Cited by Editorial overview: emerging avenues in antimicrobial research

Actinomycetes: Treasure Trove for Discovering Novel Antibiotic Candidates DOI

Rui Yi,

Yutong Shi,

Xun Cao

et al.

European Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 117317 - 117317

Published: Jan. 1, 2025

Language: Английский

Citations

Unlocking the potential of Streptomyces species as promising biological control agents against phytonematodes DOI

Mani Jayakumar, Dineshkumar Kandasamy, R. Thamizh Vendan

et al.

Physiological and Molecular Plant Pathology, Journal Year: 2024, Volume and Issue: 134, P. 102465 - 102465

Published: Nov. 1, 2024

Language: Английский

Citations

Effect of polyethylene microplastics on tebuconazole bioaccumulation, oxidative stress, and intestinal bacterial community in earthworms DOI

Xiaoqian Qiu,

Diwen Yang,

Leixin Yu

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136056 - 136056

Published: Oct. 10, 2024

Language: Английский

Citations

The genus Nocardia as a source of new antimicrobials DOI

Napawit Nonthakaew,

Liam K. R. Sharkey, Sacha J. Pidot

et al.

npj Antimicrobials and Resistance, Journal Year: 2025, Volume and Issue: 3(1)

Published: Jan. 25, 2025

Abstract The genus Nocardia comprises over 130 species of soil-dwelling actinomycetes, many which are opportunistic pathogens. Beyond their pathogenicity, exhibits significant biosynthetic potential, producing an array diverse antimicrobial secondary metabolites. This review highlights notable examples these compounds and explores modern approaches to unlocking untapped potential. As a relatively underexplored genus, represents promising source for new antibiotics combat the growing resistance crisis.

Language: Английский

Citations

Unveiling the Diversity of Culturable Microbes from the Underexplored Mingyong Glacier Landscape: A Roadmap for Leveraging the Potential of Actinomycetota DOI

Pachaiyappan Saravana Kumar,

Changjun Xiang,

Lihan Zhang

et al.

Indian Journal of Microbiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 27, 2025

Language: Английский

Citations

PPtase-activated production of borrelidin from extremophilic actinobacteria against multidrug-resistant cotton pathogen Verticillium dahliae DOI

Fei Zhang,

Xingzhi Jiao,

Yibo Wu

et al.

The Journal of Antibiotics, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

Language: Английский

Citations

Taxonomic Identification, Complete Genome Sequencing, and In Silico Genome Mining of the Actinobacterium Lentzea sp. JNUCC 0626 Isolated from Jeju Gotjawal DOI

Kyung‐A Hyun, Kyung-Hwan Boo, Chang‐Gu Hyun

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 70(1), P. 8 - 8

Published: Feb. 7, 2025

In our previous study, Lentzea sp. JNUCC 0626 was isolated from Hwasun Gotjawal on Jeju Island, and its melanogenic effects were confirmed in B16F10 melanoma cells through the identification of 1-acetyl-β-carboline. this we conducted a comprehensive taxonomic characterization 0626, including enzymatic activities, carbohydrate metabolism, growth conditions, cellular composition. Major fatty acids identified iso-C16:0, iso-C15:0, C15:0 anteiso, with polar lipids such as diphosphatidylglycerol, phosphatidylethanolamine, several unidentified lipids. Ubiquinone Q-9 determined predominant respiratory quinone. Enzymatic activity analysis (API ZYM) showed alkaline phosphatase, esterase (C4), lipase (C8), leucine arylamidase while metabolism 50CHB) indicated acid production esculin alone. Complete genome sequencing revealed 10,602,950 bp linear chromosome 177,940 plasmid. This plasmid encodes essential plasmid-related genes, Type IV secretion system ParA proteins critical for transfer stability. These findings suggest that could be utilized developing host–vector systems to facilitate combinatorial biosynthesis novel bioactive compounds. Comparative genomic pudingi CGMCC 4.7319 closest relative, but significant genetic divergence (dDDH 46.7%, ANI 88.02%) strongly supports classification species. AntiSMASH 34 biosynthetic gene clusters (BGCs), highlighting strain’s capacity produce diverse Finally, extract exhibited concentration-dependent NO inhibition LPS-stimulated RAW 264.7 cells, demonstrating anti-inflammatory activity. suggests secondary metabolites inferred may contribute these observed bioactivities.

Language: Английский

Citations

Geliboluols A–D: Kaurane-Type Diterpenoids from the Marine-Derived Rare Actinomycete Actinomadura geliboluensis DOI

Chang-Su Heo,

Jong Soon Kang,

Jeong-Wook Yang

et al.

Marine Drugs, Journal Year: 2025, Volume and Issue: 23(2), P. 78 - 78

Published: Feb. 10, 2025

Four new kaurane-type diterpenoids, geliboluols A-D (1-4), along with one known analog (5), were isolated from the culture broth of marine-derived rare actinomycete Actinomadura geliboluensis. The structures compounds 1-4 determined by spectroscopic analysis (HR-ESIMS, 1D, and 2D NMR), MPA method, comparing their optical rotation values those in literature. evaluated for cytotoxicity against seven blood cancer cell lines a CellTiter-Glo (CTG) assay six solid sulforhodamine B (SRB) assay. Among compounds, compound 4 exhibited moderate cytotoxic activity some lines, GI50 ranging 2.59 to 19.64 µM, 4.34 7.23 µM.

Language: Английский

Citations

Intensive cultivation of whiteleg shrimp (Litopenaeus vannamei) under biofloc condition in land-based ponds DOI

Jing Lu,

Huan Ren,

Wujie Xu

et al.

Aquaculture Reports, Journal Year: 2025, Volume and Issue: 41, P. 102690 - 102690

Published: Feb. 15, 2025

Language: Английский

Citations

Genome mining and metabolite profiling illuminate the taxonomy status and the cytotoxic activity of a mangrove-derived Microbacterium alkaliflavum sp. nov DOI

Wenjin Hu,

Lixian Deng,

Yiying Huang

et al.

BMC Microbiology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 28, 2025

Language: Английский

Citations