Magnetic mesoporous silica nanoparticles as advanced polymeric scaffolds for efficient cancer chemotherapy: recent progress and challenges DOI Creative Commons
Sara Payamifar,

Yasaman Khalili,

Amin Foroozandeh

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(20), P. 16050 - 16074

Published: Jan. 1, 2025

Magnetic mesoporous silica nanoparticles stand out as excellent options for targeted chemotherapy owing to their remarkable features.

Language: Английский

Current Trends in Silica Based Drug Delivery Systems DOI Creative Commons

Rozhan Khoz,

Fateme Yazdian,

Mehrab Pourmadadi

et al.

European Journal of Medicinal Chemistry Reports, Journal Year: 2024, Volume and Issue: 12, P. 100206 - 100206

Published: Aug. 23, 2024

Language: Английский

Citations

6
Carboxylated celluloses as effective stabilizers for super-stable Pickering emulsions: Effects of different carboxyl moieties and particle morphologies on performance DOI
Xiaoyun Chen, Feifan Zhang,

Qiaomei Yang

et al.

Food Hydrocolloids, Journal Year: 2024, Volume and Issue: 160, P. 110735 - 110735

Published: Oct. 11, 2024

Language: Английский

Citations

6
Carboxymethyl Starch: A Contemporary Paradigm for Anti Cancer Drug Delivery DOI Open Access
Rabab Fatima

Drug Development Research, Journal Year: 2025, Volume and Issue: 86(2)

Published: March 27, 2025

ABSTRACT Carboxymethyl starch (CMS) represents a significant advancement in addressing the multifaceted challenges of anticancer drug delivery, including poor aqueous solubility, nonspecific biodistribution, and premature release. The strategic incorporation carboxymethyl moiety (‐CH 2 COOH) onto backbone confers suite physicochemical properties that markedly enhance its efficacy as carrier. groups, with pKa approximately 4.5, exhibit pronounced pH‐responsiveness, undergoing transition from predominantly deprotonated, hydrophilic state at physiological pH (7.4) to more protonated form acidic tumor microenvironment (pH 6.5–6.8) facilitating targeted release neoplastic site. mucoadhesive attributes ascribable carboxyl‐mucin interactions, prolong gastrointestinal residence time for oral formulations, optimizing absorption. Furthermore, these functional groups serve reactive sites subsequent modifications, development multifunctional, delivery systems enhanced biocompatibility minimized off‐target effects. versatility CMS position it promising platform next‐generation therapeutics, offering potential advancements oncological treatment modalities.

Language: Английский

Citations

0
A synergistic nanocomposite of tragacanth gum, starch, and graphitic carbon nitride: a cutting-edge platform for lornoxicam delivery DOI

Aamir Nawaz,

Muhammad Babar Taj, Μαρία Αντωνιάδου

et al.

New Journal of Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Biomaterials are getting more recognition in drug delivery due to their unique intrinsic properties.

Language: Английский

Citations

0
Novel pH-Responsive Folic Acid-Conjugated Zein-Carboxymethyl Cellulose Nanoparticles for Enhanced and Controlled Curcumin Release DOI Creative Commons
Merve Öztekin, Yeşim Sağ

Journal of Pharmaceutical Innovation, Journal Year: 2025, Volume and Issue: 20(3)

Published: May 6, 2025

Language: Английский

Citations

0
Investigation of fast in situ injectable carboxymethylcellulose-xanthan gum hydrogel via acyl hydrazone linkages for tissue regeneration DOI
My-An Tran Le,

Lam Thanh Duong-Huu,

Tin Dai Luong

et al.

Cellulose, Journal Year: 2025, Volume and Issue: unknown

Published: May 8, 2025

Language: Английский

Citations

0
Magnetic mesoporous silica nanoparticles as advanced polymeric scaffolds for efficient cancer chemotherapy: recent progress and challenges DOI Creative Commons
Sara Payamifar,

Yasaman Khalili,

Amin Foroozandeh

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(20), P. 16050 - 16074

Published: Jan. 1, 2025

Magnetic mesoporous silica nanoparticles stand out as excellent options for targeted chemotherapy owing to their remarkable features.

Language: Английский

Citations

0