Antifouling and Bactericidal Zwitterionic Polymer Coatings with Synergistic Inhibitory and Killing Properties

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 22, 2025

Polymeric coatings that combine resistance to adhesion ("defending") and killing ("attacking") of biocontaminants were proposed endow the surface with nonadhesive bactericidal capabilities. In contrast, a zwitterionic copolymer P(GMA-co-DMAPS) antifouling groups ([2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide, DMAPS) zwitterionic/cationic P(GMA-co-DMAPS-co-DMC) ([2-(methacryloyloxy)ethyl]trimethylammonium chloride, DMC) synthesized, which latter exhibited synergistic inhibitory properties. The distinct feed ratios monomers conducted, optimal molar ratio was obtained. polymer coating chemically bonded substrates such as stainless steel via addition–elimination reaction epoxy hydroxyl groups. Stainless surfaces grafted G20D80-5DMC fine results showed highly efficient defending–attacking effect achieved antiprotein adsorption more than 90% rates against Staphylococcus aureus Escherichia coli 98.6% 96.6%, respectively. polymers in this study can effectively play an antibacterial role be onto through simple effective method, showing attractive potential marine, biomedical, industrial applications.

Language: Английский

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Interpenetrating Polymer Networks in Biomedical Fields: Recent Advanced and Applications

Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(2)

Published: Feb. 1, 2025

ABSTRACT Recent developments in polymer materials have led to an increased implementation of hydrogels biomedical settings, especially the creation smart hydrogels. Traditional single‐network often exhibit challenges, such as poor mechanical strength, insufficient biocompatibility, and slow response rates. To address these issues, researchers introduced Interpenetrating Polymer Network (IPN) hydrogels, which significantly improve strength via topological entanglements physical interactions. This dual‐network design not only enhances biocompatibility but also responsiveness stimuli, endowing with distinctive properties like cell adhesion, conductivity, hemostatic functions, antioxidant abilities, color‐changing properties. The purpose this article is elucidate factors that trigger stimuli IPN their impacts on cellular behavior, various applications they can serve. A comprehensive overview provided regarding classification, mechanisms, performance attributes, related subjects. Ultimately, review emphasizes promise hold fulfilling increasing need for innovative improved features sector.

Language: Английский

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Recent Updates on Blood Purification: Use of Smart Polymer Materials

Journal of Biomedical Materials Research Part A, Journal Year: 2025, Volume and Issue: 113(3)

Published: Feb. 24, 2025

Blood purification is indispensable in addressing various conditions such as liver dysfunction, autoimmune diseases, and renal failure whereby toxins have to be cleared from the bloodstream effectively. Conventional methods that involve hemoperfusion, hemodialysis, hemofiltration possess several weaknesses, including loss of plasma components inefficient clearance high molecular weight solutes. This review explores current developments blood techniques particularly stimuli-responsive polymers for use extracorporeal therapy among other applications. Many aspects engineering are described terms their role removal small soluble molecules techniques. The development systems has introduced a new paradigm by enabling selective, on-demand control polymer parameters response external stimuli temperature, pH, electrolytes, light. Such advanced materials been demonstrated potential toxin clearance, minimizing thrombosis, improving compatibility antifouling, which far much better than traditional approaches. Furthermore, presents perspective on could used developing novel future medical purposes.

Language: Английский

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One-Step Zwitterionic Modification of Polyamide–Polyurethane Mixed Textile through Acidic Catalyzation

Langmuir, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

In this study, a straightforward one-step zwitterionic surface modification technique was developed for polyamide materials and fiber products, providing excellent antibiofouling properties. The of (PA) polyurethane (PU) modified using an epoxy-type biomimetic copolymer, poly(glycidyl methacrylate-co-sulfobetaine acrylamide) (PGSA), composed glycidyl methacrylate sulfobetaine acrylamide through acidic-catalyzed dip-coating method. Under acidic conditions, the molecular chains were activated, exposing terminal amine groups that facilitated reactivity, enabling copolymer to undergo ring-opening addition reactions. optimization coating parameters, including reaction temperature, solid concentration, molar ratio, pH conducted achieve optimal performance. fabric demonstrated enhanced biocompatibility capabilities, 70% reduction fibrinogen adsorption, 93% whole-blood cell attachment, 95% red blood 98.2% bacterial attachment. This simple cost-effective technology surfaces holds significant potential biomedical device functional textile applications.

Language: Английский

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Mechanistic insights into enhancing water transport and antifouling performance under high concentration polarization in polyamide membranes

Journal of Membrane Science, Journal Year: 2025, Volume and Issue: unknown, P. 124060 - 124060

Published: April 1, 2025

Language: Английский

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ML‐based Read‐Across Structure‐Property Relationship (RASPR) strategy for Predicting Protein Resistance of Self-Assembled Monolayers (SAMs) as anti-biofouling materials

Materials Today Communications, Journal Year: 2024, Volume and Issue: unknown, P. 111089 - 111089

Published: Nov. 1, 2024

Language: Английский

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Research Progress on Implantable Medical Textiles and Their Surface Functional Coatings

Journal of Polymer Science, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 25, 2024

ABSTRACT With changes in people's lifestyles and the escalating pace of population aging, incidence rate chronic diseases has increased annually, posing significant challenges to both individual societal health. Specifically engineered implantable medical textiles have exhibited structural superiority over other material types repairing or replacing damaged tissues organs within body, along with enhancement their functions. They also play important roles treatment management diseases. This review takes several representative textiles, such as artificial blood vessels, ligaments, sutures, examples introduce fundamental features particularities inherent development. In addition, on basis clinical requirements anti‐infection, common strategies for construction antibacterial coatings are summarized. Ultimately, development trend is discussed. Through this review, we aim provide certain insights conception novel textiles.

Language: Английский

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