Bacillus proteolyticus UPMC1508: A novel bacterial strain capable of biologically synthesize iron oxide nanoparticles DOI

Yusur Ramzi Hasan,

Fadzlie Wong Faizal Wong, Murni Halim

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 5, 2024

Abstract Antibiotic resistance is a growing concern due to the overuse of antibiotics. Alternative treatments, such as nanoparticles, are being explored. Biological synthesis iron oxide nanoparticles (Fe3O4-NPs) via probiotics offers sustainable and cost-effective method over toxic chemical approaches, but there challenges regarding its heavy metal toxicity obtained nanoparticles. Thus, this research aims biologically synthesize Fe₃O₄-NPs new bacterial isolate evaluate toxicity. The objectives characterize novel with probiotic potential. Then, Fe3O4-NPs Transmission Electron Microscopy (TEM), Field Emission Scanning (FE-SEM), Powder Diffraction Techniques (XRD), Fourier Transform Infrared Spectroscopy (FT-IR), nanosizer. Finally, cytotoxicity potential MTT– (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays. A total 12 samples were collected from six different sites in Selangor, Malaysia. 16s rRNA sequencing came closest Bacillus proteolyticus UPMC1508 (99.87%). This strain has lower antibiotic high Fe-tolerance (MTC = 0.8 mg.mL− 1). It successfully synthesized Fe3O4-NPs, which exhibited absorption curves between 290–300 nm. TEM FE-SEM indicated spherical formed Fe3O4-NPs; average diameter was 5.12 ± 0.95 Meanwhile, XRD peaks revealed that grain size around 32.61 nanosizer hydrodynamic 104 nm good Polydispersity index (PDI) value (0.217). FT-IR satisfactory stability after 2 months. showed low at 0.031 1.The findings isolated B. Fe-heavy tolerance less resistance. Furthermore, it safety, making them suitable for therapeutic platforms, antibacterial anticancer. significance study lies offering an eco-friendly, low-cost approach while expanding applicability safe biomedical applications.

Language: Английский

Ferric citrate enhanced bioreduction of Cr(VI) by Bacillus cereus RCr in aqueous solutions: reduction performance and mechanisms DOI

Yishuo Wang,

Fei Huang, Jiaxin Liu

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(36), P. 48972 - 48985

Published: July 23, 2024

Language: Английский

Citations

0
Five‐ or six‐membered aluminum metallocyclic complexes containing N, N bidentate oxazolinyl‐indolate chelate ring: Synthesis, structural, and catalytic studies DOI

H. L. Chung,

Cian‐Fu Li,

Ming‐Tsz Chen

et al.

Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 38(11)

Published: Aug. 5, 2024

Treatment of two classes oxazolinyl‐indolate ligand precursors with an equivalent trimethylaluminum reagent afforded four corresponding aluminum dimethyl complexes. Intramolecular functional groups were employed to switch coordination behaviors, resulting in the formation five‐ or six‐membered metallocyclic The screening prepared complexes, mediated by 9‐anthracenemethanol as initiating ring‐opening polymerization ε‐caprolactone, showed significant activities at room temperature. compound ligated 2‐(1 H ‐indol‐2‐yl)‐4,4‐dimethyl‐4,5‐dihydrooxazole possessed a suitable chelated ring size, and its intrinsic electronic properties maintained higher activity.

Language: Английский

Citations

0
Bacillus proteolyticus UPMC1508: A novel bacterial strain capable of biologically synthesize iron oxide nanoparticles DOI

Yusur Ramzi Hasan,

Fadzlie Wong Faizal Wong, Murni Halim

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 5, 2024

Abstract Antibiotic resistance is a growing concern due to the overuse of antibiotics. Alternative treatments, such as nanoparticles, are being explored. Biological synthesis iron oxide nanoparticles (Fe3O4-NPs) via probiotics offers sustainable and cost-effective method over toxic chemical approaches, but there challenges regarding its heavy metal toxicity obtained nanoparticles. Thus, this research aims biologically synthesize Fe₃O₄-NPs new bacterial isolate evaluate toxicity. The objectives characterize novel with probiotic potential. Then, Fe3O4-NPs Transmission Electron Microscopy (TEM), Field Emission Scanning (FE-SEM), Powder Diffraction Techniques (XRD), Fourier Transform Infrared Spectroscopy (FT-IR), nanosizer. Finally, cytotoxicity potential MTT– (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays. A total 12 samples were collected from six different sites in Selangor, Malaysia. 16s rRNA sequencing came closest Bacillus proteolyticus UPMC1508 (99.87%). This strain has lower antibiotic high Fe-tolerance (MTC = 0.8 mg.mL− 1). It successfully synthesized Fe3O4-NPs, which exhibited absorption curves between 290–300 nm. TEM FE-SEM indicated spherical formed Fe3O4-NPs; average diameter was 5.12 ± 0.95 Meanwhile, XRD peaks revealed that grain size around 32.61 nanosizer hydrodynamic 104 nm good Polydispersity index (PDI) value (0.217). FT-IR satisfactory stability after 2 months. showed low at 0.031 1.The findings isolated B. Fe-heavy tolerance less resistance. Furthermore, it safety, making them suitable for therapeutic platforms, antibacterial anticancer. significance study lies offering an eco-friendly, low-cost approach while expanding applicability safe biomedical applications.

Language: Английский

Citations

0