Exploiting differences in personal nanoparticle corona profiles for cancer diagnostics DOI Creative Commons
Daniela Pozzi, Giulio Caracciolo

Nanomedicine, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 3

Published: Dec. 9, 2024

Formation Mechanisms of Protein Coronas on Food-Related Nanoparticles: Their Impact on Digestive System and Bioactive Compound Delivery DOI Creative Commons
Xin Rui, Kai Fu, Hao Wang

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(3), P. 512 - 512

Published: Feb. 5, 2025

The rapid development of nanotechnology provides new approaches to manufacturing food-related nanoparticles in various food industries, including formulation, functional foods, packaging, and quality control. Once ingested, will immediately adsorb proteins the biological fluids, forming a corona around them. Protein coronas alter properties nanoparticles, their toxicity, cellular uptake, targeting characteristics, by altering aggregation state. In addition, conformation function enzymes are also influenced formation protein coronas, affecting digestion products. Since inevitable application industries subsequent digestion, comprehensive understanding is essential. This systematic review introduces explains with interactions between nanoparticles. Furthermore, potential origin that migrate from packaging materials fates gastrointestinal tract has been reviewed. Finally, this explores possible effects on bioactive compounds, probiotics prebiotics. Understanding mechanisms crucial, as it enables design tailored delivery systems optimize bioavailability compounds.

Language: Английский

Citations

1

Approaching Two Decades: Biomolecular Coronas and Bio–Nano Interactions DOI
Shiyao Li, Christina Cortez‐Jugo, Yi Ju

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 27, 2024

It has been nearly two decades since the term "protein corona" was coined. This evolved to "biomolecular or "biocorona" capture diverse biomolecules that spontaneously form on surface of nanoparticles upon exposure biological fluids and drive nanoparticle interactions with systems. In this Perspective, we highlight significant progress in field, including studies nonprotein corona components, lipid nanoparticles, role endogenous organ targeting. We also discuss research opportunities particularly need for improved characterization standardization analysis how recent advances artificial intelligence ex vivo models can improve our understanding biomolecular guiding nanomedicine design.

Language: Английский

Citations

4

Magnetic phosphate-based transition Metal-Containing porous Materials: Recent Advances, synthetic Approaches, and applications DOI

Zheng Hongna,

Yue Zhang,

Qin Hai-li

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114496 - 114496

Published: April 1, 2025

Language: Английский

Citations

0

Silver Nanoparticles and Antibiotics: A Promising Synergistic Approach to Multidrug-Resistant Infections DOI Creative Commons
Eudald Casals, Muriel F. Gustà, Neus G. Bastús

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(4), P. 952 - 952

Published: April 21, 2025

The escalating threat of antibiotic resistance demands innovative strategies against multidrug-resistant (MDR) microorganisms, particularly in hospital settings where such infections represent a major global health challenge. Since the rapid growth nanotechnology interdisciplinary research and funding programs 2000s, silver ions have re-emerged as potent antimicrobial agents, offering promising complement to conventional therapies. This therapeutic potential is nowadays explored through use nanoparticles (AgNPs) sources for release. Recent studies shown that controlled ion release enhances efficacy common antibiotics. can be attributed energetically demanding nature bacterial response silver, which weakens metabolism and, turn, overwhelms defenses increases effectiveness. Herein, historical insights into colloidal AgNPs are combined with review recent on exploitation synergistic effect between antibiotics strategy MDR pathogens.

Language: Английский

Citations

0

Molecular insights into the interaction between cytochrome c and carbon nanomaterials. DOI Creative Commons
Ivana Fenoglio,

Shagufta Gul,

Francesco Barbero

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(23), P. e40587 - e40587

Published: Nov. 20, 2024

Carbon nanomaterials (CNMs) are a heterogeneous class of advanced materials. Their widespread use is associated with human safety concerns, which can be addressed by safe-by design strategies. This implies deep knowledge how physico-chemical properties drive biological effects. The ability CNMs to interact cytochrome

Language: Английский

Citations

1

Exploiting differences in personal nanoparticle corona profiles for cancer diagnostics DOI Creative Commons
Daniela Pozzi, Giulio Caracciolo

Nanomedicine, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 3

Published: Dec. 9, 2024

Citations

0