Green-synthesized nanoparticles and their therapeutic applications: A review DOI Creative Commons
Shilpa Borehalli Mayegowda, Gitartha Sarma, Manjula Nagalapur Gadilingappa

et al.

Green Processing and Synthesis, Journal Year: 2023, Volume and Issue: 12(1)

Published: Jan. 1, 2023

Abstract Antibiotic-resistant microorganisms are a rising issue when it comes to human health. Microbial pathogens that cause harmful infections quickly becoming resistant the antimicrobial action of traditional antibiotics. Nanotechnology, an innovative sector being indispensable part healthcare and research, has in-depth extensive applications. Nano-compounds have been promising agents, anti-cancerous mediators, vehicles for drug delivery, formulations functional foods, identification pathogens, food packaging industry, many more. However, chemical synthesis nanoparticles (NPs) certain drawbacks such as causing toxicity other adverse effects. For more than decade, use NPs conjugated or green-synthesized gained popularity due two-fold metallic mixed with biological sources. In contrast, synthesized using plant microbial extracts, biologically active components, appear be safe alternative approach they environmentally friendly cost-effective. Such techniques referred “green nanotechnology” “clean technology” feasible alternatives methods. Furthermore, natural biomolecules improved bioavailability minimal side effects, smaller in size higher permeability addition reducing stabilizing agents possessing excellent antioxidant activity. serve potential their affinity towards sulphur-rich amino acids, adhere cell walls by means electrostatic attraction, disrupt cytoplasmic membrane along nucleic acid microbes. They possess anticancer activity owing oxidative stress, damage cellular DNA, lipid peroxidation. The thus therapeutic

Language: Английский

Metal Oxides Nanoparticles: General Structural Description, Chemical, Physical, and Biological Synthesis Methods, Role in Pesticides and Heavy Metal Removal through Wastewater Treatment DOI Creative Commons
Zahrah Alhalili

Molecules, Journal Year: 2023, Volume and Issue: 28(7), P. 3086 - 3086

Published: March 30, 2023

Nanotechnology (NT) is now firmly established in both the private home and commercial markets. Due to its unique properties, NT has been fully applied within multiple sectors like pharmacy medicine, as well industries chemical, electrical, food manufacturing, military, besides other economic sectors. With growing demand for environmental resources from an ever-growing world population, application a very advanced new area sector offers several advantages. A novel template synthesis approach being used promising metal oxide nanostructures preparation. Synthesis of template-assisted nanomaterials promotes greener more protocol compared traditional methods such sol-gel hydrothermal synthesis, endows products with desirable properties applications. It provides comprehensive general view current developments areas drinking water treatment, wastewater agriculture, remediation. In field we focus on adsorption heavy metals persistent substances improved photocatalytic decomposition most common pollutants. The treatment section covers enhanced pathogen disinfection removal, point-of-use organic removal applications, including latest advances pesticide removal.

Language: Английский

Citations

100

Green Synthesis of Nanoparticles and Their Energy Storage, Environmental, and Biomedical Applications DOI Creative Commons
Hanaa M. Abuzeid, C. Julien, Likun Zhu

et al.

Crystals, Journal Year: 2023, Volume and Issue: 13(11), P. 1576 - 1576

Published: Nov. 8, 2023

Green synthesis offers a superior alternative to traditional methods for producing metal and oxide nanoparticles. This approach is not only benign safe but also cost-effective, scalable, straightforward, operating under ambient conditions. Notable metals nanoparticles, such as manganese oxides, iron silver, gold, have been produced using various bio-reductants derived from plant extracts. These biological agents expedite the reduction process stabilize serving dual roles reducing capping agents. review presents green of nanoparticles (NPs) obtained biogenic wastes The green-synthesized nanostructured MnO2 are evaluated potential photocatalyst water treatment an electrode material in lithium-ion batteries supercapacitors. green-derived examined promising antioxidant, anti-inflammatory, anti-diabetic Additionally, this discusses precious specifically silver (Ag NPs) gold (Au NPs), highlighting their medical applications areas like antiviral treatments cancer therapy.

Language: Английский

Citations

98

Metal Oxide Nanoparticles: Review of Synthesis, Characterization and Biological Effects DOI Creative Commons
Andreea Mariana Negrescu, Manuela S. Killian, Swathi Naidu Vakamulla Raghu

et al.

