Synthesis and Structure Characterization of Three Pharmaceutical Compounds Based on Tinidazole DOI Creative Commons
Na Li, Yu‐Ting Chen, Ruixin Chen

et al.

Crystals, Journal Year: 2023, Volume and Issue: 13(6), P. 947 - 947

Published: June 12, 2023

Tinidazole (TNZ), a 5-nitroimidazole derivative, has received increasing attention due to its pharmacological activities in treatment for amebic and parasitic infections. In this paper, we synthesized three novel drug supramolecular compounds successfully based on TNZ. The discussed were formed by TNZ 2,6-dihydroxybenzoic acid (2,6-DHBA), 4-methylsalicylic (4-MAC), 5-chloro-2-hydroxybenzoic (5-C-2-HBA). N-H···O O-H···O hydrogen bonds weak C-H···O are the primary intermolecular forces construction of compounds. Crystal structure analysis revealed that all exhibit three-dimensional frameworks consisting non-covalent interactions. Furthermore, six synthons, Ⅰ R22 (8), Ⅱ R21(6), Ⅲ R22(12), Ⅳ R33(9), Ⅴ Ⅵ through various found Moreover, resulting pharmaceutical show improved stability. Single-crystal X-ray diffraction analysis, infrared spectroscopy (IR), element thermogravimetric (TGA) reported.

Language: Английский

Two novel quinoline-decorated half-salamo-type Co(II) complexes: Synthesis, crystal structure, Hirshfeld surface analysis, DFT calculation and fluorescence properties DOI
Li Tong, Li-Li Man, Xun Li

et al.

Journal of Molecular Structure, Journal Year: 2023, Volume and Issue: 1294, P. 136372 - 136372

Published: Aug. 9, 2023

Language: Английский

Citations

25
Supramolecular networks featuring diverse array of noncovalent interactions in crystals of hydrazinylidene-benzothiazinediones: X-ray crystallographic, DFT and biochemical analysis DOI
Sumera Zaib, Rubina Munir, Imtiaz Khan

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1306, P. 137840 - 137840

Published: Feb. 21, 2024

Language: Английский

Citations

4
An ultrastable cationic covalent organic framework for selective capture of silver from aqueous solution DOI
Jikuan Qiu, Chang Xu,

Xianhui Xu

et al.

Journal of Molecular Structure, Journal Year: 2023, Volume and Issue: 1292, P. 136173 - 136173

Published: July 7, 2023

Language: Английский

Citations

9
N,N-Dimethylbenzylamine as a Coformer for 3 Crystalline Organic Salts: Preparation, Spectral, Structural Investigation, Synthons Diversity and Hirshfeld Surface Analysis DOI
Rui Gao, Shouwen Jin, Zhaozhi Li

et al.

Journal of Chemical Crystallography, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Language: Английский

Citations

0
Eight anhydrous organic salt forms of 2-amino-4,6-dimethoxypyrimidine and organic acids: Preparation, structure, characterizations, synthons diversity, and hirshfeld surface analysis DOI

Xingjun Gao,

Yangling Ji,

Xusen Gong

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1310, P. 138207 - 138207

Published: April 4, 2024

Language: Английский

Citations

3
Intermolecular interaction of azide, cyano and alkyne-N-phenethylacetamide dimers: Experimental and quantum chemical approach DOI
Alberto Cedillo–Cruz,

Diana Cecilia Villalobos–López,

Nieves Zavala‐Segovia

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1309, P. 138178 - 138178

Published: March 28, 2024

Language: Английский

Citations

1
Crystal and Molecular Structures of Three Co-crystals from 1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione and Carboxylic Acids DOI
Zhaozhi Li, Xianhong Wen, Shouwen Jin

et al.

Journal of Chemical Crystallography, Journal Year: 2023, Volume and Issue: 54(1), P. 41 - 53

Published: Dec. 2, 2023

Language: Английский

Citations

1
Preparation, crystallographic feature, synthon investigation and Hirshfeld surface analysis of both 3D supramolecular anhydrous organic salts constructed by triphenylmethylamine, 3-nitrophthalic acid and 5-nitroisophthalic acid DOI
Zhaozhi Li,

Xiaodan Ma,

Shiyi Chen

et al.

Structural Chemistry, Journal Year: 2024, Volume and Issue: 36(1), P. 101 - 111

Published: June 14, 2024

Language: Английский

Citations

0
Synthesis and Structure Characterization of Three Pharmaceutical Compounds Based on Tinidazole DOI Creative Commons
Na Li, Yu‐Ting Chen, Ruixin Chen

et al.

Crystals, Journal Year: 2023, Volume and Issue: 13(6), P. 947 - 947

Published: June 12, 2023

Tinidazole (TNZ), a 5-nitroimidazole derivative, has received increasing attention due to its pharmacological activities in treatment for amebic and parasitic infections. In this paper, we synthesized three novel drug supramolecular compounds successfully based on TNZ. The discussed were formed by TNZ 2,6-dihydroxybenzoic acid (2,6-DHBA), 4-methylsalicylic (4-MAC), 5-chloro-2-hydroxybenzoic (5-C-2-HBA). N-H···O O-H···O hydrogen bonds weak C-H···O are the primary intermolecular forces construction of compounds. Crystal structure analysis revealed that all exhibit three-dimensional frameworks consisting non-covalent interactions. Furthermore, six synthons, Ⅰ R22 (8), Ⅱ R21(6), Ⅲ R22(12), Ⅳ R33(9), Ⅴ Ⅵ through various found Moreover, resulting pharmaceutical show improved stability. Single-crystal X-ray diffraction analysis, infrared spectroscopy (IR), element thermogravimetric (TGA) reported.

Language: Английский

Citations

0