Current Status and Perspectives of Research on Polymer Hydrogels in the Treatment and Protection of Osteoarthritis DOI
Wanjun Liang, Ruey‐Jen Yang,

Lijing Qin

et al.

Macromolecular Bioscience, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Abstract Arthritis is a degenerative disease characterized by chronic cartilage degeneration. It affects hundreds of millions people worldwide and often has serious consequences such as joint pain swelling, limited mobility, deformity. However, conventional treatments still struggle to achieve satisfactory results. Finding more effective for arthritis remains an important clinical challenge. As hydrogels have unique 3D spatial mesh structure, significant material interaction ability, adjustable mechanical properties, good biodegradability, they can provide suitable cellular or tissue microenvironment, their potential in scaffolding effect, lubrication, anti‐inflammatory drug delivery expected be potent therapeutic approach the treatment osteoarthritis. In this review, three aspects hydrogel products osteoarthritis are comprehensively summarized discussed, namely, selection gel design, exploration cross‐linking mechanisms, mechanisms therapy osteoarthritis, focus on advantages limitations applications, which point out direction development strategy innovative field, applied research, transformation.

Language: Английский

Biomimetic hydrogel periodontal membrane coating with mechanical compatibility for dental implant DOI

Yong Shao,

Tingting Kong, Yujun Zhang

et al.

Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 105959 - 105959

Published: Feb. 1, 2025

Language: Английский

Citations

0
Traditional Chinese Medicine-Loaded Hydrogels: An Emerging Strategy for the Treatment of Bone Infections DOI Creative Commons
Xin Jin,

Yuchen Yue,

Huaanzi Hu

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(4), P. 514 - 514

Published: April 14, 2025

Bone infection is a disease that seriously affects patients’ quality of life and physical health. Traditional treatment methods have many drawbacks. Hydrogels loaded with Chinese Medicine (TCM), as an emerging strategy, combine the advantages good biocompatibility hydrogels, adjustable drug release performance, multi-target synergistic TCM, showing great application potential. This article elaborates in detail on research progress hydrogels TCM for bone infections, including classification characteristics mechanism action preparation examples, advantages, challenges prospects faced. The aim to provide new ideas references clinical infections.

Language: Английский

Citations

0
Current Status and Perspectives of Research on Polymer Hydrogels in the Treatment and Protection of Osteoarthritis DOI
Wanjun Liang, Ruey‐Jen Yang,

Lijing Qin

et al.

Macromolecular Bioscience, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Abstract Arthritis is a degenerative disease characterized by chronic cartilage degeneration. It affects hundreds of millions people worldwide and often has serious consequences such as joint pain swelling, limited mobility, deformity. However, conventional treatments still struggle to achieve satisfactory results. Finding more effective for arthritis remains an important clinical challenge. As hydrogels have unique 3D spatial mesh structure, significant material interaction ability, adjustable mechanical properties, good biodegradability, they can provide suitable cellular or tissue microenvironment, their potential in scaffolding effect, lubrication, anti‐inflammatory drug delivery expected be potent therapeutic approach the treatment osteoarthritis. In this review, three aspects hydrogel products osteoarthritis are comprehensively summarized discussed, namely, selection gel design, exploration cross‐linking mechanisms, mechanisms therapy osteoarthritis, focus on advantages limitations applications, which point out direction development strategy innovative field, applied research, transformation.

Language: Английский

Citations

0