Eco-Friendly high Drug-Loading microemulsions with Incorporation of Deep eutectic Solvents: Advancing precision with the dual Ouzo effect

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: 672, P. 125265 - 125265

Published: Feb. 4, 2025

Language: Английский

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Curcumin Electroanalysis at a Disposable Graphite Electrode

Biosensors, Journal Year: 2025, Volume and Issue: 15(3), P. 137 - 137

Published: Feb. 23, 2025

Curcumin (CU, turmeric), a polyphenolic phytochemical that is largely used as food spice, has benefits for human health, which have led to increased interest in its therapeutic applications and analysis from different matrices. The two guaiacol moieties of CU are responsible antioxidant properties allow voltammetric quantification. Cyclic differential pulse voltammetry (DPV) investigations at single-use pencil graphite electrode (PGE) emphasized complex pH-dependent processes, involving an equal number protons electrons. Theoretical calculations predicted folded geometry the β-diketone conformers, interact with PGE surface, exposing electroactive only one aromatic ring. Gibbs energy variations structures involved electro-oxidation theoretical electrochemical potential values were calculated. CU’s DPV cathodic peak intensity recorded HB-type 0.05 mol × L−1 H2SO4 varied linearly range 5.00 10−8–5.00 10−6 CU. method’s detection quantification limits 2.12 10−8 6.42 L−1, respectively. practical applicability developed method, successfully tested by assessment dietary supplements, provided recovery 99.28 ± 2.04%.

Language: Английский

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Green Liquid-Phase Microextraction Using Nonanoic Acid as a Novel Extractant for the Spectrophotometric Determination of Rhodamine B in Cosmetics

Analytical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12

Published: July 24, 2024

A new method for separating and concentrating Rhodamine B (RhB) in cosmetics has been developed using nonanoic acid liquid-phase microextraction (NA-LPmE) with spectrophotometric determination. Nonanoic is a novel environmentally friendly extractant that was used as single component the isolation. In contrast, supramolecular solvents deep eutectic are often combined mixture. The simple, quick, accurate, friendly. appropriate parameters (the volume of NA, pH, sample volume, matrix effects) were optimized these conditions resulted suitable linear range (20.5–1000 µg L−1), low detection limit (6.2 high pre-concentration factor (40). NA-LPmE successfully extracted determined RhB several employs small green solvent determination rapid analysis. combination first time.

Language: Английский

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Recent advances in green solvents-based liquid-phase microextraction techniques for chromatographic analysis of active components in traditional Chinese medicine

Journal of Chromatography A, Journal Year: 2024, Volume and Issue: 1741, P. 465604 - 465604

Published: Dec. 17, 2024

Language: Английский

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