Comparative Study of Stability and Activity of Wild-Type and Mutant Human Carbonic Anhydrase II Enzymes Using Molecular Dynamics and Docking Simulations DOI

Maryam Mapar,

Majid Taghdir, Bijan Ranjbar

et al.

Biochemical and Biophysical Research Communications, Journal Year: 2024, Volume and Issue: 734, P. 150720 - 150720

Published: Sept. 20, 2024

Language: Английский

Synthesis of superparamagnetic Fe3O4-PEG400 nanoparticles: Investigation of the interaction with proteins and toxicity on cells DOI
Ali Valizadeh,

Aboulfazl Mirzapoor,

Zahra Hallaji

et al.

Materials Research Bulletin, Journal Year: 2025, Volume and Issue: unknown, P. 113345 - 113345

Published: Feb. 1, 2025

Language: Английский

Citations

2
Innovative Synthesis of Magnetite Nanoparticles and their Interaction with Two Model Proteins: Human Serum Albumin and Lysozyme DOI Open Access
Ali Valizadeh,

Aboulfazl Mirzapoor,

Zahra Hallaji

et al.

Particle & Particle Systems Characterization, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Abstract The synthesis of magnetite nanoparticles (Fe₃O₄ NPs) has gained significant interest due to their broad applications, particularly in biomedicine and environmental purification. In this study, Fe₃O₄ NPs are synthesized using a novel chemical co‐precipitation method, yielding with excellent characteristics such as saturation magnetization 41.42 emu g −1 , coercivity less than 4 Oe, remanence below 0.4 demonstrating superparamagnetic‐like properties. particles achieved an average size 11 nm displayed robust colloidal stability aqueous suspension for ≈30 days. Additionally, chitosan‐coated (Fe₃O₄‐CS) prepared, which maintained similar magnetic properties slightly lower 38.35 the nonmagnetic CS layer. To assess biomedical applicability these NPs, effects on model proteins human serum albumin lysozyme examined. Circular dichroism studies revealed only slight decreases α‐helix content indicating minimal alterations secondary structure. Moreover, fluorescence indicated local changes protein tertiary structures without disruption. This research highlights potential Fe₃O₄‐CS applications drug delivery controlled release systems stability, biocompatibility, unique

Language: Английский

Citations

2
Simple and user-friendly nucleolus imaging with ultra-narrow bandwidth red emission carbon dots DOI

Seyed-Omid Kalji,

Majid Sadeghizadeh,

Khosro Khajeh

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112659 - 112659

Published: Jan. 1, 2025

Language: Английский

Citations

1
Green emitting carbon dots-immunosensor on magnetic nanoparticles for detection of Nanog antigen as a cancer stem cell biomarker DOI
Fatemeh Mehrabi, Morteza Hosseini, Niloufar Sadeghi

et al.

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: unknown, P. 343960 - 343960

Published: March 1, 2025

Language: Английский

Citations

1
Comparative Study of Stability and Activity of Wild-Type and Mutant Human Carbonic Anhydrase II Enzymes Using Molecular Dynamics and Docking Simulations DOI

Maryam Mapar,

Majid Taghdir, Bijan Ranjbar

et al.

Biochemical and Biophysical Research Communications, Journal Year: 2024, Volume and Issue: 734, P. 150720 - 150720

Published: Sept. 20, 2024

Language: Английский

Citations

0