Characterization of glycogen-related glycoside hydrolase glgX and glgB from Klebsiella pneumoniae and their roles in biofilm formation and virulence DOI Creative Commons
Xinyue Liu, Jialin Li, Ruibing Wu

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: Dec. 18, 2024

Glycogen is a polymer used by bacteria to store excess glucose, playing crucial role in bacterial growth, stress resistance, biofilm formation, and virulence. In bacteria, the glycoside hydrolase family 13 protein are involved synthesis metabolism of glycogen, respectively. The absence these enzymes leads changes glycogen content, thereby affecting growth strain. To date, research on roles glycogen-related genes phenotypes

Language: Английский

Combination of antimicrobial peptide and clinical antibiotic shows enhanced potency toward Acinetobacter baumannii infection DOI
Jih‐Chao Yeh, Chin-Hao Yang,

Prakash Kishore Hazam

et al.

European Journal of Pharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 177683 - 177683

Published: April 1, 2025

Language: Английский

Citations

0
Multi-target anti-MRSA mechanism and antibiotic synergistic effect of marine alkaloid Ascomylactam A in vitro and in vivo against clinical MRSA strains DOI

King‐Chuan Wu,

Fei-Hua Yao,

Xiaopu Ren

et al.

Biochemical Pharmacology, Journal Year: 2024, Volume and Issue: 232, P. 116697 - 116697

Published: Dec. 4, 2024

Language: Английский

Citations

1
Antibacterial Effects of Paeonia lactiflora Extract on Oral Microcosm Biofilms DOI Creative Commons
Ji Won Lim, Min-Kyung Kang, Hee‐Eun Kim

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(23), P. 11290 - 11290

Published: Dec. 3, 2024

The aim of this study was to evaluate the antibacterial effects Paeonia lactiflora (PL) extract on oral microcosm biofilms and determine its usefulness as a natural alternative current antimicrobial agents. Oral were cultivated hydroxyapatite disks using human saliva for 2 days, following which they treated with 1.5 mL distilled water (DW), 30 μg/mL PL extract, or 0.12% chlorhexidine gluconate (CHX) once daily 3 days. Antibacterial assessed by measuring red fluorescence intensity (RatioR/G), bacterial viability (RatioG/G+R), aciduric counts. RatioR/G evaluated quantitative light-induced digital imaging. RatioG/G+R in group 0.94-fold 0.73-fold lower than those DW (p < 0.001 p = 0.011, respectively) comparable CHX 0.356 0.964, respectively). Aciduric counts 0.97-fold 0.001), no significant difference from 0.892). Thus, effect that CHX; suggests potential managing biofilm-associated diseases.

Language: Английский

Citations

0
Characterization of glycogen-related glycoside hydrolase glgX and glgB from Klebsiella pneumoniae and their roles in biofilm formation and virulence DOI Creative Commons
Xinyue Liu, Jialin Li, Ruibing Wu

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: Dec. 18, 2024

Glycogen is a polymer used by bacteria to store excess glucose, playing crucial role in bacterial growth, stress resistance, biofilm formation, and virulence. In bacteria, the glycoside hydrolase family 13 protein are involved synthesis metabolism of glycogen, respectively. The absence these enzymes leads changes glycogen content, thereby affecting growth strain. To date, research on roles glycogen-related genes phenotypes

Language: Английский

Citations

0