Cutting-edge tools for unveiling the dynamics of plasmid–host interactions
Qiu Yang,
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Jianmei Gao,
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Shaolin Zhou
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et al.
Trends in Microbiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Language: Английский
Human microbiome acquisition and transmission
Nature Reviews Microbiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 21, 2025
Language: Английский
Real-world antibiotic utilization during pregnancy in Italy: a multiregional retrospective population-based study
BMC Pregnancy and Childbirth,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: April 23, 2025
Language: Английский
Editorial overview: A critical crossroad in microbiome research: Where do we go?
Current Opinion in Microbiology,
Journal Year:
2024,
Volume and Issue:
78, P. 102438 - 102438
Published: Feb. 20, 2024
Language: Английский
Prevalence and Distribution of Geo-Helminths and Intestinal Protozoa Infections among School-Going Children in Nyeri County, Kenya
African Journal of Empirical Research,
Journal Year:
2024,
Volume and Issue:
5(2), P. 787 - 799
Published: June 18, 2024
The
goal
of
this
study
was
to
determine
how
common
and
widespread
geo-helminths,
STH,
intestinal
protozoa
infections
are
in
the
Mathira
constituency
Nyeri
County,
Kenya.
aimed
prevalence
geohelminths
protozoa,
as
well
distribution
STH
school-going
children.
Cochran
formulae
guided
design
a
cross-sectional
on
population
174
children,
yielding
complete
data
for
164
them.
social
determinants
health
model
study.
A
structured
questionnaire
applied
collection
establish
demographic
characteristics
participants
identified
three
primary
schools
site.
They
were
examined
by
quantitative
Kato-Katz
technique
formal
ether
concentration
techniques
infection.
Statistical
analysis
done
using
R
Studio
risk
ratio.
Findings
showed
that
56
samples
Kihuro
school,
12
(21.4%)
6
(10.7%)
positive
protozoan
infections.
Similarly,
33%
children
Gathuini
school
found
be
infections,
while
13%
infected
with
STH.
In
Gikumbo
20.4%
parasites,
compared
However,
there
variation
infection
based
gender
across
selected
sites.
Children
0.12
times
more
at
0.3
higher
than
school.
0.46
0.1
0.26
implying
they
prone
concluded
age
students
had
no
statistical
significance.
recommended
government
institutions
non-governmental
organizations
should
intervene
undertake
adequate
control
measures
against
geo-helminth
parasites
making
sure
is
access
safe
water
improved
sanitation
area.
Moreover,
education
programs
intensified
area
beyond
raise
awareness
geo-helminths
infection,
means
transmission
measures,
improvement
hygiene
practices
both
parents.
Language: Английский
Dynamics and determinants of the gut mobilome in early life
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 7, 2024
Abstract
As
mobile
genetic
elements
(MGE)
are
critical
yet
understudied
determinants
of
gut
microbiome
composition,
we
characterized
the
virome
and
plasmidome
in
195
samples
from
28
mother–infant
dyads
delivered
by
caesarean
section.
Infant
mobilome
increased
richness
over
first
6
postnatal
weeks,
demonstrating
high
individual-specificity
temporal
stability,
establishing
a
personal
persistent
mobilome.
Formula-fed
infants
exhibited
greater
than
breastfed
infants,
with
plasmid
composition
influenced
antibiotic
exposure
birth
weight.
Plasmids
constituted
significant
reservoir
resistance
genes
(ARG),
around
5%
infant
taxonomic
units
carrying
ARG.
Notably,
ARG
profiles
did
not
differ
at
birth.
We
found
that
sharing
viral
strains
primarily
occurred
after
months
age.
Overall,
our
integrative
analysis
offers
novel
insights
into
dynamics,
modulation,
origin,
clinical
implications
MGE
developing
microbiome.
Language: Английский