Nanozymes-Mediated Lateral Flow Assays for the Detection of Pathogenic Microorganisms and Toxins: A Review from Synthesis to Application DOI
Sofiène Mansouri

Critical Reviews in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 20

Published: April 18, 2025

In today's context, there is an increasing awareness among individuals regarding the importance of healthy and safe food consumption. Consequently, a growing demand for products that are safeguarded against detrimental effects pathogens harmful microbial metabolites. Actually, these organisms their associated toxins pose significant risk to safety recognized as critical threat human health because capacity induce foodborne infections intoxications. in order address such challenges, it imperative enhance recognizing systems comprising bio/nanosensors detections, which trustworthy, quick, beneficial economical. The advent digital color imaging technology has led gradual establishment lateral flow assays (LFAs) one most sensors point-of-care applications. Unlike colloidal gold nanoparticles (AuNPs), nanozymes offer enhanced intensity through target-induced precise enrichment at test line. Additionally, they amplify signal by facilitating catalytic oxidation colorless substrates into colored products. This dual functionality presents potential development well-organized LFAs. light this, attempts dedicated nanozyme-based review aims outline recent advancements synthesis design with varying compositions exhibit distinct activities, well structure employment LFAs detection pathogenic microorganisms toxins. Furthermore, existing challenges prospective directions outlined assist readers advancing performance.

Language: Английский

Nanozymes-Mediated Lateral Flow Assays for the Detection of Pathogenic Microorganisms and Toxins: A Review from Synthesis to Application DOI
Sofiène Mansouri

Critical Reviews in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 20

Published: April 18, 2025

In today's context, there is an increasing awareness among individuals regarding the importance of healthy and safe food consumption. Consequently, a growing demand for products that are safeguarded against detrimental effects pathogens harmful microbial metabolites. Actually, these organisms their associated toxins pose significant risk to safety recognized as critical threat human health because capacity induce foodborne infections intoxications. in order address such challenges, it imperative enhance recognizing systems comprising bio/nanosensors detections, which trustworthy, quick, beneficial economical. The advent digital color imaging technology has led gradual establishment lateral flow assays (LFAs) one most sensors point-of-care applications. Unlike colloidal gold nanoparticles (AuNPs), nanozymes offer enhanced intensity through target-induced precise enrichment at test line. Additionally, they amplify signal by facilitating catalytic oxidation colorless substrates into colored products. This dual functionality presents potential development well-organized LFAs. light this, attempts dedicated nanozyme-based review aims outline recent advancements synthesis design with varying compositions exhibit distinct activities, well structure employment LFAs detection pathogenic microorganisms toxins. Furthermore, existing challenges prospective directions outlined assist readers advancing performance.

Language: Английский

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