Diastereoselective synthesis of cis‐1,2‐limonene oxide using dimeric Salen‐Mn (III) complexes as reusable catalysts DOI
Jairo Cubillos, Juan Alejandro Rubio Rodríguez, J.J. Murcia

et al.

Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 38(3)

Published: Jan. 26, 2024

Diastereoselective epoxidation of R ‐(+)‐limonene using achiral and racemic dimeric Salen‐Mn (III) complexes as catalysts (( 1a) ( 1b) ) in situ generated dimethyldioxirane (DMDO) an oxidizing agent was explored. The best reaction parameters were: i KHSO 5 / molar ratio = 0.25; ii ‐(+)‐limonene, catalyst 20, iii absence nitrogenous bases (axial ligands), iv ambient temperature (20°C), v catalyst, vi low amount acetone (4 mL). Under these conditions isolated yield to 1,2‐(+)‐limonene oxide diastereomeric excess d.e ), d.y.e major diastereomer cis ‐epoxide) 96%, 77%, 72%, respectively. Moreover, the segregated into a solid phase, while products remained liquid allowing easy separation products. Consequently, could be recycled up three times without appreciable loss its initial catalytic activity.

Language: Английский

Synthesis, crystal structure, and in vitro biological evaluation of bismuth (III) complexes incorporating pyrazinohydrazide‐derived Schiff bases DOI
Chuan‐Hua Li, Ming‐Hui Qiu, Hui‐Min Ma

et al.

Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 38(7)

Published: May 23, 2024

Two new Schiff‐base bismuth (III) complexes were prepared by an equivalent reaction between ligand and Bi (NO 3 ) •5H 2 O with the assistance of Mannitol. The chemical structures two characterized spectroscopic studies (FT‐IR, NMR, MS), elemental analysis, single‐crystal X‐ray diffraction. ligand‐to‐metal ion ratio was found to be 1:1 in complexes. During formation complexes, Schiff bases changed from amidic forms iminol forms, resulting tautomers could coordinate ions produce dinuclear III complexes( 1a 2a ). Structural analyses showed that each held a distorted capped octahedron geometry seven‐coordinate mode Screening vitro biological activities revealed exhibited much higher antimicrobial cytotoxic activity than their parent ligands. complex( close known anticancer drug (Doxorubicin) evaluating against SGC7901 cells, IC 50 value 0.59 μM. effectively induce cell apoptosis its oral acute toxicity for LD50 576 mg kg −1 . content mitochondria nucleus.

Language: Английский

Citations

1
Combination energetic materials consisting of strained rings combined with high heat of formation tetrazoles DOI Open Access
Jake E. Zuckerman,

Montgomery C. St Myer,

Mat­thias Zeller

et al.

ChemPlusChem, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 9, 2024

Abstract The reaction of cyanogen azide with strained‐ring containing primary and secondary amines led to the isolation energetic molecules deriving their energy content from both strained rings as well aminotetrazoles. Azo‐coupling these materials afforded novel high‐nitrogen very high sensitivity. All compounds were chemically characterized by IR, NMR, single‐crystal X‐ray crystallography, high‐resolution mass spectrometry. Their impact friction sensitivities experimentally determined, performances calculated.

Language: Английский

Citations

0
Diastereoselective synthesis of cis‐1,2‐limonene oxide using dimeric Salen‐Mn (III) complexes as reusable catalysts DOI
Jairo Cubillos, Juan Alejandro Rubio Rodríguez, J.J. Murcia

et al.

Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 38(3)

Published: Jan. 26, 2024

Diastereoselective epoxidation of R ‐(+)‐limonene using achiral and racemic dimeric Salen‐Mn (III) complexes as catalysts (( 1a) ( 1b) ) in situ generated dimethyldioxirane (DMDO) an oxidizing agent was explored. The best reaction parameters were: i KHSO 5 / molar ratio = 0.25; ii ‐(+)‐limonene, catalyst 20, iii absence nitrogenous bases (axial ligands), iv ambient temperature (20°C), v catalyst, vi low amount acetone (4 mL). Under these conditions isolated yield to 1,2‐(+)‐limonene oxide diastereomeric excess d.e ), d.y.e major diastereomer cis ‐epoxide) 96%, 77%, 72%, respectively. Moreover, the segregated into a solid phase, while products remained liquid allowing easy separation products. Consequently, could be recycled up three times without appreciable loss its initial catalytic activity.

Language: Английский

Citations

0