Journal of university of Anbar for pure science,
Journal Year:
2024,
Volume and Issue:
18(1), P. 152 - 164
Published: June 1, 2024
The
increasing
resistance
of
microorganisms
to
commonly
used
antibiotics
has
become
a
significant
public
health
problem.
To
address
this
issue,
new
approaches
are
urgently
needed
combating
these
types
pathogenic
microbes.
Nanoscience
led
the
development
novel
antibacterial
materials
including
metal
nanoparticles
like
silver,
zinc,
copper,
gold,
nickel,
magnesium,
iron,
titanium,
palladium
selenium
and
aluminum.
These
have
shown
bactericidal
properties
against
wide
range
multi-drug
resistant
bacterial
strains.
Metal
physically
disrupt
inactivate
various
cellular
contents
without
effected
by
mechanisms.
Nanomaterials
small
size,
prolonged
effectiveness,
low
toxicity
contribute
reduce
environmental
hazards.
However,
scientists
need
several
challenges,
bioethical
concerns,
risks
toxicity,
physiological
medical
considerations
associated
with
use
nanomaterials
as
drugs.
Due
lack
mechanisms
nanoparticles,
we
could
see
molecules
replacing
in
treatment
bacteria.
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 12889 - 12937
Published: Dec. 1, 2024
Abstract:
Over
the
last
decade,
biomedical
nanomaterials
have
garnered
significant
attention
due
to
their
remarkable
biological
properties
and
diverse
applications
in
biomedicine.
Metal
oxide
nanoparticles
(NPs)
are
particularly
notable
for
wide
range
of
medicinal
uses,
including
antibacterial,
anticancer,
biosensing,
cell
imaging,
drug/gene
delivery.
Among
these,
zinc
(ZnO)
NPs
stand
out
versatility
effectiveness.
Recently,
ZnO
become
a
primary
material
various
sectors,
such
as
pharmaceutical,
cosmetic,
antimicrobials,
construction,
textile,
automotive
industries.
can
generate
reactive
oxygen
species
induce
cellular
apoptosis,
thus
underpinning
potent
anticancer
antibacterial
properties.
To
meet
growing
demand,
numerous
synthetic
approaches
been
developed
produce
NPs.
However,
traditional
manufacturing
processes
often
involve
economic
environmental
costs,
prompting
search
more
sustainable
alternatives.
Intriguingly,
synthesis
methods
utilizing
plants,
plant
extracts,
or
microorganisms
emerged
ideal
producing
These
green
production
techniques
offer
medicinal,
economic,
environmental,
health
benefits.
This
review
highlights
latest
advancements
applications,
showcasing
potential
revolutionize
field
with
eco-friendly
cost-effective
solutions.
Keywords:
antimicrobial,
antioxidant,
synthesis,
nanomedicine,
nanoparticle,
OpenNano,
Journal Year:
2024,
Volume and Issue:
19, P. 100212 - 100212
Published: Aug. 15, 2024
Medical
companies
and
research
centers
seek
cost-effective
alternative
culture
media
containing
the
necessary
nutritional
requirements
for
bacterial
cultivation
because
of
high
manufacturing
production
costs.
Date
palm
pollen
(DPP)
is
an
inexpensive
rich
natural
plant
resource
that
can
be
easily
collected
in
large
quantities.
In
this
study,
DPP
was
used
to
prepare
a
novel
enriched
medium
successfully
cultivated
pathogenic
bacteria
Streptomyces
spp.
without
any
additives
at
low
concentration
10
g
per
1
L
distilled
water
(DW).
Active
compounds
were
detected
by
GCMS–,
results
show
highest
ratio
urea
(45
%)
among
other
components.
For
first
time,
synthesize
Cr2O3
NPs
environment-friendly
green
method.
plays
important
role
as
reducing
stabilizing
agent
biosynthesis
NPs.
The
obtained
characterized
using
UV–Vis,
FTIR,
XRD
SEM.
agar
disk
diffusion
ranging
between
12
–
20
mm
while
MIC
1.56
25
U/mL
indicated
effectiveness
antibacterial
activity
against
wide
range
bacteria.
showed
inhibition
reach
78
%
biofilms
produced
P.
aeruginosa.
later
studies
we
expect
selective
after
adding
certain
materials
or
antibiotics.
anti-biofilm
could
promising
medical
pharmaceutical
applications.
