Graphene and Its Derivatives for Electrochemical Sensing

Sensors, Journal Year: 2025, Volume and Issue: 25(7), P. 1993 - 1993

Published: March 22, 2025

As a typical two-dimensional material, graphene and its derivatives exhibit many excellent properties, such as large specific surface area, electrical stability. Along with derivatives, particularly oxide (GO) reduced (rGO), materials have been studied in various fields due to the presence of aromatic ring, free π-π electron reactive functional groups. This review focuses firstly on synthesis methods along their followed by discussion applications served units electrochemical sensing. Finally, this describes challenges, strategies, outlooks future developments.

Language: Английский

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Highly sensitive electrochemical immunosensor based on methylene blue-reduced graphene oxide nanocomposites as signal probes for IL-6 detection in gingival crevicular fluid samples

Frontiers in Chemistry, Journal Year: 2025, Volume and Issue: 13

Published: April 2, 2025

As an important inflammatory cytokine, interleukin-6 (IL-6) can mediate the entire pathological process of periodontitis and is closely associated with degree inflammation. Therefore, it critical to develop convenient quantitative methods for monitoring IL-6 quantity in gingival crevicular fluid. In this study, methylene blue (MB)-decorated reduced graphene oxide (rGO) employed as signal probe further support antibody-enabling specific recognition IL-6. Due π-π stacking electrostatic interactions, rGO-MB nanocomposites be stably obtained. rGO good conductivity large surface area characteristics promotes redox signals MB on glassy carbon electrode (GCE). addition, through simple situ self-polymerization dopamine, polydopamine (PDA) obtained not only directly used a biological crosslinking agent covalent immobilization anti-IL-6 antibody but also regarded protective layer enhance stability GCE surface. Such designed PDA/rGO-MB/GCE-based immunosensor enables binding produces decreased electrochemical MB, realizing selective sensitive measurement Consequently, our fabricated has excellent linear relationship ranging from 1 pg/mL 100 ng/mL, limit detection low 0.48 pg/mL. Moreover, as-prepared sensing strategy shows accurate fluid samples.

Language: Английский

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Simple and direct electrochemical detection of rosmarinic acid in food samples based on nanochannel modified carbon electrode

RSC Advances, Journal Year: 2024, Volume and Issue: 14(26), P. 18599 - 18607

Published: Jan. 1, 2024

A simple electrochemical sensor was developed by integrating a vertically-ordered mesoporous silica film (VMSF) with pre-activated glassy carbon electrode (p-GCE) to provide dual signal amplification for sensitive detection of rosmarinic acid.

Language: Английский

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Graphitic carbon nitride nanosheet supported silica nanochannel film for enhanced electrochemiluminescence sensing of 2,4,6-trichlorophenol and prochloraz

RSC Advances, Journal Year: 2024, Volume and Issue: 14(39), P. 28976 - 28983

Published: Jan. 1, 2024

Graphitic carbon nitride nanosheet supported silica nanochannel film is easily fabricated for enhanced electrochemiluminescence sensing of 2,4,6-trichlorophenol and prochloraz.

Language: Английский

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Enhanced Electrochemiluminescence of Luminol and-Dissolved Oxygen by Nanochannel-Confined Au Nanomaterials for Sensitive Immunoassay of Carcinoembryonic Antigen

Molecules, Journal Year: 2024, Volume and Issue: 29(20), P. 4880 - 4880

Published: Oct. 15, 2024

Simple development of an electrochemiluminescence (ECL) immunosensor for convenient detection tumor biomarker is great significance early cancer diagnosis, treatment evaluation, and improving patient survival rates quality life. In this work, demonstrated based on enhanced ECL signal boosted by nanochannel-confined Au nanomaterial, which enables sensitive the biomarker-carcinoembryonic antigen (CEA). Vertically-ordered mesoporous silica film (VMSF) with a nanochannel array amine groups was rapidly grown simple low-cost indium tin oxide (ITO) electrode using electrochemically assisted self-assembly (EASA) method. nanomaterials were confined in situ VMSF through electrodeposition, catalyzed both conversion dissolved oxygen (O

Language: Английский

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Nanochannel confined graphene quantum dots/platinum nanoparticles boosts electrochemiluminescence of luminal-O2 system for sensitive immunoassay

Talanta, Journal Year: 2024, Volume and Issue: 285, P. 127223 - 127223

Published: Nov. 20, 2024

Language: Английский

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Solid-phase electrochemiluminescence immunosensing platform based on bipolar nanochannel array film for sensitive detection of carbohydrate antigen 125

Frontiers in Chemistry, Journal Year: 2024, Volume and Issue: 12

Published: Oct. 25, 2024

Development of simple solid-phase electrochemiluminescence (ECL) immunosensor with convenient fabrication for high-performance detection tumor biomarkers is crucial. Herein, a ECL immunoassay was constructed based on bipolar silica nanochannel film (bp-SNA) modified electrode highly sensitive carbohydrate antigen 125 (CA 125). Inexpensive and readily available indium tin oxide (ITO) used as the supporting growth bp-SNA. bp-SNA consists bilayer SNA different functional groups charge properties, including negatively charged inner layer (n-SNA) positively outer (p-SNA). The nanochannels were immobilization emitter tris(bipyridine)ruthenium(II), while surface utilized constructing immunorecognition interface. Due to dual electrostatic interaction composed attraction from n-SNA repulsion p-SNA, could be stably confined within bp-SNA, providing stable high signals electrode. After amino derivatized aldehyde groups, recognition antibodies covalently immobilized, an obtained after blocking nonspecific sites. When CA binds interface, formed complex reduces diffusion co-reactant tripropylamine (TPrA) electrode, decreasing signal. Based this mechanism, can achieve 125. linear range 0.01 100 U/mL, limit 4.7 mU/mL. in serum also achieved. construction has advantages fabrication, stability immobilized emitter, selectivity, making it suitable detection.

Language: Английский

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Solid-Phase Electrochemiluminescence Immunosensing Platform Based on Bipolar Nanochannel Array Film for Sensitive Detection of Cancer Antigen 125

Published: Jan. 1, 2024

Language: Английский

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Sensitive detection of gallic acid in food by electrochemical sensor fabricated by integrating nanochannel film with nanocarbon nanocomposite

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Nov. 12, 2024

Sensitive detection of gallic acid (GA) in foods is great significance for assessing the antioxidant properties products and ensuring consumer health. In this work, a simple electrochemical sensor was conveniently fabricated by integrating vertically-ordered mesoporous silica film (VMSF) with electrochemically reduced graphene oxide (ErGO) nitrogen quantum dots (NGQDs) nanocomposite, enabling sensitive GA food sample. A water-soluble mixture (GO) NGQDs drop-cast onto common carbon electrode, glassy electrode (GCE), followed rapid growth VMSF using an assisted self-assembly method (EASA). The negative voltage applied during facilitated situ reduction GO to ErGO. synergistic effects ErGO, NGQDs, nanochannels led nearly tenfold enhancement signal compared that obtained on electrodes modified either ErGO or alone. realized linear concentration range from 0.1 10 μM, 100 μM. limit (LOD), determined based signal-to-noise ratio three ( S / N = 3), found be 81 nM. Combined size-exclusion property VMSF, demonstrated high selectivity, making it suitable samples.

Language: Английский

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Triple-shielded electrochemiluminescent aptasensor based on mesoporous silica film for the highly sensitive detection of aflatoxin B1 in wheat

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: unknown, P. 137137 - 137137

Published: Dec. 1, 2024

Language: Английский

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