Cognitive–Motor Coupling in Multiple Sclerosis: Do Chronological Age and Physical Activity Matter?

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 274 - 274

Published: March 5, 2025

Background: People with multiple sclerosis (MS) often demonstrate both cognitive and physical dysfunctions, particularly greater age lower activity levels, there is evidence of a relationship between these outcomes (i.e., cognitive–motor coupling) in MS. To date, little known about coupling when controlling for chronological levels activity. Objectives: We examined people MS while accounting Methods: The sample included 290 the ages 22 77 years. Participants underwent Symbol Digit Modalities Test (SDMT) processing speed California Verbal Learning Memory Test–Second Edition (CVLT-II) verbal learning memory. completed 6-Minute Walk Timed 25-Foot tests walking endurance speed, respectively. wore an accelerometer 7-day period to measure moderate-to-vigorous (MVPA). Results: bivariate correlation analyses indicated that function had moderate-to-strong associations motor (range rs 0.433 0.459). linear regression SDMT (with range β 0.139 0.145) demographic clinical characteristics. further CVLT-II was associated 0.125 0.135) When MVPA were entered into analyses, still individuals (β = 0.119), 0.115 0.124). Conclusions: Cognitive–motor present independent This warrants investigation underlying mechanism potential approaches management co-occurring MS-related dysfunction.

Language: Английский

Walking Performance is Worse in Black than White People with Multiple Sclerosis

Multiple Sclerosis and Related Disorders, Journal Year: 2025, Volume and Issue: 95, P. 106343 - 106343

Published: Feb. 18, 2025

Language: Английский