A tissue regeneration-promoting hydrogel dressing incorporating zirconium MOF loaded with curcumin for multi-modal healing of bacterial-infected wounds

Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 44, P. 102568 - 102568

Published: Feb. 9, 2025

Language: Английский

Responsive nanomaterials in biomedicine, patent path and prospect analysis

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 4, 2025

In recent years, responsive nanomaterials have demonstrated tremendous potential in biomedical applications due to their unique advantages precise drug delivery and controlled release. For complex diseases such as cancer, chronic inflammation, genetic disorders, traditional treatment methods are often limited by insufficient targeting significant side effects. Responsive nanotechnology, sensing specific internal or external stimuli, has significantly enhanced the precision efficiency of treatments. This study systematically summarizes technological trajectory emerging research directions through global patent literature data, employing main path analysis, derivative keyword co-occurrence analysis. The results reveal evolution this field, from optimization early single-stimulus-responsive nano systems rise theranostics integration, followed advancements multi-stimuli-responsive synergistic therapies, finally, innovation biomimetic material design. Each developmental phase increasingly focused on adapting biological environments, achieving superior performance, enhancing therapeutic efficacy. Keyword analysis highlights key hotspots, including design, multimodal response mechanisms. future, expected play a pivotal role personalized medicine, multifunctional carrier disease management, providing novel insights support for medicine.

Language: Английский

Diffusion Dynamics of Rhodamine B Through Layered Silk Fibroin Hydrogels Reinforced with Polyethylene Terephthalate Nonwoven Textile

E3S Web of Conferences, Journal Year: 2024, Volume and Issue: 588, P. 03004 - 03004

Published: Jan. 1, 2024

This study investigates the kinetics of rhodamine B diffusion over a multilayer membrane composed silk fibroin hydrogel and polyethylene terephthalate (PET) nonwoven fabric. To evaluate impact varying structure thicknesses on dye rate, we used 2, 4, 8, 16, 32 layers. The research indicated that 32-layer significantly slowed penetration. An initial linear release was seen until 2500 minutes, after which rate decelerated. Validation controlled behavior across layers achieved by UV-Vis spectroscopic analysis, specifically targeting absorbance peak at 554 nm B. results this provide crucial insights for advancement hydrogel- based materials in sensor technologies, drug delivery approaches, regulated release.

Language: Английский