
Molecules, Journal Year: 2025, Volume and Issue: 30(5), P. 1041 - 1041
Published: Feb. 25, 2025
Piezoelectric materials, due to their ability generate an electric charge in response mechanical deformation, are becoming increasingly attractive the engineering of bone and neural tissues. This manuscript reports effects addition nanohydroxyapatite (nHA), introduction gold nanoparticles (AuNPs) via sonochemical coating, collector rotation speed on formation electroactive phases biological properties electrospun nanofiber scaffolds consisting poly(vinylidene fluoride) (PVDF). FTIR, WAXS, DSC, SEM results indicate that nHA increases content fiber alignment. The rotational not only alignment but also PVDF PVDF/nHA fibers. Increased orientation each additives resulted increased SFE water uptake. In vitro tests conducted MG-63 hiPSC-NSC cells showed adhesion cell proliferation. PVDF-based composites with AuNPs promising candidates for development advanced tissue applications, combining electrical functionality activity support regeneration.
Language: Английский