Ultrasound-assisted extraction of Stachys chasmosericea : phytochemical profile, antioxidant potentials via RACI analysis, and enzyme inhibitory activities

Preparative Biochemistry & Biotechnology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: April 1, 2025

Understanding the bioactive potential of plant extracts requires detailed evaluations their chemical composition and bioactivities. This study investigated profiles, antioxidant properties, enzyme inhibitory activities water methanol Stachys chasmosericea Ayasligil & P.H.Davis obtained via ultrasound-assisted extraction. The extract displayed significantly higher total phenolic flavonoid contents compared to extract. Chromatographic analysis revealed verbascoside chlorogenic acid as dominant compounds in extract, whereas contained levels polar like p-coumaric acid. Antioxidant assays demonstrated extract's superior activity. Conversely, excelled metal chelation. RACI values confirmed overall superiority (RACI = 0.65) over −0.65). Enzyme inhibition stronger activity against AChE, BChE, α-amylase, α-glucosidase, tyrosinase showed weaker inhibition. Both for managing oxidative stress enzyme-related disorders but require further vivo validation. highlights S. chasmosericea, particularly its a promising source natural antioxidants inhibitors. Future research should focus on isolating individual bioactives exploring mechanisms action biological systems.

Language: Английский

Chemical composition and biological activities of essential oils from two Opuntia species growing in Tunisia: an in vitro and in silico studies

Journal of Essential Oil Bearing Plants, Journal Year: 2024, Volume and Issue: 27(6), P. 1460 - 1470

Published: Nov. 1, 2024

Language: Английский