A design of Tetrastigma hemsleyanum's flavonoid loaded polyvinylpyrrolidone nanoparticles for improving its bioavailability and biological activities

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 143099 - 143099

Published: Jan. 1, 2025

Language: Английский

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High-Resolution LC-MS Simultaneous Quantification of Forty-Six Compounds from Jatropha podagrica Fruit Recommends Four Top Antioxidant Contributors as Q-Markers

Molecules, Journal Year: 2025, Volume and Issue: 30(3), P. 722 - 722

Published: Feb. 5, 2025

There has been no chemical analysis of the fruit medicinal plant Jatropha podagrica until now. The current study aimed to qualitatively and quantitatively analyze J. using a high-resolution LC-MS strategy, i.e., library-comparison ultra-high-performance liquid chromatography-Quadrupole-Orbitrap-tandem mass spectrometry. strategy putatively identified 46 compounds from fresh fruit. During putative identification, 10 isomers (e.g., (vitexin vs. isovitexin) were completely distinguished each other. Thereafter, all simultaneously quantified authentic standard comparison method. Finally, they also subjected 2,2′-azino bis (3-ethylbenzothiazolin-6-sulfonic acid radical (ABTS+•)-scavenging assay characterize their relative antioxidant capacities. Their capacities thus multiplied by contents calculate contribution values, respectively. Corilagin, gallic acid, ellagic phillygenin exhibited highest percentages thereby suggested as four top contributors. are recommended build up quality-markers (Q-markers) system fruits. All these findings can help develop fruits potential resource natural medicine.

Language: Английский

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Identification of Tannin from Phyllanthus emblica and Its Mechanism of Astringency Caused by Interaction with Saliva Protein In Vitro

Food and Bioprocess Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

Language: Английский

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Simultaneous Quantification of 66 Compounds in Two Tibetan Codonopsis Species Reveals Four Chemical Features by Database-Enabled UHPLC-Q-Orbitrap-MS/MS Analysis

Molecules, Journal Year: 2024, Volume and Issue: 29(21), P. 5203 - 5203

Published: Nov. 3, 2024

Codonopsis canescens Nannf. (CoC) and nervosa (CoN) are two traditional Tibetan medicinal herbs (Zangdangshen), which have been widely used in the treatment of various diseases. In this study, their aerial underground parts were systematically analyzed using database-enabled UHPLC-Q-Orbitrap-MS/MS technology. This technology introduced three adduct ions, [M − H]−, + H]+, NH4]+, to putatively identify a total 66 compounds. During putative identification, at least 16 isomers successfully differentiated, such as isochlorogenic acid A vs. B C. Thereafter, all these identified compounds further quantified for contents based on linear regression method. Their observed vary from 0.00 39,127.03 µg/g. Through multiple comparisons quantification results, study found following four chemical features: (1) Four sesquiterpenes (especially atractylenolide III) enriched mainly CoC rarely CoN; (2) quinic derivatives abundant part species; (3) sixteen flavonoids (particularly diosmetin chrysoeriol) showed higher content than (4) lobetyolin was ubiquitously distributed both CoN. Based features relevant principles, (lobetyolin, III, diosmetin, recommended quality markers species. All findings can facilitate sustainable development control herbs.

Language: Английский

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Comparative study on the spatiotemporal variation of four chemical components in different Eucommia ulmoides cultivars

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112583 - 112583

Published: Dec. 1, 2024

Language: Английский

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