Effect of baseline cannabis use and working‐memory network function on changes in cannabis use in heavy cannabis users: A prospective fMRI study DOI
Janna Cousijn, Reínout W. Wiers,

K. Richard Ridderinkhof

et al.

Human Brain Mapping, Journal Year: 2013, Volume and Issue: 35(5), P. 2470 - 2482

Published: Sept. 3, 2013

Abstract Theoretical models of addiction suggest that a substance use disorder represents an imbalance between hypersensitive motivational processes and deficient regulatory executive functions. Working‐memory (a central function) may be powerful predictor the course drug drug‐related problems. Goal current functional magnetic resonance imaging study was to assess predictive power working‐memory network function for future cannabis cannabis‐related problem severity in heavy users. Tensor independent component analysis used investigate differences 32 users 41 nonusing controls during N ‐back task. In addition, associations were examined at baseline 6‐month follow‐up. Behavioral performance did not significantly differ controls. However, among users, individual response had effect on change weekly 6 months later (Δ R 2 = 0.11, P 0.006, f 0.37) beyond 0.41) behavioral measure approach bias 0.18): stronger task related increase use. These findings imply requiring greater effort accurately complete have higher probability escalating biomarker prediction treatment outcome Hum Brain Mapp 35:2470–2482, 2014 . © 2013 Wiley Periodicals, Inc

Language: Английский

The Endocannabinoid System and the Brain DOI
Raphael Mechoulam, Linda A. Parker

Annual Review of Psychology, Journal Year: 2012, Volume and Issue: 64(1), P. 21 - 47

Published: July 19, 2012

The psychoactive constituent in cannabis, Δ(9)-tetrahydrocannabinol (THC), was isolated the mid-1960s, but cannabinoid receptors, CB1 and CB2, major endogenous cannabinoids (anandamide 2-arachidonoyl glycerol) were identified only 20 to 25 years later. system affects both central nervous (CNS) peripheral processes. In this review, we have tried summarize research--with an emphasis on recent publications--on actions of endocannabinoid anxiety, depression, neurogenesis, reward, cognition, learning, memory. effects are at times biphasic--lower doses causing opposite those seen high doses. Recently, numerous endocannabinoid-like compounds been brain. Only a few investigated for their CNS activity, future investigations action may throw light wide spectrum brain functions.

Language: Английский

Citations

995

Advancing understanding of executive function impairments and psychopathology: bridging the gap between clinical and cognitive approaches DOI Creative Commons
Hannah R. Snyder, Akira Miyake, Benjamin L. Hankin

et al.

Frontiers in Psychology, Journal Year: 2015, Volume and Issue: 6

Published: March 26, 2015

Executive function (EF) is essential for successfully navigating nearly all of our daily activities. Of critical importance clinical psychological science, EF impairments are associated with most forms psychopathology. However, despite the proliferation research on in populations, notable exceptions and cognitive approaches to have remained largely independent, leading failures apply theoretical methodological advances one field other hindering progress. First, we review current state knowledge psychopathology limitations previous light recent understanding measuring EF. Next, offer concrete suggestions improving assessment. Last, suggest future directions, including integrating modern models art, hierarchical dimensional as well translational implications EF-informed science.

Language: Английский

Citations

828

Cognitive Bias Modification and Cognitive Control Training in Addiction and Related Psychopathology DOI
Reínout W. Wiers, Thomas E. Gladwin, Wilhelm Hofmann

et al.

Clinical Psychological Science, Journal Year: 2013, Volume and Issue: 1(2), P. 192 - 212

Published: Jan. 9, 2013

The past decade has witnessed a surge in research on training paradigms aimed at directly influencing cognitive processes addiction and other psychopathology. Broadly, two avenues have been explored: In the first, aim was to change maladaptive motivational biases (cognitive bias modification); second, increase general control (e.g., working memory capacity). These approaches are consistent with dual-process perspective which psychopathology is related combination of disorder-specific impulsive weak abilities these impulses view reflective longer-term considerations. After reviewing evidence for models addiction, we discuss number critical issues, along suggestions further research. We argue that theoretical advancement, better understanding underlying neurocognitive processes, crucial adequately responding recent criticisms optimizing use clinical practice.

Language: Английский

Citations

463

Adolescent neurocognitive development and impacts of substance use: Overview of the adolescent brain cognitive development (ABCD) baseline neurocognition battery DOI Creative Commons
Mónica Luciana, James M. Bjork, Bonnie J. Nagel

et al.

Developmental Cognitive Neuroscience, Journal Year: 2018, Volume and Issue: 32, P. 67 - 79

Published: Feb. 21, 2018

Adolescence is characterized by numerous social, hormonal and physical changes, as well a marked increase in risk-taking behaviors. Dual systems models attribute adolescent to tensions between developing capacities for cognitive control motivational strivings, which may peak at this time. A comprehensive understanding of neurocognitive development during the period necessary permit distinction premorbid vulnerabilities consequences behaviors such substance use. Thus, prospective assessment fundamental aims newly launched Adolescent Brain Cognitive Development (ABCD) Consortium. This paper details rationale ABC'lected measures neurocognition, presents preliminary descriptive data on an initial sample 2299 participants, provides context how large-scale project can inform our neurodevelopment.

Language: Английский

Citations

462

Neuroimaging Impaired Response Inhibition and Salience Attribution in Human Drug Addiction: A Systematic Review DOI Creative Commons
Anna Zilverstand, Anna Huang, Nelly Alia‐Klein

et al.

Neuron, Journal Year: 2018, Volume and Issue: 98(5), P. 886 - 903

Published: June 1, 2018

Language: Английский

Citations

440

Approach bias modification in alcohol dependence: Do clinical effects replicate and for whom does it work best? DOI Creative Commons

Carolin Eberl,

Reínout W. Wiers,

Steffen Pawelczack

et al.

Developmental Cognitive Neuroscience, Journal Year: 2012, Volume and Issue: 4, P. 38 - 51

Published: Nov. 14, 2012

Language: Английский

Citations

407

Why young people's substance use matters for global health DOI
Wayne Hall, George Patton, Emily Stockings

et al.

The Lancet Psychiatry, Journal Year: 2016, Volume and Issue: 3(3), P. 265 - 279

Published: Feb. 20, 2016

Language: Английский

Citations

298

Effects of Cannabis on Neurocognitive Functioning: Recent Advances, Neurodevelopmental Influences, and Sex Differences DOI
Natania A. Crane, Randi M. Schuster, Paolo Fusar‐Poli

et al.

Neuropsychology Review, Journal Year: 2012, Volume and Issue: 23(2), P. 117 - 137

Published: Nov. 5, 2012

Language: Английский

Citations

286

Characterizing the cognitive effects of cocaine: A comprehensive review DOI
Desirée Spronk,

Janelle H. P. van Wel,

Johannes G. Ramaekers

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2013, Volume and Issue: 37(8), P. 1838 - 1859

Published: July 20, 2013

Language: Английский

Citations

235

Neuropsychological consequences of chronic opioid use: A quantitative review and meta-analysis DOI
Alex Baldacchino, David J.K. Balfour,

Filippo Passetti

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2012, Volume and Issue: 36(9), P. 2056 - 2068

Published: July 6, 2012

Language: Английский

Citations

235