Decoding the regulatory roles of circular RNAs in cardiac fibrosis DOI Creative Commons

Qianhui You,

Jiajing Yu,

Rongfang Pan

et al.

Non-coding RNA Research, Journal Year: 2024, Volume and Issue: 11, P. 115 - 130

Published: Dec. 9, 2024

Cardiovascular diseases (CVDs) are the primary cause of death globally. The evolution nearly all types CVDs is characterized by a common theme: emergence cardiac fibrosis. precise mechanisms that trigger fibrosis still not completely understood. In recent years, type non-coding regulatory RNA molecule known as circular RNAs (circRNAs) has been reported. These molecules produced during back splicing and possess significant biological capabilities, such regulating microRNA activity, serving protein scaffolds recruiters, competing with mRNA, forming circR-loop structures to modulate transcription, translating polypeptides. Furthermore, circRNAs exhibit substantial abundance, notable stability, specificity tissues, cells, time, endowing them potential biomarkers, therapeutic targets, agents. CircRNAs have garnered growing interest in field CVDs. Recent investigations into involvement yielded encouraging findings. This study aims provide concise overview existing knowledge about roles

Language: Английский

EXPLORING THE ROLE OF LONG NON-CODING RNAs AS BIOMARKERS IN CARDIOVASCULAR DISEASE: A BIBLIOMETRIC ANALYSIS DOI
Arthisri Anandhi Sekar, Vishnu Priya Veeraraghavan,

T A

et al.

BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY, Journal Year: 2025, Volume and Issue: unknown, P. 123 - 140

Published: March 20, 2025

Background: Cardiovascular diseases (CVDs) are a leading cause of mortality globally, necessitating novel biomarkers for diagnosis and treatment. Long non-coding RNAs (lncRNAs) have emerged as significant regulatory molecules in cardiovascular biology, yet comprehensive bibliometric analyses this area lacking. Objective: This study aims to conduct analysis lncRNAs CVD identify publication trends, key contributors, thematic developments from 2008 2023. Methods: A systematic search was performed across PubMed, Scopus, Web Science using the keywords "((Long RNA) OR (lncRNA)) AND (Cardiovascular disease) disorders) (Biomarkers)." total 33,805 records were retrieved, with duplicates removed, resulting 29,545 unique records. After screening, 341 relevant articles selected VOSviewer. Results: publications analyzed, involving 54 countries/regions, 548 institutions, 1744 authors 177 journals. The United States (84 publications) China (61 contributors. Zhengzhou University had highest output, while Guo Wei most prolific author. Keyword revealed focus on lncRNAs' roles occurrence, development, diagnosis, treatment, prognosis CVD. Conclusion: provides insights into research landscape CVD, highlighting influential authors, collaborative networks. findings underscore importance suggest potential areas future investigation

Language: Английский

Citations

0
Knowledge mapping and research trends of accidental falls in patients with Parkinson’s disease from 2003 to 2023: a bibliometric analysis DOI Creative Commons

Luya Shi,

Bongsook Yih

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 22, 2024

Background Recent years have witnessed a rapid growth in research on accidental falls patients with Parkinson’s Disease (PD). However, comprehensive and systematic bibliometric analysis is still lacking. This study aims to systematically analyze the current status development trends of related PD using methods. Methods We retrieved literature published between January 1, 2003, December 31, 2023, from Web Science Core Collection (WoSCC) database. Statistical knowledge mapping were conducted VOSviewer, CiteSpace, Microsoft Excel software. Results A total 3,195 publications retrieved. These articles authored by 13,202 researchers 3,834 institutions across 87 countries 200 academic journals. Over past 20 years, number citations has increased annually. The United States Kingdom highest this field, while Harvard University Tel Aviv are most influential institutions. Parkinsonism & Related Disorders journal articles, Movement had citations. prolific author Bloem, Bastiaan R, cited Hausdorff, Jeffrey. main areas these Neurosciences, Biomedical, Electrical Electronic, Biochemistry Molecular Biology. Currently, high-frequency keywords include risk factors, clinical manifestations, interventions. Prediction prevention such topic significant potential currently major focus research. Conclusion used reveal hotspots field PD. It also points out directions for future can provide theoretical support practical guidance scholars further conduct

Language: Английский

Citations

1
Circular RNAs interplay with Coronary Microvascular Dysfunction: A prognostic key for patients with coronary artery disease? DOI
Chiara Foglieni

International Journal of Cardiology, Journal Year: 2024, Volume and Issue: 418, P. 132600 - 132600

Published: Sept. 25, 2024

Language: Английский

Citations

0
Decoding the regulatory roles of circular RNAs in cardiac fibrosis DOI Creative Commons

Qianhui You,

Jiajing Yu,

Rongfang Pan

et al.

Non-coding RNA Research, Journal Year: 2024, Volume and Issue: 11, P. 115 - 130

Published: Dec. 9, 2024

Cardiovascular diseases (CVDs) are the primary cause of death globally. The evolution nearly all types CVDs is characterized by a common theme: emergence cardiac fibrosis. precise mechanisms that trigger fibrosis still not completely understood. In recent years, type non-coding regulatory RNA molecule known as circular RNAs (circRNAs) has been reported. These molecules produced during back splicing and possess significant biological capabilities, such regulating microRNA activity, serving protein scaffolds recruiters, competing with mRNA, forming circR-loop structures to modulate transcription, translating polypeptides. Furthermore, circRNAs exhibit substantial abundance, notable stability, specificity tissues, cells, time, endowing them potential biomarkers, therapeutic targets, agents. CircRNAs have garnered growing interest in field CVDs. Recent investigations into involvement yielded encouraging findings. This study aims provide concise overview existing knowledge about roles

Language: Английский

Citations

0