Antibiotics, Journal Year: 2024, Volume and Issue: 13(11), P. 1038 - 1038

Published: Nov. 3, 2024

With ever-developing analytical capabilities, the protection of dairy chain from contamination by residues veterinary drugs is improving. Legislative requirements are an inherent part this process. Of antibiotics in farming, representatives beta-lactams, tetracyclines, sulfonamides, (fluoro)quinolones, aminoglycosides, or polypeptide most widely used. Due to typically low levels antibiotic milk, mass spectrometry commonly used detection technique. However, interference sample matrix one its main limiting factors, and therefore, it needs be eliminated. In first step, lipid fraction removed proteins precipitated, followed solid-phase liquid–liquid extraction. The current trends include reduction consumption organic solvents (to reduce occupational hazards burden environment) automation, eliminating influence human error optimizing workflow. These lead development new microextraction automated techniques as well use sorbents and/or (green) natural origin. To capture latest developments field relatively recent aforementioned trends, review focuses on papers investigating antimicrobial milk that were published between 2015 2024, providing overview emerging applicable residue samples.

Language: Английский