Co-housing with Tibetan chickens improved the resistance of Arbor Acres chickens to Salmonella enterica serovar Enteritidis infection by altering their gut microbiota composition

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology, Journal Year: 2025, Volume and Issue: 16(1)

Published: Jan. 3, 2025

Abstract Background Salmonella enterica serovar Enteritidis ( S . Enteritidis) is a global foodborne pathogen that poses significant threat to human health, with poultry being the primary reservoir host. Therefore, addressing infections in crucial protect health and industry. In this study, we investigated effect of co-housing Arbor Acres (AA) chickens, commercial breed susceptible Enteritidis, Tibetan local resistant infection, on resistance latter pathogen. Results Ninety-six 1-day-old chickens 96 AA were divided into chicken housed alone group n = 48), an co-housed (48 birds from each for 2 cages). All provided same diet, experimental period lasted 14 d. At d 7, all infected samples collected at 1-, 3-, 7-day-post-infection. We found body weight significantly increased when 1- 3-day-post-infection P < 0.05). addition, cecal load was reduced 7-day-post-infection Furthermore, inflammatory response decreased, as evidenced by decreased expression pro-inflammatory cytokines NOS2 , TNF-α IL-8 IL-1β IFN-γ their tonsils Co-housing height villi number goblet cells 0.05), well claudin-1 tight junction protein, jejunum chickens. Further analysis revealed altered gut microbiota composition chickens; specifically, relative abundances harmful microbes, such Intestinimonas Oscillibacter Tuzzerella Anaerotruncus Paludicola, Anaerofilum Conclusions Our findings indicate enhanced infection without compromising This study provides novel approach control practical production.

Language: Английский

Synergistic antimicrobial activity of alpha-linolenic acid in combination with tetracycline or florfenicol against multidrug-resistant Salmonella typhimurium

Microbial Pathogenesis, Journal Year: 2024, Volume and Issue: unknown, P. 106982 - 106982

Published: Sept. 1, 2024

Language: Английский