
BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)
Published: May 2, 2025
Oral complications following cancer treatment are a challenging issue for oncologists. Several studies have demonstrated the efficacy of biotics in prevention and oral thyroid head neck cancers. Following PRISMA criteria, systematic review meta-analysis included on efficacy, safety, dosage, duration was performed. A total 12 randomized controlled trials 885 individuals were this meta-analysis. Our analysis showed that had slight but insignificant effect incidence mucositis (Risk ratio (RR) = 0.90, 95% CI [0.79, 1.03]), significant impact reducing severity (RR 0.62, [0.48, 0.80]). Biotics also developing xerostomia Head (HNC) patients. Subgroup Bifidobacterium-containing products more effective than other blends. findings safe HNC patients suffering from complications.
Language: Английский