A Multifunctional Capsule-like Puncture Biopsy Robot for the Gastrointestinal System DOI Creative Commons

Xinmiao Xu,

Jinghan Gao,

Dingwen Tong

et al.

Micromachines, Journal Year: 2025, Volume and Issue: 16(5), P. 589 - 589

Published: May 18, 2025

Gastrointestinal submucosal tumors (SMTs) are difficult to diagnose accurately due their deep location and the limitations of traditional biopsy tools. To address these issues, we propose a multifunctional capsule-shaped puncture robot (PBR) with capabilities for tissue sampling, thermal hemostasis, multi-stage drug delivery. The PBR measures 27 mm in length 13 diameter, integrating micro-scale electro-permanent magnetic system 60-turn dual-layer coil (wire diameter: 0.6 mm) drive an 8 mm-depth needle. A graphene–carbon nanotube composite heating film enables rapid safe temperature elevation, achieving effective hemostasis triggering sequential release using paraffin-based phase-change materials. Heating remains within clinical safety range. Experiments demonstrated successful penetration, precise control, reliable staged pigment simulating Tests on ex vivo porcine stomach confirmed adaptability irregular gastric surfaces. This compact provides integrated minimally invasive approach both diagnosis treatment gastrointestinal lesions.

Language: Английский

Understanding the Functionality of Probiotics on the Edge of Artificial Intelligence (AI) Era DOI Creative Commons
Remziye Asar,

Sinem Erenler,

Dilara Devecioğlu

et al.

Fermentation, Journal Year: 2025, Volume and Issue: 11(5), P. 259 - 259

Published: May 5, 2025

This review focuses on the potential utilization of artificial intelligence (AI) tools to deepen our understanding probiotics, their mode action, and technological characteristics such as survival. To that end, this provides an overview current knowledge probiotics well next-generation probiotics. AI-aided omics technologies, including genomics, transcriptomics, proteomics, offer new insights into genetic functional properties Furthermore, AI can be used elucidate key probiotic activities microbiota modulation, metabolite production, immune system interactions enable improved health impacts. Additionally, technologies facilitate precision in identifying impacts, role gut health, anticancer activity, antiaging effects. Beyond applications, expand use optimizing storage survival broadening biotechnological approaches. In context, addresses how AI-driven approaches facilitated by strengthening evaluation characteristics, explaining mechanisms enhancing applications. Moreover, enhance impact assessments optimize industrial applications is highlighted, concluding with future perspectives transformative research.

Language: Английский

Citations

0

A Multifunctional Capsule-like Puncture Biopsy Robot for the Gastrointestinal System DOI Creative Commons

Xinmiao Xu,

Jinghan Gao,

Dingwen Tong

et al.

Micromachines, Journal Year: 2025, Volume and Issue: 16(5), P. 589 - 589

Published: May 18, 2025

Gastrointestinal submucosal tumors (SMTs) are difficult to diagnose accurately due their deep location and the limitations of traditional biopsy tools. To address these issues, we propose a multifunctional capsule-shaped puncture robot (PBR) with capabilities for tissue sampling, thermal hemostasis, multi-stage drug delivery. The PBR measures 27 mm in length 13 diameter, integrating micro-scale electro-permanent magnetic system 60-turn dual-layer coil (wire diameter: 0.6 mm) drive an 8 mm-depth needle. A graphene–carbon nanotube composite heating film enables rapid safe temperature elevation, achieving effective hemostasis triggering sequential release using paraffin-based phase-change materials. Heating remains within clinical safety range. Experiments demonstrated successful penetration, precise control, reliable staged pigment simulating Tests on ex vivo porcine stomach confirmed adaptability irregular gastric surfaces. This compact provides integrated minimally invasive approach both diagnosis treatment gastrointestinal lesions.

Language: Английский

Citations

0