Optimizing the Construction and Activation of 3D-Printed Electrochemical Sensors: An Experimental Design Approach for Simultaneous Electroanalysis of Paracetamol and Caffeine DOI Creative Commons
José Guilherme A. Rodrigues, Tárcila M. N. da Silva, S. Gomes

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: 10(1), P. 1131 - 1143

Published: Jan. 6, 2025

This work presents an optimization of the construction, treatment, and activation 3D-printed electrochemical sensors (E-3D). For this, was used a 23-full factorial design examining three key variables at two levels: electrode height, diameter, printing speed. Moreover, it evaluates various physical, chemical, methods to treat activate E-3D surface. The techniques impedance spectroscopy cyclic voltammetry (CV) shows that sequential treatments lead highest treatment efficiency activation. Raman atomic force microscopy characterize untreated treated sensor surfaces. optimal methodology applied electroanalysis paracetamol (PAR) caffeine (CAF) simultaneously using CV differential pulse anodic stripping (DPASV). DPASV measurements reveal limits detection 0.44 0.58 μmol L–1 in 0.5 mol H2SO4 medium for PAR CAF, respectively, with activated sensor. principal achievement this emphasizing critical role surface enhancing performance developed electrodes, thereby advancing technological applications sensors.

Language: Английский

Optimizing the Construction and Activation of 3D-Printed Electrochemical Sensors: An Experimental Design Approach for Simultaneous Electroanalysis of Paracetamol and Caffeine DOI Creative Commons
José Guilherme A. Rodrigues, Tárcila M. N. da Silva, S. Gomes

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: 10(1), P. 1131 - 1143

Published: Jan. 6, 2025

This work presents an optimization of the construction, treatment, and activation 3D-printed electrochemical sensors (E-3D). For this, was used a 23-full factorial design examining three key variables at two levels: electrode height, diameter, printing speed. Moreover, it evaluates various physical, chemical, methods to treat activate E-3D surface. The techniques impedance spectroscopy cyclic voltammetry (CV) shows that sequential treatments lead highest treatment efficiency activation. Raman atomic force microscopy characterize untreated treated sensor surfaces. optimal methodology applied electroanalysis paracetamol (PAR) caffeine (CAF) simultaneously using CV differential pulse anodic stripping (DPASV). DPASV measurements reveal limits detection 0.44 0.58 μmol L–1 in 0.5 mol H2SO4 medium for PAR CAF, respectively, with activated sensor. principal achievement this emphasizing critical role surface enhancing performance developed electrodes, thereby advancing technological applications sensors.

Language: Английский

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