The potential use of nanozymes as an antibacterial agents in oral infection, periodontitis, and peri-implantitis

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: April 25, 2024

Abstract Several studies suggest that oral pathogenic biofilms cause persistent infections. Among these is periodontitis, a prevalent condition brought on by plaque biofilm. It can even result in tooth loss. Furthermore, the accumulation of germs around dental implant may lead to peri-implantitis, which damages surrounding bone and gum tissue. bacterial biofilm contamination causes soft tissue irritation adjacent resorption, severely compromising health. On decontaminated surfaces, however, re-osseointegration cannot be induced standard removal techniques such as mechanical cleaning antiseptic treatment. A family nanoparticles known nanozymes (NZs) comprise highly catalytically active multivalent metal components. The most often employed NZs with antibacterial activity are those have peroxidase (POD) activity, among other types NZs. Since less expensive, more easily produced, stable than natural enzymes, they hold great promise for use various applications, including treating microbial significantly contributed studying success rates periodontal health maintenance periodontics implantology. An extensive analysis research their applications managing conditions, caries, pulp disorders, ulcers, infections mouth. To combat bacteria, this review concentrates imitate enzymes implantology periodontology. With view future, there several ways might used treat disorders antibacterially. Graphical

Language: Английский

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Cariogenic Microbiota and Emerging Antibacterial Materials to Combat Dental Caries: A Literature Review

Pathogens, Journal Year: 2025, Volume and Issue: 14(2), P. 111 - 111

Published: Jan. 23, 2025

Dental caries is the most common oral disease in world and a chronic infectious disease. The cariogenic microbiome plays an important role process of caries. ecological imbalance microbiota leads to low pH, which causes Therefore, antibacterial materials have always been hot topic. Traditional such as cationic agents, metal ion some natural extract agents good effects. However, they can cause bacterial resistance poor biological safety when used for long-term purposes. Intelligent materials, pH-responsive nanozymes, photoresponsive piezoelectric living are emerging nano-strategies that respond microenvironment or other specific stimuli exert Compared with traditional these less prone resistanceand safety. This review summarizes characteristics materials. These accurately act on microenvironment, showing intelligent effects providing new ideas management.

Language: Английский

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An injectable gelatin methacrylate containing surface-imprinted chitosan-modified bioglass microspheres for potential periodontitis treatment

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 302, P. 140561 - 140561

Published: Jan. 31, 2025

Language: Английский

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Saliva-acquired pellicle inspired multifunctional gargle with wet adhesion, photodynamic antimicrobial, and In situ remineralization properties for dental caries prevention

Bioactive Materials, Journal Year: 2025, Volume and Issue: 47, P. 212 - 228

Published: Jan. 23, 2025

Language: Английский

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Review of carbonaceous nanoparticles for antibacterial uses in various dental infections

Nanotoxicology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 36

Published: Jan. 30, 2025

The mouth cavity is the second most complex microbial community in human body. It composed of bacteria, viruses, fungi, and protozoa. An imbalance oral microbiota may lead to various conditions, including caries, soft tissue infections, periodontitis, root canal peri-implantitis (PI), pulpitis, candidiasis, denture stomatitis. Additionally, several locally administered antimicrobials have been suggested for dentistry surgical non-surgical applications. main drawbacks are increased antimicrobial resistance, risk upsetting natural microbiota, hypersensitivity responses. Because their unique physiochemical characteristics, nanoparticles (NPs) can circumvent antibiotic-resistance mechanisms exert action via a variety new bactericidal routes. anti-microbial properties, carbon-based NPs becoming more effective antibacterial agents. Periodontitis, PI, dentin other dental diseases among conditions that be treated using carbon (CNPs) like graphene oxide dots. outline scientific development multifunctional CNPs concerning disorders will given before talking about significant influence on health. Some these illnesses include pulp disorders, PI. We also review remaining research application barriers possible future problems.

Language: Английский

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Yellow light and ultrasound Dual-responsive strontium-doped zinc oxide composites for dental caries prevention and remineralization

Bioactive Materials, Journal Year: 2025, Volume and Issue: 47, P. 403 - 416

Published: Feb. 12, 2025

Language: Английский

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Streptococcus mutans biofilms in the establishment of dental caries: a review

3 Biotech, Journal Year: 2025, Volume and Issue: 15(3)

Published: Feb. 14, 2025

Language: Английский

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Expert consensus on the prevention and treatment of enamel demineralization in orthodontic treatment

International Journal of Oral Science, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 28, 2025

Abstracts Enamel demineralization, the formation of white spot lesions, is a common issue in clinical orthodontic treatment. The appearance lesions not only affects texture and health dental hard tissues but also impacts aesthetics teeth after prevention, diagnosis, treatment that occur throughout process involve multiple specialties. This expert consensus will focus on providing guiding opinions management prevention during treatment, advocating for proactive early detection, timely scientific follow-up, multidisciplinary process, thereby maintaining patients

Language: Английский

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Graphdiyne biomaterials: from characterization to properties and applications

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: March 4, 2025

Graphdiyne (GDY), the sole synthetic carbon allotrope with sp-hybridized atoms, has been extensively researched that benefit from its pore structure, fully conjugated surfaces, wide band gaps, and more reactive C≡C bonds. In addition to intrinsic features of GDY, engineering at nanoscale, including metal/transition metal ion modification, chemical elemental doping, other biomolecular modifications, endowed GDY a broader functionality. This led involvement in biomedical applications, enzyme catalysis, molecular assays, targeted drug delivery, antitumor, sensors. These promising research developments have made possible by rational design critical characterization biomaterials. contrast areas, biomaterials development techniques methods specific patterns some innovations based on integration materials science biology, which are crucial for applications GDY. The objective this review is provide comprehensive overview essential process. Additionally, general strategy will be proposed, limited help researchers field or nanomedicine.

Language: Английский

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Graphdiyne surface-modified CuS-GDY/LaCoO3 S-scheme heterojunctions for enhanced photocatalytic hydrogen evolution

Separation and Purification Technology, Journal Year: 2024, Volume and Issue: unknown, P. 129831 - 129831

Published: Sept. 1, 2024

Language: Английский

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