Serum lncRNA ITGB2-AS1 and ICAM-1 as novel biomarkers for rheumatoid arthritis and osteoarthritis diagnosis DOI Creative Commons

Aliaa M. Selim,

Yumn A. Elsabagh,

Maha M. El‐Sawalhi

et al.

BMC Medical Genomics, Journal Year: 2024, Volume and Issue: 17(1)

Published: Oct. 8, 2024

The complete circulating long non-coding RNAs (lncRNAs) signature of rheumatoid arthritis (RA) and osteoarthritis (OA) is still uncovered. lncRNA integrin subunit beta 2 (ITGB2)-anti-sense RNA 1 (ITGB2-AS1) affects ITGB2 expression; however, there a gap in knowledge regarding its expression clinical usefulness RA OA. This study investigated the potential serum ITGB2-AS1 as novel diagnostic biomarker correlation with ligand intercellular adhesion molecule-1 (ICAM-1), disease activity, severity primary knee OA patients.

Language: Английский

Serum lncRNA ITGB2-AS1 and ICAM-1 as novel biomarkers for rheumatoid arthritis and osteoarthritis diagnosis DOI Creative Commons

Aliaa M. Selim,

Yumn A. Elsabagh,

Maha M. El‐Sawalhi

et al.

BMC Medical Genomics, Journal Year: 2024, Volume and Issue: 17(1)

Published: Oct. 8, 2024

The complete circulating long non-coding RNAs (lncRNAs) signature of rheumatoid arthritis (RA) and osteoarthritis (OA) is still uncovered. lncRNA integrin subunit beta 2 (ITGB2)-anti-sense RNA 1 (ITGB2-AS1) affects ITGB2 expression; however, there a gap in knowledge regarding its expression clinical usefulness RA OA. This study investigated the potential serum ITGB2-AS1 as novel diagnostic biomarker correlation with ligand intercellular adhesion molecule-1 (ICAM-1), disease activity, severity primary knee OA patients.

Language: Английский

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