Value of the modified Patient‐Generated Subjective Global Assessment in indicating the need for nutrition intervention and predicting overall survival in patients with malignant tumors in at least two organs

Nutrition in Clinical Practice, Journal Year: 2024, Volume and Issue: 39(4), P. 920 - 933

Published: March 9, 2024

Abstract Background Although the Patient‐Generated Subjective Global Assessment (PG‐SGA) is a reference standard used to assess patient's nutrition status, it cumbersome administer. The aim of present study was estimate value simpler and easier‐to‐use modified PG‐SGA (mPG‐SGA) evaluate status need for intervention in patients with malignant tumors at least two organs. Methods A total 591 (343 male 248 female) were included from INSCOC study. Pearson correlation analysis conducted between mPG‐SGA nutrition‐related factors, optimal cut‐off defined by receiver operating characteristic curve (ROC). consistency compared concordance analysis. survival determine effects nutritional among different groups. Univariable multivariable Cox analyses applied association all‐cause mortality. Results showed negative factors. Individuals an ≥ 5 (rounded 4.5) considered intervention. Among malnourished (mPG‐SGA 5), overall (OS) those who received significantly higher than that did not. However, OS not better‐nourished < 5). Conclusion Our findings support feasible tool can be guide interventions predict affecting

Language: Английский

---

Naples Prognostic Score: A Novel Predictor of Survival in Patients with Triple-Negative Breast Cancer

Journal of Inflammation Research, Journal Year: 2024, Volume and Issue: Volume 17, P. 5253 - 5269

Published: Aug. 1, 2024

This study investigated the correlation between Naples prognostic score (NPS), clinicopathological traits, and postoperative prognoses of patients with triple-negative breast cancer (TNBC). Based on NPS, a predictive nomogram was developed to estimate long-term survival probabilities TNBC post-surgery.

Language: Английский

---

A Holistic Approach to Hard-to-Treat Cancers: The Future of Immunotherapy for Glioblastoma, Triple Negative Breast Cancer, and Advanced Prostate Cancer

Biomedicines, Journal Year: 2023, Volume and Issue: 11(8), P. 2100 - 2100

Published: July 25, 2023

Immunotherapy represents an attractive avenue for cancer therapy due to its tumour specificity and relatively low frequency of adverse effects compared other treatment modalities. Despite many advances being made in the field immunotherapy, very few immunotherapeutic treatments have been approved difficult-to-treat solid tumours such as triple negative breast (TNBC), glioblastoma multiforme (GBM), advanced prostate (PCa). The anatomical location some these cancers may also make them more difficult treat. Many trials focus solely on immunotherapy failed consider or manipulate, prior intervention, important factors microbiota, which itself is directly linked lifestyle factors, diet, stress, social support, exercise, sleep, oral hygiene. This review summarises most recent hard-to-treat whilst factoring less conventional interventions could tilt balance favour success malignancies.

Language: Английский

---

Take the bull by the horns and tackle the potential downsides of the ketogenic diet

Nutrition, Journal Year: 2024, Volume and Issue: 125, P. 112480 - 112480

Published: May 2, 2024

Language: Английский

---

Microencapsule delivery systems of functional substances for precision nutrition

Advances in food and nutrition research, Journal Year: 2024, Volume and Issue: unknown, P. 199 - 255

Published: Jan. 1, 2024

Language: Английский

---