From Psychoactivity to Antimicrobial Agents: Multifaceted Applications of Synthetic Cathinones and Catha edulis Extracts DOI Creative Commons
Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(24), P. 5918 - 5918

Published: Dec. 15, 2024

The emergence of new psychoactive substances (NPS) in the global drug market since 2000s has posed major challenges for regulators and law enforcement agencies. Among these, synthetic cathinones have gained prominence due to their stimulant effects on central nervous system, leading widespread recreational use. These compounds, often marketed as alternatives illicit stimulants such amphetamines cocaine, been linked numerous cases intoxication, addiction death. structural diversity enantiomeric forms further complicate detection regulation pose forensic toxicology. In addition toxicological effects, research suggests that may antimicrobial properties. Compounds derived from Catha edulis (khat), including cathinone, shown activity against multidrug-resistant bacteria Staphylococcus aureus Escherichia coli, highlighting potential role fight antibiotic resistance. This article provides an overview chemistry, pharmacokinetics, pharmacodynamics, applications cathinones. therapeutic use cathinone-derived compounds combat resistance represents exciting frontier development, although is needed balance these benefits with risks.

Language: Английский

Nano-Crafting Copper Oxide: A novel electrode fabrication for enhanced electrochemical tryptophan detection and efficient photodegradation of Nile Blue dye DOI

Husenappa Vaddar,

Vijayakumar D. Jangannanavar,

Hanumantagouda Basavanagoudra

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

0
Physical and Surface Chemical Analysis of High-Quality Antimicrobial Cotton Fabrics Functionalized with CuOx Gown In Situ from Different Copper Salts: Experimental and Theoretical Approach DOI
Luz Esmeralda Román Mendoza, Carmen Uribe, F. Paraguay‐Delgado

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

The emergence of harmful microorganisms poses a public health challenge. Antimicrobial cotton textiles with semiconductor oxides offer promising solution to mitigate pathogen spread. Here, we study the physicochemical interactions between copper (CuO

Language: Английский

Citations

0
From Psychoactivity to Antimicrobial Agents: Multifaceted Applications of Synthetic Cathinones and Catha edulis Extracts DOI Creative Commons
Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(24), P. 5918 - 5918

Published: Dec. 15, 2024

The emergence of new psychoactive substances (NPS) in the global drug market since 2000s has posed major challenges for regulators and law enforcement agencies. Among these, synthetic cathinones have gained prominence due to their stimulant effects on central nervous system, leading widespread recreational use. These compounds, often marketed as alternatives illicit stimulants such amphetamines cocaine, been linked numerous cases intoxication, addiction death. structural diversity enantiomeric forms further complicate detection regulation pose forensic toxicology. In addition toxicological effects, research suggests that may antimicrobial properties. Compounds derived from Catha edulis (khat), including cathinone, shown activity against multidrug-resistant bacteria Staphylococcus aureus Escherichia coli, highlighting potential role fight antibiotic resistance. This article provides an overview chemistry, pharmacokinetics, pharmacodynamics, applications cathinones. therapeutic use cathinone-derived compounds combat resistance represents exciting frontier development, although is needed balance these benefits with risks.

Language: Английский

Citations

0