Journal of Functional Biomaterials, Journal Year: 2022, Volume and Issue: 13(4), P. 274 - 274

Published: Dec. 5, 2022

In the last few years, progress made in field of nanotechnology has allowed researchers to develop and synthesize nanosized materials with unique physicochemical characteristics, suitable for various biomedical applications. Amongst these nanomaterials, metal oxide nanoparticles (MONPs) have gained increasing interest due their excellent properties, which a great extent differ from bulk counterpart. However, despite such positive advantages, substantial body literature reports on cytotoxic effects, are directly correlated nanoparticles’ therefore, better control over synthetic parameters will not only lead favorable surface characteristics but may also increase biocompatibility consequently lower cytotoxicity. Taking into consideration enormous potential MONPs, present review discuss most recent developments this referring mainly synthesis methods, physical chemical characterization biological including pro-regenerative antitumor potentials as well antibacterial activity. Moreover, section tackle pressing issue toxic effects MONPs tissues/organs cell lines.

Language: Английский

Citations

93

Green Synthesis of Magnesium Oxide Nanoparticles and Nanocomposites for Photocatalytic Antimicrobial, Antibiofilm and Antifungal Applications DOI Open Access
Marzieh Ramezani Farani, Majid Farsadrooh, Iman Zare

et al.

Catalysts, Journal Year: 2023, Volume and Issue: 13(4), P. 642 - 642

Published: March 23, 2023

Magnesium oxide nanoparticles (MgO NPs) have emerged as potential materials for various biomedical applications due to their unique physicochemical properties, including biodegradability, biocompatibility, cationic capacity, high stability and redox properties. MgO NPs become an attractive platform combat microbes may be a promising alternative overcome challenges associated with eliminating microbial biofilms antibiotic resistance. Hence, the increasing use of in biomedicine, new synthetic strategies are necessary. synthesised using green methods non-toxic, eco-friendly wide range biological, medical catalytic applications. This review presents recent advances biosynthesis by diverse bio-templates, such plant, bacterial, fungal algal extracts. Its photocatalytic properties show suitable inhibitory function against pathogenic agents, proliferation, biofilm formation growth. Furthermore, relevant nanocomposites comprehensively discussed regarding mechanisms effect on microbes, strains, well future perspectives.

Language: Английский

Citations

89

Bio-Inspired Nanomaterials for Micro/Nanodevices: A New Era in Biomedical Applications DOI Creative Commons
Mohammad Harun‐Ur‐Rashid, Israt Jahan, Tahmina Foyez

et al.

Micromachines, Journal Year: 2023, Volume and Issue: 14(9), P. 1786 - 1786

Published: Sept. 18, 2023

Exploring bio-inspired nanomaterials (BINMs) and incorporating them into micro/nanodevices represent a significant development in biomedical applications. Nanomaterials, engineered to imitate biological structures processes, exhibit distinctive attributes such as exceptional biocompatibility, multifunctionality, unparalleled versatility. The utilization of BINMs demonstrates potential diverse domains micro/nanodevices, encompassing biosensors, targeted drug delivery systems, advanced tissue engineering constructs. This article thoroughly examines the various BINMs, including those originating from proteins, DNA, biomimetic polymers. Significant attention is directed toward these entities subsequent ramifications that arise. review explores biomimicry’s structure–function correlations. Synthesis mosaics include bioprocesses, biomolecules, natural structures. These nanomaterials’ interfaces use functionalization geometric adaptations, transforming delivery, nanobiosensing, organ-on-chip cancer-on-chip models, wound healing dressing mats, antimicrobial surfaces. It provides an in-depth analysis existing challenges proposes prospective strategies improve efficiency, performance, reliability devices. Furthermore, this study offers forward-thinking viewpoint highlighting avenues for future exploration advancement. objective effectively utilize maximize application progression thereby propelling rapidly developing field its promising future.

Language: Английский

Citations

58

Green synthesis of metal oxide nanoparticles, and their various applications DOI Creative Commons
Uyiosa Osagie Aigbe, Otolorin Adelaja Osibote

Journal of Hazardous Materials Advances, Journal Year: 2024, Volume and Issue: 13, P. 100401 - 100401

Published: Jan. 13, 2024

Bio-synthesized metal oxide (MeO) nanoparticles (NPs) have triggered a huge global research interest owing to their advancement and various environmental remediation, personal care products, medical, energy, sensing, water treatment applications. They demonstrate developing assets in industries, remarkably with heightened physicochemical, optical, mechanical, electronic attributes. The physical chemical routes been sticking point the production of MeO NPs, natural risks linked utilizing these approaches. growth NPs via biologic method employing plants microorganisms as precursor material for metal-ions (MIs) reduction stabilization has focus scientists recent years. Hence, this review, comprehensive brief bio-synthesis approaches using plant extracts (PEs) microorganism components well factors affecting bio-production applications toxicity were considered.

