Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown
Published: March 3, 2025
Language: Английский
Citations
1Cerebrolysin in post-TBI recovery: Pharmacology and clinical evidence
Gene Reports, Journal Year: 2025, Volume and Issue: unknown, P. 102202 - 102202
Published: March 1, 2025
Language: Английский
Citations
1The role of Mitofusin-1 and Mitofusin-2 in periodontal disease: a comprehensive review
Frontiers in Oral Health, Journal Year: 2025, Volume and Issue: 6
Published: Jan. 17, 2025
Periodontal disease is a widespread chronic inflammatory state influencing the supporting anatomy of teeth, distinguished by oxidative stress, progressive bone loss, and tissue damage. Recent articles have highlighted significance mitochondrial dynamics, mainly Mitofusin-1 (MFN1) along with Mitofusin-2 (MFN2), inflammation regulation, homeostasis, in cellular function. The aim current study to comprehensively review including evaluate roles MFN2 MFN1 pathogenesis as well progression periodontal disease, foregrounding their effect on integrity, pathways, stress. Studies were selected depending inclusion criteria based health. Data from chosen vivo, clinical studies, vitro synthesized. Outcomes indicate that are important for preserving function, mitigating damage, fusion. Decreased levels these proteins related elevated inflammation, increased dysfunction tissues. comprehensive shows cell survival, dynamics within disease. prospective targeting therapeutic policy promising, presenting avenues upgraded management regeneration.
Language: Английский
Citations
0Mapping brain neural networks in stress brain connectivity
Progress in brain research, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0Impact of positive feelings and negative feelings on brain cell regeneration and degeneration
Progress in brain research, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0Mitochondrial-based therapies for neurodegenerative diseases: a review of the current literature
Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown
Published: March 31, 2025
Abstract Neurodegenerative disorders present significant challenges to modern medicine because of their complex etiology, pathogenesis, and progressive nature, which complicate practical treatment approaches. Mitochondrial dysfunction is an important contributor the pathophysiology various neurodegenerative illnesses, including Alzheimer’s disease (AD), Parkinson’s (PD), amyotrophic lateral sclerosis (ALS). This review paper examines current literature highlighting multifaceted functions mitochondria, energy production, calcium signaling, apoptosis regulation, mitochondrial biogenesis, dynamics, axonal transport, endoplasmic reticulum–mitochondrial interactions, mitophagy, proteostasis, crucial involvement in neuronal health. The emphasizes increasing recognition as a critical factor progression disorders, marking shift from traditional symptom management innovative mitochondrial-based therapies. By discussing mechanisms, quality control (MQC) processes impact oxidative stress, this highlights need for novel therapeutic strategies restore function, protect connections integrity, slow progression. comprehensive aims provide insights into potential interventions that could transform landscape diseases, addressing symptoms underlying pathophysiological changes.
Language: Английский
Citations
0Mitochondrial Dynamics Regulators in Cancer Metabolism and Progression
Mitochondrial Communications, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0Various zebrafish models of Parkinson's disease: What gives us hope
Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 219 - 230
Published: Nov. 29, 2024
Language: Английский
Citations
1Unveiling Stroke: Biomarkers and Diagnostic Strategies
Published: Jan. 1, 2024
Citations
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