Nose-on-Chip Nanobiosensors for Early Detection of Lung Cancer Breath Biomarkers
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(9), P. 4469 - 4494
Published: Sept. 9, 2024
Lung
cancer
remains
a
global
health
concern,
demanding
the
development
of
noninvasive,
prompt,
selective,
and
point-of-care
diagnostic
tools.
Correspondingly,
breath
analysis
using
nanobiosensors
has
emerged
as
promising
noninvasive
nose-on-chip
technique
for
early
detection
lung
through
monitoring
diversified
biomarkers
such
volatile
organic
compounds/gases
in
exhaled
breath.
This
comprehensive
review
summarizes
state-of-the-art
breath-based
diagnosis
employing
chemiresistive-module
supported
by
theoretical
findings.
It
unveils
fundamental
mechanisms
biological
basis
biomarker
generation
associated
with
cancer,
technological
advancements,
clinical
implementation
nanobiosensor-based
analysis.
explores
merits,
challenges,
potential
alternate
solutions
implementing
these
settings,
including
standardization,
biocompatibility/toxicity
analysis,
green
sustainable
technologies,
life-cycle
assessment,
scheming
regulatory
modalities.
highlights
nanobiosensors'
role
facilitating
precise,
real-time,
on-site
leading
to
improved
patient
outcomes,
enhanced
management,
remote
personalized
monitoring.
Additionally,
integrating
biosensors
artificial
intelligence,
machine
learning,
Internet-of-things,
bioinformatics,
omics
technologies
is
discussed,
providing
insights
into
prospects
intelligent
sniffing
nanobiosensors.
Overall,
this
consolidates
knowledge
on
breathomic
biosensor-based
screening,
shedding
light
its
significance
applications
advancing
medical
diagnostics
reduce
burden
hospitals
save
human
lives.
Language: Английский
Recent advances of surface plasmon resonance sensors based on metal-organic frameworks
Talanta,
Journal Year:
2025,
Volume and Issue:
unknown, P. 128008 - 128008
Published: March 1, 2025
Language: Английский
Collaborative integration of SERS and QCM sensing for label-free multi-component gas detection
Talanta,
Journal Year:
2025,
Volume and Issue:
286, P. 127509 - 127509
Published: Jan. 1, 2025
Language: Английский
Flexible Optical Fiber Sensor for Non‐Invasive Continuous Monitoring of Human Physiological Signals
Small Methods,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 2, 2025
Abstract
With
increasing
health
awareness,
monitoring
human
physiological
signals
for
status
and
disease
prevention
has
become
crucial.
Non‐invasive
flexible
wearable
devices
address
issues
like
invasiveness,
inconvenience,
size,
continuous
challenges
in
traditional
devices.
Among
sensors,
optical
fiber
sensors
(OFSs)
stand
out
due
to
their
excellent
biocompatibility,
anti‐electromagnetic
interference
capabilities,
ability
monitor
multiple
simultaneously.
This
paper
reviews
the
application
of
sensing
technology
(OFST)
lung
function,
cardiovascular
body
parameters,
motor
various
signals.
It
emphasizes
importance
personal
management,
clinical
settings,
sports
training,
emergency
response.
The
review
discusses
OFST
signal
envisions
its
significant
potential
future
development.
underscores
constant
highlights
advantages
prospects
sensing.
Innovations
OFS
non‐invasive
hold
profound
implications
materials
science,
technology,
biomedicine.
Language: Английский
Influence of Surface Treatments on the Electrochemical Performance of Lab-Made 3D-Printed Electrodes
Analytica—A Journal of Analytical Chemistry and Chemical Analysis,
Journal Year:
2025,
Volume and Issue:
6(1), P. 9 - 9
Published: March 4, 2025
This
study
investigated
the
effect
of
surface
treatments
on
electrochemical
performance
3D-printed
electrodes
for
versatile
applications.
The
conductive
filament
was
obtained
from
a
mixture
polylactic
acid
(PLA)
and
carbon
black
(CB)
at
7:3
ratio
(PLA/CB)
dispersed
in
acetic
dichloroethane
(3:1)
medium.
used
were
HNO3,
NaOH,
DMF
(immersion
30,
15
min,
respectively),
activation
(amperometry
150
s,
1.8
V).
In
general,
allow
greater
exposure
material
active
sites
present
sensor
surface.
confirmed
using
cyclic
voltammetry
impedance
spectroscopy.
analyses
conducted
with
0.10
M
KCl
solution
containing
redox
pair
ferricyanide/ferrocyanide
5.00
mmol
L−1.
Based
results
obtained,
electroactive
area,
kinetic
constant
resistance
to
electron
transfer
determined
each
treatment.
treatment
basic
medium
stood
out
as
that
most
appropriate
device
this
work.
also
tested
its
potential
analysis
acetaminophen,
demonstrating
satisfactory
permitting
application
3D-SBasic
acetaminophen.
Language: Английский
Rational Design and Application of Breath Sensors for Healthcare Monitoring
Kai Liu,
No information about this author
Min Lin,
No information about this author
Zhihui Zhao
No information about this author
et al.
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 31, 2024
Biomarkers
contained
in
human
exhaled
breath
are
closely
related
to
certain
diseases.
As
a
noninvasive,
portable,
and
efficient
health
diagnosis
method,
the
sensor
has
received
considerable
attention
recent
years
for
early
disease
screening
prevention
due
its
user-friendly
easy-accessible
features.
Although
some
key
challenges
have
been
addressed,
capability
precisely
monitor
specific
biomarkers
of
interest
physiological
relevance
metrics
is
still
be
ascertained.
In
this
context,
we
analyzed
rational
design
advance
sensors
healthcare
monitoring.
This
review
begins
with
an
introduction
their
sensing
technologies,
such
as
chemoresistive,
humidity-sensitive,
electrochemical,
colorimetric
principles.
Then,
systematic
overview
emerging
applications
screening,
drunk
driving
inspection,
apnea
monitoring,
condensate
analysis
demonstrated.
Finally,
discuss
opportunities
noninvasive
With
ongoing
research
efforts,
continuous
breakthrough
attractive
foreseeable
future.
Language: Английский