An insight into sustainable and green chemistry approaches for the synthesis of quinoline derivatives as anticancer agents

European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 275, P. 116561 - 116561

Published: June 7, 2024

Language: Английский

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Applications of graphene-based photocatalysts for efficient functionalized degradation of some common antibiotics

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 168, P. 112941 - 112941

Published: Aug. 1, 2024

Language: Английский

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Tetrazole derivatives in the management of neurological disorders: Recent advances on synthesis and pharmacological aspects

European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 271, P. 116388 - 116388

Published: April 9, 2024

Language: Английский

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Biogenic synthesis of Pd-Fe@LLR nanocomposites as magnetically recyclable catalysts for C C and C N bond formation

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 161, P. 111927 - 111927

Published: Jan. 4, 2024

Language: Английский

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Recent Updates on Antibacterial Quinolones: Green Synthesis, Mode of Interaction and Structure–Activity Relationship

Chemistry & Biodiversity, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 5, 2025

ABSTRACT Quinolone antibiotics are a crucial class of synthetic antibacterial agents, widely utilized due to their broad spectrum activity. Due the development antimicrobial resistance, potency quinolone drugs decreased. Many conventional methods have been developed elevate amination rate and improve yield. These generally characterized by prolonged reaction durations, high boiling solvents, harsh conditions, costly reagents excessive heat generation, which adversely affected therapeutic efficacy these compounds. Recently, green chemistry has focused on sustainable chemistry‐dependent analogue synthesis that significantly reduce bacterial infections. include one‐pot synthesis, photoredox catalysis, phase transfer ultrasonic irradiation, microwave‐assisted, solvent catalyst‐free often utilize energy‐efficient, non‐toxic less time‐consuming techniques, aligning with principles safety environmental impact. Researchers continuously explore innovative approaches applying in reactions. This review includes comprehensive analysis literature from past 15 years Scopus, PubMed, Embase WOS using keywords, such as chemistry, antibacterial, highlighting significant advancements emerging trends. work's importance lies its extensive overview for quinolones related heterocyclic Furthermore, provide useful information generation future drugs, some structural–activity relationship studies silico also included investigate stable binding interactions between leads various target proteins.

Language: Английский

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Exploring 4-quinolone-3-carboxamide derivatives: A versatile framework for emerging biological applications

Bioorganic Chemistry, Journal Year: 2025, Volume and Issue: 157, P. 108240 - 108240

Published: Feb. 3, 2025

Language: Английский

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Confirmation of enrofloxacin, ofloxacin, sarafloxacin and danofloxacin residues in poultry meat and pork via LLE-SPE-GC–MS/MS coupled with derivatization treatment

Food Chemistry X, Journal Year: 2025, Volume and Issue: unknown, P. 102393 - 102393

Published: March 1, 2025

Language: Английский

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One-pot Synthesis of Condensed Azepines

Current Organic Chemistry, Journal Year: 2024, Volume and Issue: 28(11), P. 815 - 829

Published: May 6, 2024

Abstract: Azepine is a privileged nitrogen-containing ring that has been found to display wide range of biological activities. valuable skeleton in designing novel compounds medicinal chemistry due its interesting chemical and properties. The study on the synthesis this system engenders fascinating area research owing potential form an active pharmacophore for De Novo exploration. In study, conventional domino results were compared access diverse set azepines high yield. approach revolutionized way through which previously impossible yet significant transformations could be conceptualized, allowing construction difficult materials one step. aim present mini-review highlight importance one-pot reaction condensed azepines. This review also presents subject from past two decades.

Language: Английский

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Reagent-Free Intramolecular Hydroamination of Ynone-Tethered Aryl-sulfonamide: Synthesis of Polysubstituted 4-Quinolones

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 30, 2024

An efficient reagent-free method for the synthesis of polysubstituted 4-quinolone from 2-substituted alkynoyl aryl-sulfonamide was developed. This developed tolerates various functional groups and gives corresponding 4-quinolones. We have successfully extended this to dihydro-4-quinolones 2-alkenoyl aryl sulfonamide derivatives.

Language: Английский

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Iodine‐Mediated Oxidative C=C Double‐Bond Formation toward Fused Quinolinones and Quinolinium Salts

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 29, 2024

Abstract An iodine‐mediated C=C double bond‐forming reaction has been established to access various fused quinolinone derivatives under transition metal‐free conditions. The present is also applicable the synthesis of quinolinium frameworks from corresponding precursors and can be conducted on a gram scale.

Language: Английский

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