Language: Английский

Citations

48

Green Synthesis of Silver Nanoparticles Using Salvia verticillata and Filipendula ulmaria Extracts: Optimization of Synthesis, Biological Activities, and Catalytic Properties DOI Creative Commons
Vladimir Mihailović, Nikola Srećković,

Zoran Nedić

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(2), P. 808 - 808

Published: Jan. 13, 2023

The study's objective was to obtain silver nanoparticles (SVAgNP and FUAgNP) using aqueous extracts of Salvia verticillata Filipendula ulmaria. optimal conditions for nanoparticle synthesis were determined obtained; then characterized UV-Vis, Fourier-transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), Dynamic Light Scattering (DLS), Scanning Electron Microscopy with Energy Dispersive Spectroscopy (SEM/EDS). SVAgNP FUAgNP possessed a crystalline structure 48.42% 60.41% weight, respectively. highest percentage in the solution had diameter between 40 70 nm. In DPPH˙ ABTS˙+ methods, (IC50 15.82 59.85 µg/mL, respectively) demonstrated higher antioxidant capacity than 73.47 79.49 respectively). Obtained also showed pronounced antibacterial activity (MIC ˂ 39.1 µg/mL most tested bacteria), as well high biocompatibility human fibroblast cell line MRC-5 significant cytotoxicity on some cancer lines, especially colon HCT-116 cells 31.50 66.51 FUAgNP, catalytic effectiveness degrading Congo red dye NaBH4. results rapid low-cost methodology AgNPs S. F. ulmaria promising biological potential.

Language: Английский

Citations

47

Precision-engineered metal and metal-oxide nanoparticles for biomedical imaging and healthcare applications DOI Creative Commons

Thi Thuy Truong,

Sudip Mondal,

Vu Hoang Minh Doan

et al.

Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 332, P. 103263 - 103263

Published: July 31, 2024

The growing field of nanotechnology has witnessed numerous advancements over the past few years, particularly in development engineered nanoparticles. Compared with bulk materials, metal nanoparticles possess more favorable properties, such as increased chemical activity and toxicity, owing to their smaller size larger surface area. Metal exhibit exceptional stability, specificity, sensitivity, effectiveness, making them highly useful biomedical field. are high demand nanotechnology, including Au, Ag, Pt, Cu, Zn, Co, Gd, Eu, Er. These particles excellent physicochemical amenable functionalization, non-corrosiveness, varying optical electronic properties based on shape. can be modified different targeting agents antibodies, liposomes, transferrin, folic acid, carbohydrates. Thus, hold great promise for various applications photoacoustic imaging, magnetic resonance computed tomography (CT), photothermal, photodynamic therapy (PDT). Despite potential, safety considerations, regulatory hurdles must addressed safe clinical applications. This review highlights nanoparticle engineering explores integration emerging technologies bioimaging, cancer therapeutics nanomedicine. By offering valuable insights, this comprehensive offers a deep understanding potential research.

Language: Английский

Citations

43

A critical review on metal-organic frameworks (MOFs) based nanomaterials for biomedical applications: Designing, recent trends, challenges, and prospects DOI Creative Commons
Samreen Sadiq, Shoaib Khan, Iltaf Khan

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(3), P. e25521 - e25521

Published: Feb. 1, 2024

Nanomaterials (NMs) have garnered significant attention in recent decades due to their versatile applications a wide range of fields. Thanks tiny size, enhanced surface modifications, impressive volume-to-surface area ratio, magnetic properties, and customized optical dispersion. NMs experienced an incredible upsurge biomedical including diagnostics, therapeutics, drug delivery. This minireview will focus on notable examples that tackle important issues, demonstrating various aspects such as design, synthesis, morphology, classification, use cutting-edge applications. Furthermore, we classified outlined the distinctive characteristics advanced nanoscale particles hybrid NMs. Meanwhile, emphasize potential metal-organic frameworks (MOFs), highly group These MOFs gained recognition promising candidates for bio-applications, bioimaging, biosensing, antiviral therapy, anticancer nanomedicines, theranostics, immunotherapy, photodynamic photothermal gene Although shown great field, clinical is still limited by issues stability, cytotoxicity, biocompatibility, health concerns. review article provides thorough analysis offering valuable insights researchers investigating explore new development, expansion opportunities. Remarkably, ponder prospects nanocomposites conjunction with current technology.

Language: Английский

Citations

29

Metal and metal oxide nanoparticles combined with ionic liquids and deep eutectic solvents and their practices in drug extraction and environmental processes: A review DOI
Noureddine El Messaoudi, Funda Aydın, Youssef Miyah

et al.

Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: unknown, P. 126955 - 126955

Published: Jan. 1, 2025

Language: Английский

Citations

2