.75]; MHR: 1.98 [1.68-2.33]; 1.61 [1.46-1.79]; 1.42 [1.29-1.56]; 1.58 [1.41-1.78]). Compared lowest quartile higher quartiles significantly increased odds (P trend < 0.0001). analysis, SII had a value than indicators (AUC 0.608). Ln-transformed outperforms in predicting
Language: Английский
Citations
0
Metabolism, Journal Year: 2025, Volume and Issue: 169, P. 156272 - 156272
Published: April 19, 2025
Language: Английский
Citations
0
Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12
Published: June 6, 2024
Background In 2022, the European Society for Clinical Nutrition and Metabolism (ESPEN) Association Study of Obesity (EASO) launched a consensus on diagnostic methods sarcopenic obesity (SO). The study aimed to identify prevalence agreement SO using different in cohort subjects from West China aged at least 50 years old. Methods A large multi-ethnic sample 4,155 participants Health Aging Trend (WCHAT) was analyzed. defined according newly published ESPEN/EASO. Furthermore, diagnosed as combination sarcopenia obesity. criteria established by Asian Working Group Sarcopenia 2019 (AWGS2019) were used define sarcopenia. four widely indicators: percent body fat (PBF), visceral area (VFA), waist circumference (WC), mass index (BMI). Cohen’s kappa analyze above five methods. Results total part study, including 1,499 men (63.76 ± 8.23 years) 2,656 women (61.61 8.20 years). 0.63–7.22% with diagnosis poor-to-good (κ: 0.06–0.67). ESPEN/EASO had poorest other 0.06–0.32). AWGS+VFA best AWGS+WC (κ = 0.67), AWGS+ PBF 0.32). Conclusion varies considerably between has highest rate SO, whereas AWGS+BMI lowest. relatively good methods, while poor agreement. AWGS+PBF may be suitable alternative 2022
Language: Английский
Citations
3
Thoracic Cancer, Journal Year: 2024, Volume and Issue: 15(31), P. 2248 - 2259
Published: Sept. 22, 2024
Abstract Background Limited information is available regarding the impact of sarcopenia on prognosis antiangiogenic therapy in individuals with advanced non‐small cell lung cancer (NSCLC). This study primarily sought to examine prognostic significance NSCLC undergoing therapy. Methods We retrospectively enrolled all patients who met inclusion and exclusion criteria from 2019 2021 at Nantong University Hospital. Patients were grouped according presence or absence sarcopenia. After propensity score matching (PSM), progression‐free survival (PFS), overall (OS), adverse event rates compared between two groups. Factors associated screened using univariate multivariate analyses. Results A total 267 included, a 201 matched baseline after PSM (77 group 124 non‐sarcopenia group). The had lower PFS ( p = 0.043) OS 0.011) than higher incidence events 0.044). Multivariate analysis suggested that an independent risk factor for receiving therapies 0.009). subgroup analyses showed some differences populations different characteristics. Conclusion comorbid exhibit worse when treated therapy, preventing ameliorating may lead better outcomes NSCLC.
Language: Английский
Citations
2
Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 13(1), P. 196 - 196
Published: Dec. 29, 2023
The accuracy of multi-frequency (MF) bioelectrical impedance analysis (BIA) to estimate low muscle mass in older hospitalized patients remains unclear. This study aimed describe the ability MF-BIA identify as proposed by Global Leadership Initiative on Malnutrition (GLIM) and European Working Group Sarcopenia Older People (EWGSOP-2) examine association between mass, dehydration, malnutrition, poor appetite patients. In this prospective exploratory cohort study, was estimated with against dual-energy X-ray absorptiometry (DXA) 42 adults (≥65 years). primary variable for appendicular skeletal (ASM), secondary variables were index (ASMI) fat-free (FFMI). Cut-off values based recommendations GLIM EWGSOP-2. evaluated DXA absolute mean bias, limits agreement (LOA), (5% 10% levels). Agreement sensitivity, specificity, negative predictive value (NPV), positive (PPV). visually examined boxplots. overestimated ASM a bias 0.63 kg (CI: −0.20:1.46, LOA: −4.61:5.87). measures showed sensitivity 86%, specificity 94%, PPV 75% NPV 97%. Boxplots indicate that is lower malnutrition. not observed appetite. We tendency toward higher dehydration. Estimation should be interpreted caution, but might
Language: Английский
Citations
6
Journal of Hepatocellular Carcinoma, Journal Year: 2023, Volume and Issue: Volume 10, P. 1367 - 1377
Published: Aug. 1, 2023
Recent research has suggested that sarcopenia may have an impact on postoperative outcomes. The number of hepatocellular carcinoma (HCC) patients with metabolic dysfunction-associated fatty liver disease (MAFLD) increased significantly over time. main objective this study was to investigate the prognosis HCC MAFLD after hepatectomy.A multivariate Cox proportional hazards model and a propensity score matching (PSM) analysis were conducted ensure baseline characteristics similar. Kaplan‒Meier survival curves used compare two groups.This involved 112 undergoing hepatectomy. Sarcopenia indicated as risk factor for both recurrence-free (RFS) overall (OS) in (p=0.002 0.022, respectively). After conducting PSM analysis, curve revealed significant differences RFS OS between groups (p=0.0002 p=0.0047, All results showed had poor hepatectomy.In summary, our suggests might be who underwent hepatectomy through analysis. imperils rates finding can guide clinical decision-making. For patients, preventing or treating potentially improve outcomes MAFLD.
Language: Английский
Citations
5
Metabolism, Journal Year: 2023, Volume and Issue: 150, P. 155717 - 155717
Published: Nov. 3, 2023
Language: Английский
Citations
5
Academic Radiology, Journal Year: 2023, Volume and Issue: 31(4), P. 1272 - 1283
Published: Dec. 8, 2023
Language: Английский
Citations
4