International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 135353 - 135353
Published: Sept. 7, 2024
Language: Английский
Small Science, Journal Year: 2023, Volume and Issue: 4(1)
Published: Nov. 27, 2023
Nanomaterials with diagnostic and therapeutic functions have exciting potential to reshape the landscape of precision medicine. Impressive progress has been made toward design production innovative theranostic nanomaterials that improve disease care, motivated by their ability simultaneously provide information benefits. Herein, state‐of‐the‐art semiconductor quantum dots (QDs) are summarized, diverse types QDs designed for diagnosis treatment different diseases discussed. The opportunities benefits highlighted throughout using in vitro vivo examples aimed at addressing various clinical challenges, including cancer, vascular dysfunctions, microbial infections, medical tattoos. Over past several years, this area experienced enormous growth, particularly preclinical animal imaging therapy, which brought field closer reaching human patients. Unfortunately, barriers translation remain. Therefore, addition summarizing key results from previous studies, lessons learned these studies synthesized, perspective on future steps needed both fundamental QD nanotechnology inform is provided.
Language: Английский
Citations
5
Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(14), P. 3550 - 3564
Published: Jan. 1, 2024
This review summarizes different types of DNA response elements and highlights the advancements in element-based smart drug delivery systems for precise release.
Language: Английский
Citations
1
Advanced Sensor and Energy Materials, Journal Year: 2024, Volume and Issue: 3(4), P. 100117 - 100117
Published: July 30, 2024
Spherical nucleic acids (SNAs) are a 3D spherical nanostructure composed of highly oriented, dense layers oligonucleotides conjugated to hollow or solid core. This structure allows SNAs show resistance nuclease degradation, enter into nearly all cells without transfection agents and enable precise interactions with target molecules. Based on superior biological properties, can be tailored for diverse applications, rendering them flexible biosafe tool applications as well an enabling platform therapy. In this review, we mainly discuss the conjugation mode focus recent advances in their such biomedical detection, imaging, drug delivery. Finally, remaining challenges future directions also discussed proposed.
Language: Английский
Citations
1
Nanoscale, Journal Year: 2024, Volume and Issue: 16(15), P. 7690 - 7699
Published: Jan. 1, 2024
Plasmonic nanostructures can be used to enhance the efficiency of upconversion nanoparticles (UCNPs) and enable new functionalities. However, fabrication these hybrid plasmon-UCNP has traditionally relied on either wet chemistry or nanolithography routes that are difficult control, scale up, both. In this work, we present a scalable nanofabrication process, capable producing massive array gold-UCNP over few mm2 area with excellent uniformity in photoluminescence intensity. This approach combines scalability bottom-up self-assembly method precision top-down approach. It provides an efficient alternative route for production plasmonically enhanced UCNPs. A detailed discussion optimization UCNP self-assembly, gold nanodisk lithography, nanopattern transfer processes is presented here. Additionally, showcase potential fabricating mechanical force sensors based selective plasmonic enhancement emission. holds great facilitating UCNPs deployed both imaging sensing applications.
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 135353 - 135353
Published: Sept. 7, 2024
Language: Английский
Citations
0