European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 272, P. 116474 - 116474
Published: May 3, 2024
Language: Английский
European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 272, P. 116474 - 116474
Published: May 3, 2024
Language: Английский
Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 488, P. 137452 - 137452
Published: Feb. 3, 2025
Language: Английский
Citations
2Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: 332, P. 125831 - 125831
Published: Jan. 31, 2025
Language: Английский
Citations
1Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 271, P. 117067 - 117067
Published: Dec. 14, 2024
Language: Английский
Citations
4Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: 338, P. 126176 - 126176
Published: April 6, 2025
Language: Английский
Citations
0Dyes and Pigments, Journal Year: 2024, Volume and Issue: 228, P. 112196 - 112196
Published: May 1, 2024
Language: Английский
Citations
1Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 6, 2024
This review highlights the current advancements in development of fluorescent probes for selective detection disease-relevant enzymes, focusing on their biocompatibility vivo models.
Language: Английский
Citations
1Journal of Fluorescence, Journal Year: 2024, Volume and Issue: unknown
Published: June 17, 2024
Language: Английский
Citations
0RSC Advances, Journal Year: 2024, Volume and Issue: 14(50), P. 37311 - 37321
Published: Jan. 1, 2024
A novel triphenylamine-based dicyano fluorophore (compound 2) was successfully synthesized using a Suzuki cross-coupling reaction, followed by Knoevenagel condensation catalyzed with baker's yeast.
Language: Английский
Citations
0Applied Sciences, Journal Year: 2024, Volume and Issue: 14(23), P. 10856 - 10856
Published: Nov. 23, 2024
Monoamine oxidase A (MAO-A) is the main enzyme that deaminates serotonin. Correct serotonin concentration regulates appetite, improves well-being, reduces symptoms of depression, but also memory and heart function. In this study, use new compounds chemo-enzymatically synthesized from propenylbenzene derivatives as MAO-A inhibitors was proposed. Isothermal titration calorimetry analysis molecular modeling were used to determine inhibitory effect MAO-A. The such propenylbenzenes observed have no effect. However, in case diols hydroxy ketones, showed effects. particular, 1-(4-hydroxy-3-methoxyphenyl)propane-1,2-diol, both isothermal (ITC) modeling, high affinity for enzyme, thus protecting deamination. results suggest derivatives, bind at active site. This suggests their potential be drugs or food supplements prevent depression. These studies may constitute a tool further vivo vitro studies.
Language: Английский
Citations
0European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 272, P. 116474 - 116474
Published: May 3, 2024
Language: Английский
Citations
0