Photothermally Active Quantum Dots in Cancer Imaging and Therapeutics: Nanotheranostics Perspective

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 11, 2024

Cancer is becoming a global threat, as the cancerous cells manipulate themselves frequently, resulting in mutants and more abnormalities. Early-stage real-time detection of cancer biomarkers can provide insight into designing cost-effective diagnostic therapeutic modalities. Nanoparticle quantum dot (QD)-based approaches have been recognized clinically relevant methods to detect disease at molecular level. Over decades, an emergent noninvasive approach, photothermal therapy has evolved eradicate cancer. Moreover, various structures, viz., nanoparticles, clusters, dots, etc., tested bioimaging agents identify tumor selectively. Among them, QDs versatile probes. They attracted enormous attention for imaging applications due their unique colloidal stability, optical physicochemical properties, biocompatibility, easy surface conjugation, scalable production, etc. However, few critical concerns QDs, precise engineering sensing, selective interaction with biological system, associated toxicity, restrict potential intervention curing are yet be explored. According U.S. Food Drug Administration (FDA), there no specific regulation approval nanomedicines. Therefore, these nanomedicines undergo traditional drug, biological, device process. market survey increasing, prospects translational nanomedicine very promising. From this perspective, we discuss importance imaging, usage pertinent cancer, especially its early stages. also rapidly growing view QDs. The long-term safety studies cellular could enhance visibility bring photothermally active clinical stage concurrently FDA approval.

Language: Английский

An Approach for Highly Enantioselective Synthesis of meta-Disubstituted [n]Paracyclophanes

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 27, 2024

Atroposelective synthesis of

Language: Английский

Comprehensive evaluation of the nephrotoxicity of carbon quantum dots: Effects of the surface charge

Chemosphere, Journal Year: 2024, Volume and Issue: 367, P. 143604 - 143604

Published: Oct. 22, 2024

Language: Английский