Two New Inner-sphere Pt(II) Thiosemicarbazone Schiff Base Complexes Immobilized into Magnetic Nanoparticles: Synthesis, Characterization, and Biological Investigations DOI

Asmaa W. Abo El-Ata,

Mohammed M. El‐Gamil, Yasmeen G. Abou El‐Reash

et al.

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 170, P. 113366 - 113366

Published: Oct. 22, 2024

Language: Английский

Unveiling the Ameliorative Effects of Phyto-selenium Nanoparticles (PSeNPs) on Anti-hyperglycemic Activity and Hyperglycemia Irradiated Complications DOI
Ushasi Das, Suraj N. Mali, Sanchita Mandal

et al.

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)

Published: Feb. 10, 2025

Language: Английский

Citations

1
Navigating Tumor Microenvironment Barriers with Nanotherapeutic Strategies for Targeting Metastasis DOI
Monica A. Thomas,

Anjana Kaveri Badekila,

V. D. Pai

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 22, 2025

Abstract Therapeutic strategy for efficiently targeting cancer cells needs an in‐depth understanding of the cellular and molecular interplay in tumor microenvironment (TME). TME comprises heterogeneous clustered together to translate initiation, migration, proliferation. The mainly proliferating cells, stromal blood vessels, lymphatic cancer‐associated fibroblasts (CAFs), extracellular matrix (ECM), stem (CSC). heterogeneity genetic evolution metastatic tumors can substantially impact clinical effectiveness therapeutic agents. Therefore, shall target all stages. Since advent nanotechnology, smart drug delivery strategies are employed deliver effective formulations directly into tumors, ensuring controlled sustained efficacy. state‐of‐the‐art nano‐drug systems shown have innocuous modes action players TME. this review provides insight mechanism metastasis involving invasion, intravasation, systemic transport circulating (CTCs), extravasation, colonization, angiogenesis. Further, novel perspectives associated with current nanotherapeutic highlighted on different stages metastasis.

Language: Английский

Citations

0
Demystifying the Potential of Polymeric Lipids as Substitute in Regenerative Applications: A Review DOI Open Access
Popat Mohite, Abhijeet Puri, Deepak Bharati

et al.

Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(2)

Published: Feb. 1, 2025

ABSTRACT The objective of a regenerative medicine is to repair, restore, and regenerate tissues organs that occurred due injury or defect disease. Additionally, the purpose reverse aging process body by utilizing body's innate healing ability. There still significant venture needs be directed for advancement in arena medicine, which makes use products derived from cell therapy as well biomedical. Stem cells growth factors are primary components medicine; hence, novel drug delivering systems now being studied augment transport active pharmaceuticals. Lipid‐based complexed with therapeutics suited site‐specific controlled release. Lipids biocompatible available various sources molecular weights self‐assemble into forms hydrophilic hydrophobic parts. By enhancing plasma membrane fluidity, excipients such non‐ionic surfactants, fatty acids, glycerides increase permeability. Liposomes, nanoparticles, nano‐emulsions, micelles nano‐lipid carriers can improve bioavailability both lipophilic medicines. lipoidal‐polymeric had emerged promising multifaceted application cytocompatibility, ecofriendly, ability encapsulate variety drugs. Further, treatment biomedical tissue engineering, rapidly developing discipline. Furthermore, similar vein, delivery technologies combined stem promote engraftment, differentiation, survival. Hence colloidal carrier has impending versatile applications. Therefore, review offer an abridged information on significance technology offering confined ecosystem facilitates them thrive distinguish effective manner.

Language: Английский

Citations

0
Potential of Carbon Nanodots (CNDs) in Cancer Treatment DOI Creative Commons

Walaa Alibrahem,

Nihad Kharrat Helu,

Csaba Oláh

et al.

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(7), P. 560 - 560

Published: April 6, 2025

Carbon Nanodots (CNDs) are characterized by their nanoscale size (<10 nm), biocompatibility, stability, fluorescence, and photoluminescence, making them a promising candidate for cancer therapy. The difference in the methods of synthesis CNDs, whether top-down or bottom-up, affects formation, visual, surface characteristics which crucial biomedical pharmaceutical applications. urgent need innovative therapeutic strategies from CNDs is due to limitations barriers posed conventional therapies including drug resistance cytotoxicity. Nano-loaded chemotherapy treatments highly effective can enhance solubility targeted delivery chemotherapeutic agents, generate reactive oxygen species (ROS) induce cell cytotoxicity, regulate intracellular signaling pathways. Their ability be designed cellular uptake exact localization further improves potential. In addition working on delivery, highlighted dual functionality imaging therapy, allows real-time observing treatment efficacy. Despite development these results future, challenges still exist treatment.

Language: Английский

Citations

0
Demystifying the management of cancer through smart nano-biomedicine via regulation of reactive oxygen species DOI
Abhay Prakash Mishra,

Rajesh Kumar,

Seetha Harilal

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: 398(1), P. 497 - 532

Published: Oct. 31, 2024

Language: Английский

Citations

1
Two New Inner-sphere Pt(II) Thiosemicarbazone Schiff Base Complexes Immobilized into Magnetic Nanoparticles: Synthesis, Characterization, and Biological Investigations DOI

Asmaa W. Abo El-Ata,

Mohammed M. El‐Gamil, Yasmeen G. Abou El‐Reash

et al.

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 170, P. 113366 - 113366

Published: Oct. 22, 2024

Language: Английский

Citations

0